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In this article, we report an imaging method, termed Fourier ptychographic microscopy (FPM), which iteratively stitches together a number of variably illuminated, low-resolution intensity images in Fourier space to produce a wide-field,…

Optics · Physics 2014-05-02 Guoan Zheng , Roarke Horstmeyer , Changhuei Yang

Deep learning model effectiveness in classification tasks is often challenged by the quality and quantity of training data whenever they are affected by strong spurious correlations between specific attributes and target labels. This…

With the installation of next-generation phased array feed (PAF) receivers on radio telescopes, there is an urgent need to develop effective and computationally efficient radio frequency interference (RFI) mitigation methods for large-scale…

Instrumentation and Methods for Astrophysics · Physics 2026-01-21 Juntao Bai , Shi Dai , Na Wang , Stefan Osłowski , Shuangqiang Wang , George Hobbs , Jianping Yuan , Wenming Yan , Qijun Zhi , Lunhua Shang , Xin Xu , Shijun Dang , De Zhao

In this work, we propose a novel unsupervised deep learning model to address multi-focus image fusion problem. First, we train an encoder-decoder network in unsupervised manner to acquire deep feature of input images. And then we utilize…

Computer Vision and Pattern Recognition · Computer Science 2020-09-25 Boyuan Ma , Xiaojuan Ban , Haiyou Huang , Yu Zhu

Deformable image registration aims to precisely align medical images from different modalities or times. Traditional deep learning methods, while effective, often lack interpretability, real-time observability and adjustment capacity during…

Computer Vision and Pattern Recognition · Computer Science 2024-10-08 Yongtai Zhuo , Yiqing Shen

Quantitative phase imaging (QPI) has been widely applied in characterizing cells and tissues. Spatial light interference microscopy (SLIM) is a highly sensitive QPI method, due to its partially coherent illumination and common path…

Image and Video Processing · Electrical Eng. & Systems 2024-06-12 Yuheng Jiao , Yuchen R. He , Mikhail E. Kandel , Xiaojun Liu , Wenlong Lu , Gabriel Popescu

Multifocal plane microscopy (MUM) allows three dimensional objects to be imaged in a single camera frame. Our approach uses dual orthogonal diffraction phase gratings with a quadratic distortion of the lines to apply defocus to the first…

Optics · Physics 2020-03-13 Benjamin Gore , Noah Schwartz , Paul Dalgarno

In order to measure the radial displacements of facets on surface of a growing spherical Cu_{2-\delta}Se crystal with sub-nanometer resolution, we have investigated the reliability and accuracy of standard method of Fourier analysis of…

Optics · Physics 2009-11-13 Jadranko Gladic , Zlatko Vucic , Davorin Lovric

Image denoising stands as a critical challenge in image processing and computer vision, aiming to restore the original image from noise-affected versions caused by various intrinsic and extrinsic factors. This process is essential for…

Image and Video Processing · Electrical Eng. & Systems 2024-03-19 Peter Luvton , Alfredo Castillejos , Jim Zhao , Christina Chajo

Sample-induced aberrations and optical imperfections limit the resolution of fluorescence microscopy. Phase diversity is a powerful technique that leverages complementary phase information in sequentially acquired images with deliberately…

Synthetic aperture imaging has enabled breakthrough observations from radar to astronomy. However, optical implementation remains challenging due to stringent wavefield synchronization requirements among multiple receivers. Here we present…

Poor access to eye care is a major global challenge that could be ameliorated by low-cost, portable, and easy-to-use diagnostic technologies. Diffuser-based imaging has the potential to enable inexpensive, compact optical systems that can…

Medical Physics · Physics 2020-06-23 Yunzhe Li , Gregory N. McKay , Nicholas J. Durr , Lei Tian

In this paper we present an interference detection toolbox consisting of a high dynamic range Digital Fast-Fourier-Transform spectrometer (DFFT, based on FPGA-technology) and data analysis software for automated radio frequency interference…

Astrophysics · Physics 2007-05-23 Benjamin Winkel , Juergen Kerp , Stephan Stanko

A widely tested approach to overcoming the diffraction limit in microscopy without disturbing the sample relies on substituting widefield sample illumination with a structured light beam. This gives rise to confocal, image-scanning and…

Optics · Physics 2024-06-03 Alexander Duplinskiy , Jernej Frank , Kaden Bearne , A. I. Lvovsky

The optical diffraction limit, formulated by Abbe 140 years ago, imposes a bound on imaging resolution in classical optics. Over the last twenty years, many theoretical schemes have been presented for overcoming the diffraction barrier in…

Quantum Physics · Physics 2013-07-12 O. Schwartz , J. M. Levitt , R. Tenne , S. Itzhakov , Z. Deutsch , D. Oron

Diffraction-limited focusing deep into biological tissue is challenging due to spherical aberrations that lead to a broadening of the focal spot particularly in axial direction. While the diffraction-limit can be restored employing…

We report on a matrix-based diffraction integral that evaluates the focal field of any diffraction-limited axisymmetric complex system. This diffraction formula is a generalization of the Debye integral applied to apertured focused beams,…

Optics · Physics 2015-06-26 Carlos J. Zapata-Rodriguez

Fourier ptychography (FP) imaging, drawing on the idea of synthetic aperture, has been demonstrated as a potential approach for remote sub-diffraction-limited imaging. Nevertheless, the farthest imaging distance is still limited around 10 m…

Fluorescence microscopy has enabled a dramatic development in modern biology by visualizing biological organisms with micrometer scale resolution. However, due to the diffraction limit, sub-micron/nanometer features are difficult to…

Image and Video Processing · Electrical Eng. & Systems 2021-03-10 Varun Mannam , Yide Zhang , Xiaotong Yuan , Scott Howard

Optical microrobots actuated by optical tweezers (OT) are important for cell manipulation and microscale assembly, but their autonomous operation depends on accurate 3D perception. Developing such perception systems is challenging because…

Robotics · Computer Science 2026-04-14 Lan Wei , Zongcai Tan , Kangyi Lu , Jian-Qing Zheng , Dandan Zhang