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This paper introduces the combination of Laser-induced breakdown spectroscopy (LIBS), Raman spectroscopy (RS) and diffuse reflectance spectroscopy (DRS) in the field of biomedical research. Thereby, the results from RS and LIBS are combined…

We present a method that takes as input a single dual-pixel image, and simultaneously estimates the image's defocus map -- the amount of defocus blur at each pixel -- and recovers an all-in-focus image. Our method is inspired from recent…

Computer Vision and Pattern Recognition · Computer Science 2021-10-13 Shumian Xin , Neal Wadhwa , Tianfan Xue , Jonathan T. Barron , Pratul P. Srinivasan , Jiawen Chen , Ioannis Gkioulekas , Rahul Garg

The depth-of-field (DoF) effect, which introduces aesthetically pleasing blur, enhances photographic quality but is fixed and difficult to modify once the image has been created. This becomes problematic when the applied blur is…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Yiyang Wang , Xi Chen , Xiaogang Xu , Yu Liu , Hengshuang Zhao

We developed a multifocus optical-resolution photoacoustic microscope (MPAM) with extended depth of field (DoF) by using a tunable acoustic gradient (TAG) lens and a pulse delay method. TAG lens is designed to control the divergence angle…

Optics · Physics 2020-09-09 Xianlin Song

We report a computational 3D microscopy technique, termed Fourier ptychographic diffraction tomography (FPDT), that iteratively stitches together numerous variably illuminated, low-resolution images acquired with a low-numerical aperture…

Optics · Physics 2020-02-19 Chao Zuo , Jiasong Sun , Jiaji Li , Anand Asundi , Qian Chen

We present a widefield fluorescence microscope that integrates an event-based image sensor (EBIS) with a CMOS image sensor (CIS) for ultra-fast microscopy with spectral distinction capabilities. The EBIS achieves temporal resolution of…

Optics · Physics 2024-10-22 Richard G. Baird , Apratim Majumder , Rajesh Menon

High-resolution imaging of ultracold atoms typically requires custom high numerical aperture (NA) optics, as is the case for quantum gas microscopy. These high NA objectives involve many optical elements each of which contributes to loss…

Quantum Gases · Physics 2021-11-01 Emine Altuntas , Ian B. Spielman

Multimodal 3D MRI brain tumor segmentation is a pivotal step in radiotherapy target delineation, surgical planning and post-treatment assessment. Existing methods often assume artifact-free MRI images. However, inevitable patient motion…

Image and Video Processing · Electrical Eng. & Systems 2026-05-18 Yuchun Wang , Xiaosong Li , Gefei Liang , Yang Liu

For several centuries, far-field optical microscopy has remained a key instrument in many scientific disciplines including physical, chemical and biomedical research. Nonetheless, far-field imaging has many limitations: the spatial…

Optics · Physics 2020-01-27 Lyubov V. Amitonova , Johannes F. de Boer

A Deformable Mirror (DM) is an important component of an Adaptive Optics system. It is known that an on-axis spherical/parabolic optical component, placed at an angle to the incident beam introduces defocus as well as astigmatism in the…

Scanning near-field optical microscopy is one of the most effective techniques for spectroscopy of nanoscale systems. However, inferring optical constants from the measured near-field signal can be challenging because of a complicated and…

Optics · Physics 2023-04-19 Yueqi Zhao , Xinzhong Chen , Ziheng Yao , Mengkun Liu , Michael M. Fogler

The scarcity of annotated surgical data poses a significant challenge for developing deep learning systems in computer-assisted interventions. While diffusion models can synthesize realistic images, they often suffer from data memorization,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Danush Kumar Venkatesh , Stefanie Speidel

Multi-focus image fusion is a technique for obtaining an all-in-focus image in which all objects are in focus to extend the limited depth of field (DoF) of an imaging system. Different from traditional RGB-based methods, this paper presents…

Computer Vision and Pattern Recognition · Computer Science 2018-06-06 Hang Liu , Hengyu Li , Jun Luo , Shaorong Xie , Yu Sun

Digital aberration measurement and removal play a prominent role in computational imaging platforms aimed at achieving simple and compact optical arrangements. A recent important class of such platforms is Fourier ptychography, which is…

Image processing and edge detection are at the core of several newly emerging technologies, such as augmented reality, autonomous driving and more generally object recognition. Image processing is typically performed digitally using…

The rapid proliferation of AI-generated visual media has created an urgent need for efficient, trustworthy deepfake detection systems. However, existing deep learning-based detection methods rely on computationally intensive and…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Parnian Ghapandar Kashani , Shiqi Chen , Aydogan Ozcan

Following the increasing trends of malicious applications or cyber threats in general, program analysis has become a ubiquitous technique in extracting relevant features. The current state-of-the-art solutions seem to fall behind new…

Cryptography and Security · Computer Science 2023-06-26 Vlad Crăciun , Andrei Mogage , Dorel Lucanu

Facial recognition systems have achieved remarkable success by leveraging deep neural networks, advanced loss functions, and large-scale datasets. However, their performance often deteriorates in real-world scenarios involving low-quality…

Computer Vision and Pattern Recognition · Computer Science 2025-10-29 Sadaf Gulshad , Abdullah Aldahlawi

In optical imaging, achieving high resolution often comes at the expense of a shallow depth of field. This means that when using a standard microscope, any minor movement of the object along the optical axis can cause the image to become…

High-throughput biological imaging is often constrained by a trade-off between acquisition speed and image quality. Fast imaging modalities, such as wide-field fluorescence microscopy, enable large-scale data acquisition but suffer from…

Image and Video Processing · Electrical Eng. & Systems 2026-04-20 Dominik Panek , Carina Rząca , Maksymilian Szczypior , Joanna Sorysz , Krzysztof Misztal , Zbigniew Baster , Zenon Rajfur