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Highly accurate biomolecular structure prediction is a key component of developing biomolecular foundation models, and one of the most critical aspects of building foundation models is identifying the recipes for scaling the model. In this…

Biomolecules · Quantitative Biology 2026-01-02 Yi Zhou , Chan Lu , Yiming Ma , Wei Qu , Fei Ye , Kexin Zhang , Lan Wang , Minrui Gui , Quanquan Gu

Fine-tuning pre-trained foundation models has gained significant popularity in various research fields. Existing methods for fine-tuning can be roughly divided into two categories, namely Parameter-Efficient Fine-Tuning and High-Performance…

Computer Vision and Pattern Recognition · Computer Science 2023-12-27 Peng Ye , Yongqi Huang , Chongjun Tu , Minglei Li , Tao Chen , Tong He , Wanli Ouyang

3D field-programmable gate arrays (FPGAs) promise higher performance through vertical integration. However, existing placement tools, largely inherited from 2D frameworks, fail to capture the unique delay characteristics and optimization…

Hardware Architecture · Computer Science 2026-04-02 Cong Hao , Andrew B. Kahng , Bodhisatta Pramanik , Ismael Youssef

In recent years, the multiple-stage strategy has become a popular trend for visual tracking. This strategy first utilizes a base tracker to coarsely locate the target and then exploits a refinement module to obtain more accurate results.…

Computer Vision and Pattern Recognition · Computer Science 2021-04-06 Bin Yan , Dong Wang , Huchuan Lu , Xiaoyun Yang

As the large language models (LLMs) grow in size each day, efficient training and fine-tuning has never been as important as nowadays. This resulted in the great interest in parameter efficient fine-tuning (PEFT), and effective methods…

Machine Learning · Computer Science 2025-11-04 Dhananjaya Gowda , Seoha Song , Junhyun Lee , Harshith Goka

Modern field programmable gate array(FPGA) can be partially dynamically reconfigurable with heterogeneous resources distributed on the chip. And FPGA-based partially dynamically reconfigurable system(FPGA-PDRS) can be used to accelerate…

Systems and Control · Electrical Eng. & Systems 2022-12-13 Bo Ding , Jinglei Huang , Junpeng Wang , Qi Xu , Song Chen , Yi Kang

Low-Rank Adaptation (LoRA) is a widely used finetuning method for large models. Its small memory footprint allows practitioners to adapt large models to specific tasks at a fraction of the cost of full finetuning. Different modifications…

Machine Learning · Computer Science 2025-06-26 Soufiane Hayou , Nikhil Ghosh , Bin Yu

Building design directly affects human well-being and carbon emissions, yet generating spatial-functional and energy-compliant floorplans remains manual, costly, and non-scalable. Existing methods produce visually plausible layouts but…

Artificial Intelligence · Computer Science 2025-12-02 Pengyu Zeng , Yuqin Dai , Jun Yin , Jing Zhong , Ziyang Han , Chaoyang Shi , ZhanXiang Jin , Maowei Jiang , Yuxing Han , Shuai Lu

Advanced feedforward control methods enable mechatronic systems to perform varying motion tasks with extreme accuracy and throughput. The aim of this paper is to develop a data-driven feedforward controller that addresses input…

Systems and Control · Electrical Eng. & Systems 2023-11-30 Jilles van Hulst , Maurice Poot , Dragan Kostić , Kai Wa Yan , Jim Portegies , Tom Oomen

The increasing transistor scale integration poses, among others, the thermal-aware floorplanning problem; consisting of how to place the hardware components in order to reduce overheating by dissipation. Due to the huge amount of feasible…

Hardware Architecture · Computer Science 2023-03-08 Ignacio Arnaldo , Alfredo Cuesta-Infante , J. Manuel Colmenar , José L. Risco-Martín , José L. Ayala

Large pre-trained models achieve remarkable success across diverse domains, yet fully fine-tuning incurs prohibitive computational and memory costs. Parameter-efficient fine-tuning (PEFT) has thus become a mainstream paradigm. Among them,…

Machine Learning · Computer Science 2026-02-02 Muqing Liu , Chongjie Si , Yuheng Jia

Growing demands in the semiconductor industry result in the need for enhanced performance of lithographic equipment. However, position tracking accuracy of high precision mechatronics is often limited by the presence of disturbance sources,…

Systems and Control · Electrical Eng. & Systems 2021-05-05 Ioannis Proimadis , Yorick Broens , Roland Tóth , Hans Butler

Parameter-efficient fine-tuning aims to achieve performance comparable to fine-tuning, using fewer trainable parameters. Several strategies (e.g., Adapters, prefix tuning, BitFit, and LoRA) have been proposed. However, their designs are…

Computation and Language · Computer Science 2023-01-06 Jiaao Chen , Aston Zhang , Xingjian Shi , Mu Li , Alex Smola , Diyi Yang

Evolutionary algorithms can outperform conventional placement algorithms such as simulated annealing, analytical placement as well as manual placement on metrics such as runtime, wirelength, pipelining cost, and clock frequency when mapping…

Hardware Architecture · Computer Science 2020-07-21 Niansong Zhang , Xiang Chen , Nachiket Kapre

There is a set of rectangular macros with given dimensions, and there are wires connecting some pairs (or sets) of them. We have a placement area where these macros should be placed without overlaps in order to minimize the total length of…

Data Structures and Algorithms · Computer Science 2015-09-08 Endre Csóka , Attila Deák

3D stacked technology has emerged as an effective mechanism to overcome physical limits and communication delays found in 2D integration. However, 3D technology also presents several drawbacks that prevent its smooth application. Two of the…

Hardware Architecture · Computer Science 2024-02-23 David Cuesta , José L. Risco-Martín , José L. Ayala , J. Ignacio Hidalgo

As technology advances, photonic integrated circuits (PICs) are rapidly scaling in size and complexity, with modern designs integrating thousands of components. However, the analog custom layout nature of photonics, the curvy waveguide…

Emerging Technologies · Computer Science 2025-10-27 Hongjian Zhou , Haoyu Yang , Nicholas Gangi , Haoxing Ren , Rena Huang , Jiaqi Gu

Despite recent advancements in the field of medical image analysis with the use of pretrained foundation models, the issue of distribution shifts between cross-source images largely remains adamant. To circumvent that issue, investigators…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Sanjaya Poudel , Nikita Kunwor , Raj Simkhada , Mustafa Munir , Manish Dhakal , Khem Poudel

Providing robots with large-scale robot skin is a challenging goal, especially when considering surfaces characterized by different shapes and curvatures. The problem originates from technological advances in tactile sensing, and in…

Robotics · Computer Science 2017-11-29 Xuenan Guo , Fulvio Mastrogiovanni

A chiplet is an integrated circuit that encompasses a well-defined subset of an overall system's functionality. In contrast to traditional monolithic system-on-chips (SoCs), chiplet-based architecture can reduce costs and increase…

Hardware Architecture · Computer Science 2023-12-12 Shixin Chen , Shanyi Li , Zhen Zhuang , Su Zheng , Zheng Liang , Tsung-Yi Ho , Bei Yu , Alberto L. Sangiovanni-Vincentelli