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Featurizing microscopy images for use in biological research remains a significant challenge, especially for large-scale experiments spanning millions of images. This work explores the scaling properties of weakly supervised classifiers and…

Determining company similarity is a vital task in finance, underpinning risk management, hedging, and portfolio diversification. Practitioners often rely on sector and industry classifications such as SIC and GICS codes to gauge similarity,…

Sparse autoencoders (SAEs) provide a powerful mechanism for decomposing the dense representations produced by Large Language Models (LLMs) into interpretable latent features. We posit that SAEs constitute a natural foundation for Learned…

Machine Learning · Computer Science 2026-03-17 Thibault Formal , Maxime Louis , Hervé Dejean , Stéphane Clinchant

Learning-based surrogate models have become a practical alternative to high-fidelity CFD solvers, but their latent representations remain opaque and hinder adoption in safety-critical or regulation-bound settings. This work introduces a…

Computational Engineering, Finance, and Science · Computer Science 2025-07-23 Yeping Hu , Shusen Liu

Recently, sparse autoencoders (SAEs) have emerged as a promising technique for interpreting activations in foundation models by disentangling features into a sparse set of concepts. However, identifying the optimal level of sparsity for…

Machine Learning · Computer Science 2026-04-17 Dongsheng Wang , Jinsen Zhang , Dawei Su , Hui Huang

Sparse Autoencoders (SAEs) have emerged as a powerful tool for interpreting the internal representations of CLIP vision encoders, yet existing analyses largely focus on the semantic meaning of individual features. We introduce information…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Yusung Ro , Jaehyun Choi , Junmo Kim

Sparse auto-encoders (SAEs) have re-emerged as a prominent method for mechanistic interpretability, yet they face two significant challenges: the non-smoothness of the $L_1$ penalty, which hinders reconstruction and scalability, and a lack…

Artificial Intelligence · Computer Science 2026-05-19 Ouns El Harzli , Hugo Wallner , Yoonsoo Nam , Haixuan Xavier Tao

Cancer is a complex disease with significant social and economic impact. Advancements in high-throughput molecular assays and the reduced cost for performing high-quality multi-omics measurements have fuelled insights through machine…

Machine Learning · Computer Science 2022-06-28 Pedro Henrique da Costa Avelar , Roman Laddach , Sophia Karagiannis , Min Wu , Sophia Tsoka

Sparse Autoencoder (SAE) features have become essential tools for mechanistic interpretability research. SAE features are typically characterized by examining their activating examples, which are often "monosemantic" and align with human…

Artificial Intelligence · Computer Science 2025-09-30 Claire Tian , Katherine Tian , Nathan Hu

Motivation: Despite advances in the computational analysis of high-throughput molecular profiling assays (e.g. transcriptomics), a dichotomy exists between methods that are simple and interpretable, and ones that are complex but with lower…

Machine Learning · Computer Science 2023-06-12 Pedro Henrique da Costa Avelar , Min Wu , Sophia Tsoka

Analysis of somatic mutation profiles from cancer patients is essential in the development of cancer research. However, the low frequency of most mutations and the varying rates of mutations across patients makes the data extremely…

Identifying the features learned by neural networks is a core challenge in mechanistic interpretability. Sparse autoencoders (SAEs), which learn a sparse, overcomplete dictionary that reconstructs a network's internal activations, have been…

Machine Learning · Computer Science 2024-05-27 Dan Braun , Jordan Taylor , Nicholas Goldowsky-Dill , Lee Sharkey

Accurate classification of pediatric central nervous system tumors remains challenging due to histological complexity and limited training data. While pathology foundation models have advanced whole-slide image (WSI) analysis, they often…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Jian Yu , Joakim Nguyen , Jinrui Fang , Awais Naeem , Zeyuan Cao , Sanjay Krishnan , Nicholas Konz , Tianlong Chen , Chandra Krishnan , Hairong Wang , Edward Castillo , Ying Ding , Ankita Shukla

Motivated by the hypothesis that neural network representations encode abstract, interpretable features as linearly accessible, approximately orthogonal directions, sparse autoencoders (SAEs) have become a popular tool in interpretability.…

Machine Learning · Computer Science 2025-11-05 Valérie Costa , Thomas Fel , Ekdeep Singh Lubana , Bahareh Tolooshams , Demba Ba

Recommendation model interpretation aims to reveal the relationships between inputs, model internal representations and outputs to enhance the transparency, interpretability, and trustworthiness of recommendation systems. However, the…

Information Retrieval · Computer Science 2026-01-27 Jiayin Wang , Xiaoyu Zhang , Weizhi Ma , Zhiqiang Guo , Min Zhang

Sparse autoencoders (SAEs) enable feature-level mechanistic interpretability and activation steering in large language models (LLMs), but SAE-based language control remains unreliable in multilingual settings: most SAEs are trained on…

Computation and Language · Computer Science 2026-05-25 Yusser Al Ghussin , Daniil Gurgurov , Tanja Baeumel , Josef van Genabith , Patrick Schramowski , Simon Ostermann

Sparse Autoencoders (SAEs) have shown to find interpretable features in neural networks from polysemantic neurons caused by superposition. Previous work has shown SAEs are an effective tool to extract interpretable features from the early…

Computer Vision and Pattern Recognition · Computer Science 2025-04-17 Matthew Bozoukov

Sparse autoencoders (SAEs) have been widely used for interpretability of neural networks, but their learned features often vary across seeds and hyperparameter settings. We introduce Ordered Sparse Autoencoders (OSAE), which extend…

Machine Learning · Computer Science 2025-12-03 Sophie L. Wang , Alex Quach , Nithin Parsan , John J. Yang

Understanding the multilingual mechanisms of large language models (LLMs) provides insight into how they process different languages, yet this remains challenging. Existing studies often focus on individual neurons, but their polysemantic…

Reliable control of myoelectric prostheses is often hindered by high inter-subject variability and the clinical impracticality of high-density sensor arrays. This study proposes a deep learning framework for accurate gesture recognition…