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Protein structure prediction often hinges on multiple sequence alignments (MSAs), which underperform on low-homology and orphan proteins. We introduce PLAME, a lightweight MSA design framework that leverages evolutionary embeddings from…

Machine Learning · Computer Science 2025-09-29 Hanqun Cao , Xinyi Zhou , Zijun Gao , Chenyu Wang , Xin Gao , Zhi Zhang , Cesar de la Fuente-Nunez , Chunbin Gu , Ge Liu , Pheng-Ann Heng

As one of the most popular and sought-after generative models in the recent years, diffusion models have sparked the interests of many researchers and steadily shown excellent advantage in various generative tasks such as image synthesis,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-17 Zhiyuan Ma , Yuzhu Zhang , Guoli Jia , Liangliang Zhao , Yichao Ma , Mingjie Ma , Gaofeng Liu , Kaiyan Zhang , Jianjun Li , Bowen Zhou

Fitting multi-exponential models to Diffusion MRI (dMRI) data has always been challenging due to various underlying complexities. In this work, we introduce a novel and robust fitting framework for the standard two-compartment IVIM…

To address the increasing need for efficient and accurate content moderation, we propose an efficient and lightweight deep classification ensemble structure. Our approach is based on a combination of simple visual features, designed for…

Computer Vision and Pattern Recognition · Computer Science 2023-09-12 Mohammad Hosseini , Mahmudul Hasan

Accurate and computationally efficient 3D medical image segmentation remains a critical challenge in clinical workflows. Transformer-based architectures often demonstrate superior global contextual modeling but at the expense of excessive…

Image and Video Processing · Electrical Eng. & Systems 2026-02-19 Kavyansh Tyagi , Vishwas Rathi , Puneet Goyal

In recent years, diffusion models, and more generally score-based deep generative models, have achieved remarkable success in various applications, including image and audio generation. In this paper, we view diffusion models as an implicit…

Statistics Theory · Mathematics 2026-02-12 Hyeok Kyu Kwon , Dongha Kim , Ilsang Ohn , Minwoo Chae

This study introduces a novel point-wise diffusion model that processes spatio-temporal points independently to efficiently predict complex physical systems with shape variations. This methodological contribution lies in applying forward…

Computational Physics · Physics 2025-08-05 Jiyong Kim , Sunwoong Yang , Namwoo Kang

We investigate methods to reduce inference time and memory footprint in stable diffusion models by introducing lightweight decoders for both image and video synthesis. Traditional latent diffusion pipelines rely on large Variational…

Computer Vision and Pattern Recognition · Computer Science 2025-03-10 Alexey Buzovkin , Evgeny Shilov

To detect salient objects accurately, existing methods usually design complex backbone network architectures to learn and fuse powerful features. However, the saliency inference module that performs saliency prediction from the fused…

Computer Vision and Pattern Recognition · Computer Science 2019-03-26 Zun Li , Congyan Lang , Yunpeng Chen , Junhao Liew , Jiashi Feng

This manuscript delves into the intersection of genomics and phenotypic prediction, focusing on the statistical innovation required to navigate the complexities introduced by noisy covariates and confounders. The primary emphasis is on the…

Methodology · Statistics 2024-11-15 Upama Paul Chowdhury , Ronit Bhattacharjee , Susmita Das , Abhik Ghosh

The automatic segmentation of blood vessels in fundus images can help analyze the condition of retinal vasculature, which is crucial for identifying various systemic diseases like hypertension, diabetes, etc. Despite the success of Deep…

Image and Video Processing · Electrical Eng. & Systems 2023-04-26 Ashish Kumar , R. K. Agrawal , Leve Joseph

How can we find a subset of training samples that are most responsible for a specific prediction made by a complex black-box machine learning model? More generally, how can we explain the model's decisions to end-users in a transparent way?…

Machine Learning · Computer Science 2021-06-22 Xing Han , Joydeep Ghosh

Diffusion probabilistic models have generated high quality image synthesis recently. However, one pain point is the notorious inference to gradually obtain clear images with thousands of steps, which is time consuming compared to other…

Computer Vision and Pattern Recognition · Computer Science 2023-01-04 Gang Chen

Diffusion models have achieved remarkable success in high-fidelity image generation but remain computationally demanding due to their multi-step denoising process and large model sizes. Although prior work improves efficiency either by…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Zongfang Liu , Shengkun Tang , Zongliang Wu , Xin Yuan , Zhiqiang Shen

Masked image modeling (MIM) pre-training for large-scale vision transformers (ViTs) has enabled promising downstream performance on top of the learned self-supervised ViT features. In this paper, we question if the \textit{extremely simple}…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Jin Gao , Shubo Lin , Shaoru Wang , Yutong Kou , Zeming Li , Liang Li , Congxuan Zhang , Xiaoqin Zhang , Yizheng Wang , Weiming Hu

Diffusion models have shown remarkable performance in generation problems over various domains including images, videos, text, and audio. A practical bottleneck of diffusion models is their sampling speed, due to the repeated evaluation of…

Computer Vision and Pattern Recognition · Computer Science 2024-08-13 Taehong Moon , Moonseok Choi , EungGu Yun , Jongmin Yoon , Gayoung Lee , Jaewoong Cho , Juho Lee

Traditional ML inference is evolving toward modeless inference, which abstracts the complexity of model selection from users, allowing the system to automatically choose the most appropriate model for each request based on accuracy and…

Systems and Control · Electrical Eng. & Systems 2025-01-16 ChonLam Lao , Jiaqi Gao , Ganesh Ananthanarayanan , Aditya Akella , Minlan Yu

Diffusion models have recently achieved remarkable performance in image super-resolution (SR), but their high computational cost limits practical deployment in remote sensing applications. To address this issue, we propose SlimDiffSR, a…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Ce Wang , Zhenyu Hu , Wanjie Sun

We study inference-time scaling for diffusion models, where the goal is to adapt a pre-trained model to new target distributions without retraining. Existing guidance-based methods are simple but introduce bias, while particle-based…

Machine Learning · Computer Science 2026-02-24 Yinuo Ren , Wenhao Gao , Lexing Ying , Grant M. Rotskoff , Jiequn Han

In robotics applications, few-shot segmentation is crucial because it allows robots to perform complex tasks with minimal training data, facilitating their adaptation to diverse, real-world environments. However, pixel-level annotations of…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Florent Chiaroni , Ali Ayub , Ola Ahmad