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Depression is a widespread mental health issue affecting diverse age groups, with notable prevalence among college students and the elderly. However, existing datasets and detection methods primarily focus on young adults, neglecting the…

Clinical practice in psychiatry is burdened with the increased demand for healthcare services and the scarce resources available. New paradigms of health data powered with machine learning techniques could open the possibility to improve…

Artificial Intelligence · Computer Science 2023-06-08 Juan Sebastian Canas , Francisco Gomez , Omar Costilla-Reyes

The widespread availability of complex time series data in various domains such as environmental science, epidemiology, and economics demands robust causal discovery methods that can identify intricate contemporaneous and lagged…

Machine Learning · Computer Science 2026-05-12 Omar Faruque , Sahara Ali , Xue Zheng , Jianwu Wang

Most approaches for assessing causality in complex dynamical systems fail when the interactions between variables are inherently non-linear and non-stationary. Here we introduce Temporal Autoencoders for Causal Inference (TACI), a…

Machine Learning · Computer Science 2024-06-06 Josuan Calderon , Gordon J. Berman

Recently, the potential of dynamic brain networks as a neuroimaging biomarkers for mental illnesses is being increasingly recognized. However, there are several unmet challenges in developing such biomarkers, including the need for methods…

Neurons and Cognition · Quantitative Biology 2019-10-10 Suprateek Kundu , Jin Ming , Jennifer Stevens

Complexity measures in the context of the Integrated Information Theory of consciousness try to quantify the strength of the causal connections between different neurons. This is done by minimizing the KL-divergence between a full system…

Methodology · Statistics 2021-02-09 Carlotta Langer , Nihat Ay

Parkinson's disease (PD) belongs to the class of neurodegenerative disorders that affect the central nervous system. It is usually defined as the gradual loss of dopaminergic neurons in the substantia nigra pars compacta, which causes both…

Neurons and Cognition · Quantitative Biology 2024-11-01 Hina Shaheen , Roderick Melnik

Repetitive Transcranial Magnetic Stimulation (rTMS) is a well-supported, evidence-based treatment for depression. However, patterns of response to this treatment are inconsistent. Emerging evidence suggests that artificial intelligence can…

Machine Learning · Computer Science 2024-04-29 Matthew Squires , Xiaohui Tao , Soman Elangovan , Raj Gururajan , Haoran Xie , Xujuan Zhou , Yuefeng Li , U Rajendra Acharya

Recent years have seen an increased focus into the tasks of predicting hospital inpatient risk of deterioration and trajectory evolution due to the availability of electronic patient data. A common approach to these problems involves…

Machine Learning · Computer Science 2020-11-18 Henrique Aguiar , Mauro Santos , Peter Watkinson , Tingting Zhu

Single subject prediction of brain disorders from neuroimaging data has gained increasing attention in recent years. Yet, for some heterogeneous disorders such as major depression disorder (MDD) and autism spectrum disorder (ASD), the…

Machine Learning · Computer Science 2022-06-08 Ahmed El Gazzar , Rajat Mani Thomas , Guido Van Wingen

Parkinson's disease (PD) is a common neurodegenerative disease with a high degree of heterogeneity in its clinical features, rate of progression, and change of variables over time. In this work, we present a novel data-driven, network-based…

Applications · Statistics 2020-07-01 Sanjukta Krishnagopal , Rainer Von Coelln , Lisa M. Shulman , Michelle Girvan

Diagnosis of Parkinson's disease (PD) is commonly based on medical observations and assessment of clinical signs, including the characterization of a variety of motor symptoms. However, traditional diagnostic approaches may suffer from…

Machine Learning · Computer Science 2020-10-14 Jie Mei , Christian Desrosiers , Johannes Frasnelli

Concepts of Granger causality (GC) and Granger autonomy (GA) are central to assess the dynamics of coupled physiologic processes. While causality measures have been already proposed and applied in time and frequency domains, measures…

Signal Processing · Electrical Eng. & Systems 2023-07-20 Laura Sparacino , Yuri Antonacci , Chiara Barà , Angela Valenti , Alberto Porta , Luca Faes

Understanding the temporal properties of longitudinal data is critical for identifying trends, predicting future events, and making informed decisions in any field where temporal data is analysed, including health and epidemiology, finance,…

Digital phenotyping offers a novel and cost-efficient approach for managing depression and anxiety. Previous studies, often limited to small-to-medium or specific populations, may lack generalizability. We conducted a cross-sectional…

Causal discovery from observational data is fundamental to scientific fields like biology, where controlled experiments are often impractical. However, existing methods, including constraint-based (e.g., PC, causalMGM) and score-based…

Machine Learning · Computer Science 2025-10-14 Zhenjiang Fan , Zengyi Qin , Yuanning Zheng , Bo Xiong , Summer Han

In this paper we present the concept of description of random processes in complex systems with the discrete time. It involves the description of kinetics of discrete processes by means of the chain of finite-difference non-Markov equations…

Statistical Mechanics · Physics 2009-10-31 Renat Yulmetyev , Reter Hanggi , Fail Gafarov

The dynamic characteristics of multiphase industrial processes present significant challenges in the field of industrial big data modeling. Traditional soft sensing models frequently neglect the process dynamics and have difficulty in…

Machine Learning · Computer Science 2024-07-09 Yimeng He , Le Yao , Xinmin Zhang , Xiangyin Kong , Zhihuan Song

Recurrent major mood episodes and subsyndromal mood instability cause substantial disability in patients with bipolar disorder. Early identification of mood episodes enabling timely mood stabilisation is an important clinical goal. Recent…

Machine Learning · Statistics 2017-08-04 Andrey Kormilitzin , Kate E. A. Saunders , Paul J. Harrison , John R. Geddes , Terry Lyons

Diagnostic processes for complex cyber-physical systems often require extensive prior knowledge in the form of detailed system models or comprehensive training data. However, obtaining such information poses a significant challenge. To…

Artificial Intelligence · Computer Science 2025-06-13 Henrik Sebastian Steude , Alexander Diedrich , Ingo Pill , Lukas Moddemann , Daniel Vranješ , Oliver Niggemann