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Understanding the evolution of brain functional networks over time is of great significance for the analysis of cognitive mechanisms and the diagnosis of neurological diseases. Existing methods often have difficulty in capturing the…

Machine Learning · Computer Science 2025-10-30 Tianqi Guo , Liping Chen , Ciyuan Peng , Jingjing Zhou , Jing Ren

At present, the vast majority of human subjects with neurological disease are still diagnosed through in-person assessments and qualitative analysis of patient data. In this paper, we propose to use Topological Data Analysis (TDA) together…

Machine Learning · Computer Science 2020-05-07 Afra Nawar , Farhan Rahman , Narayanan Krishnamurthi , Anirudh Som , Pavan Turaga

Identifying the onset of emotional stress in older patients with mood disorders and chronic pain is crucial in mental health studies. To this end, studying the associations between passively sensed variables that measure human behaviors and…

Methodology · Statistics 2025-11-11 Younghoon Kim , Sumanta Basu , Samprit Banerjee

Major Depressive Disorder is one of the leading causes of disability worldwide, yet its diagnosis still depends largely on subjective clinical assessments. Integrating Artificial Intelligence (AI) holds promise for developing objective,…

Artificial Intelligence · Computer Science 2026-05-01 Dorsa Macky Aleagha , Payam Zohari , Mostafa Haghir Chehreghani

Multivariate dynamical processes can often be intuitively described by a weighted connectivity graph between components representing each individual time-series. Even a simple representation of this graph as a Pearson correlation matrix may…

Machine Learning · Computer Science 2022-02-15 Usman Mahmood , Zening Fu , Vince Calhoun , Sergey Plis

Depression manifests through a diverse set of symptoms such as sleep disturbance, loss of interest, and concentration difficulties. However, most existing works treat depression prediction either as a binary label or an overall severity…

Computation and Language · Computer Science 2026-02-18 Chaithra Nerella , Chiranjeevi Yarra

Traditionally, the regime of mental healthcare has followed an episodic psychotherapy model wherein patients seek care from a provider through a prescribed treatment plan developed over multiple provider visits. Recent advances in wearable…

Major depressive disorder (MDD) is a heterogeneous condition; multiple underlying neurobiological substrates could be associated with treatment response variability. Understanding the sources of this variability and predicting outcomes has…

Activity and motion analysis has the potential to be used as a diagnostic tool for mental disorders. However, to-date, little work has been performed in turning stratification measures of activity into useful symptom markers. The research…

Medical Physics · Physics 2019-08-19 Maxim Osipov

A number of challenges exist for the analysis of mHealth data: maintaining participant engagement over extended time periods and therefore understanding what constitutes an acceptable threshold of missing data; distinguishing between the…

Objective: This work introduces a framework for multivariate time series analysis aimed at detecting and quantifying collective emerging behaviors in the dynamics of physiological networks. Methods: Given a network system mapped by a vector…

Applications · Statistics 2025-02-04 Luca Faes , Gorana Mijatovic , Laura Sparacino , Alberto Porta

Identifying the main features and learning the causal relationships of a dynamic system from time-series of sensor data are key problems in many real-world robot applications. In this paper, we propose an extension of a state-of-the-art…

Robotics · Computer Science 2023-02-21 Luca Castri , Sariah Mghames , Marc Hanheide , Nicola Bellotto

We frequently encounter multiple series that are temporally correlated in our surroundings, such as EEG data to examine alterations in brain activity or sensors to monitor body movements. Segmentation of multivariate time series data is a…

Machine Learning · Computer Science 2024-10-23 Shima Imani , Harsh Shrivastava

Mental health disorders remain a significant challenge in modern healthcare, with diagnosis and treatment often relying on subjective patient descriptions and past medical history. To address this issue, we propose a personalized mental…

Machine Learning · Computer Science 2023-07-12 Manan Shukla , Oshani Seneviratne

Parkinson's disease (PD) presents a growing global challenge, affecting over 10 million individuals, with prevalence expected to double by 2040. Early diagnosis remains difficult due to the late emergence of motor symptoms and limitations…

Machine Learning · Computer Science 2025-10-21 Arianna Francesconi , Donato Cappetta , Fabio Rebecchi , Paolo Soda , Valerio Guarrasi , Rosa Sicilia

Automatic depression detection from conversational interactions holds significant promise for scalable screening but remains hindered by severe data scarcity and a lack of clinical interpretability. Existing approaches typically rely on…

Computation and Language · Computer Science 2026-04-28 Rishitej Reddy Vyalla , Kritarth Prasad , Avinash Anand , Erik Cambria , Shaoxiong Ji , Faten S. Alamri , Zhengkui Wang

We describe the development of a model to detect user-level clinical depression based on a user's temporal social media posts. Our model uses a Depression Symptoms Detection (DSD) classifier, which is trained on the largest existing samples…

Computation and Language · Computer Science 2023-03-31 Nawshad Farruque , Randy Goebel , Sudhakar Sivapalan , Osmar R. Zaïane

Healthcare decision-making requires not only accurate predictions but also insights into how factors influence patient outcomes. While traditional Machine Learning (ML) models excel at predicting outcomes, such as identifying high risk…

Machine Learning · Computer Science 2025-01-28 Sheresh Zahoor , Pietro Liò , Gaël Dias , Mohammed Hasanuzzaman

Understanding the biological and behavioral heterogeneity underlying psychiatric disorders is critical for advancing precision diagnosis, treatment, and prevention. This paper addresses the scientific question of how multimodal data,…

Methodology · Statistics 2025-11-10 Yinjun Zhao , Yuanjia Wang , Ying LIu

Mood disorders are common and associated with significant morbidity and mortality. Early diagnosis has the potential to greatly alleviate the burden of mental illness and the ever increasing costs to families and society. Mobile devices…

Human-Computer Interaction · Computer Science 2018-08-30 He Huang , Bokai Cao , Philip S. Yu , Chang-Dong Wang , Alex D. Leow