Related papers: TextOmics-Guided Diffusion for Hit-like Molecular …
3D generative models have shown significant promise in structure-based drug design (SBDD), particularly in discovering ligands tailored to specific target binding sites. Existing algorithms often focus primarily on ligand-target binding,…
Generating molecular structures with desired properties is a critical task with broad applications in drug discovery and materials design. We propose 3M-Diffusion, a novel multi-modal molecular graph generation method, to generate diverse,…
Diffusion models have become a new generative paradigm for text generation. Considering the discrete categorical nature of text, in this paper, we propose GlyphDiffusion, a novel diffusion approach for text generation via text-guided image…
Text-to-image (T2I) diffusion models have drawn attention for their ability to generate high-quality images with precise text alignment. However, these models can also be misused to produce inappropriate content. Existing safety measures,…
Diffusion Probabilistic Models (DPMs) have demonstrated significant potential in 3D medical image segmentation tasks. However, their high computational cost and inability to fully capture global 3D contextual information limit their…
Molecule generation is a very important practical problem, with uses in drug discovery and material design, and AI methods promise to provide useful solutions. However, existing methods for molecule generation focus either on 2D graph…
The rapid advancement of Text-to-Image(T2I) generative models has enabled the synthesis of high-quality images guided by textual descriptions. Despite this significant progress, these models are often susceptible in generating contents that…
In recent years, image generation has shown a great leap in performance, where diffusion models play a central role. Although generating high-quality images, such models are mainly conditioned on textual descriptions. This begs the…
Diffusion models have been successful on a range of conditional generation tasks including molecular design and text-to-image generation. However, these achievements have primarily depended on task-specific conditional training or…
Text-to-image diffusion models have demonstrated an impressive ability to produce high-quality outputs. However, they often struggle to accurately follow fine-grained spatial information in an input text. To this end, we propose a…
Recent text-to-image (T2I) diffusion models show outstanding performance in generating high-quality images conditioned on textual prompts. However, they fail to semantically align the generated images with the prompts due to their limited…
Large diffusion-based Text-to-Image (T2I) models have shown impressive generative powers for text-to-image generation as well as spatially conditioned image generation. For most applications, we can train the model end-toend with paired…
Generating molecules that bind to specific proteins is an important but challenging task in drug discovery. Previous works usually generate atoms in an auto-regressive way, where element types and 3D coordinates of atoms are generated one…
We present TokenCompose, a Latent Diffusion Model for text-to-image generation that achieves enhanced consistency between user-specified text prompts and model-generated images. Despite its tremendous success, the standard denoising process…
Diffusion models have attracted significant attention due to the remarkable ability to create content and generate data for tasks like image classification. However, the usage of diffusion models to generate the high-quality object…
Diffusion-based generative models have shown promise in synthesizing histopathology images to address data scarcity caused by privacy constraints. Diagnostic text reports provide high-level semantic descriptions, and masks offer…
Large-scale text-to-image (T2I) diffusion models have showcased incredible capabilities in generating coherent images based on textual descriptions, enabling vast applications in content generation. While recent advancements have introduced…
Deep learning models for skin disease classification require large, diverse, and well-annotated datasets. However, such resources are often limited due to privacy concerns, high annotation costs, and insufficient demographic representation.…
The acquisition of annotated datasets with paired images and segmentation masks is a critical challenge in domains such as medical imaging, remote sensing, and computer vision. Manual annotation demands significant resources, faces ethical…
Aside from offering state-of-the-art performance in medical image generation, denoising diffusion probabilistic models (DPM) can also serve as a representation learner to capture semantic information and potentially be used as an image…