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Large language models (LLMs) have demonstrated strong performance on medical benchmarks, including question answering and diagnosis. To enable their use in clinical settings, LLMs are typically further adapted through continued pretraining…

Thematic analysis (TA) is a widely used qualitative approach for uncovering latent meanings in unstructured text data. TA provides valuable insights in healthcare but is resource-intensive. Large Language Models (LLMs) have been introduced…

Human-Computer Interaction · Computer Science 2025-03-27 Huimin Xu , Seungjun Yi , Terence Lim , Jiawei Xu , Andrew Well , Carlos Mery , Aidong Zhang , Yuji Zhang , Heng Ji , Keshav Pingali , Yan Leng , Ying Ding

The advent of large language models (LLMs) has opened new avenues for analyzing complex, unstructured data, particularly within the medical domain. Electronic Health Records (EHRs) contain a wealth of information in various formats,…

Information Retrieval · Computer Science 2025-06-10 Wu Hao Ran , Xi Xi , Furong Li , Jingyi Lu , Jian Jiang , Hui Huang , Yuzhuan Zhang , Shi Li

Passively collected behavioral health data from ubiquitous sensors holds significant promise to provide mental health professionals insights from patient's daily lives; however, developing analysis tools to use this data in clinical…

Clinical trial matching is a key process in health delivery and discovery. In practice, it is plagued by overwhelming unstructured data and unscalable manual processing. In this paper, we conduct a systematic study on scaling clinical trial…

The application of Artificial Intelligence (AI) in healthcare has been revolutionary, especially with the recent advancements in transformer-based Large Language Models (LLMs). However, the task of understanding unstructured electronic…

Computation and Language · Computer Science 2023-08-08 Shivani Shekhar , Simran Tiwari , T. C. Rensink , Ramy Eskander , Wael Salloum

The biomedical field relies heavily on concept linking in various areas such as literature mining, graph alignment, information retrieval, question-answering, data, and knowledge integration. Although large language models (LLMs) have made…

Computation and Language · Computer Science 2023-07-04 Qinyong Wang , Zhenxiang Gao , Rong Xu

Large language models have exhibited exceptional performance on various Natural Language Processing (NLP) tasks, leveraging techniques such as the pre-training, and instruction fine-tuning. Despite these advances, their effectiveness in…

Computation and Language · Computer Science 2023-06-19 Guangyu Wang , Guoxing Yang , Zongxin Du , Longjun Fan , Xiaohu Li

Large Language Models (LLMs) have rapidly become important tools in Biomedical and Health Informatics (BHI), enabling new ways to analyze data, treat patients, and conduct research. This study aims to provide a comprehensive overview of LLM…

Digital Libraries · Computer Science 2024-07-30 Huizi Yu , Lizhou Fan , Lingyao Li , Jiayan Zhou , Zihui Ma , Lu Xian , Wenyue Hua , Sijia He , Mingyu Jin , Yongfeng Zhang , Ashvin Gandhi , Xin Ma

This study introduces a novel unsupervised approach for separating overlapping heart and lung sounds using variational autoencoders (VAEs). In clinical settings, these sounds often interfere with each other, making manual separation…

Audio and Speech Processing · Electrical Eng. & Systems 2025-06-24 Yasaman Torabi , Shahram Shirani , James P. Reilly

This study investigates a hybrid method for text classification that integrates deep feature extraction from large language models, multi-scale fusion through feature pyramids, and structured modeling with graph neural networks to enhance…

Computation and Language · Computer Science 2025-11-11 Xiangchen Song , Yulin Huang , Jinxu Guo , Yuchen Liu , Yaxuan Luan

General audio understanding is a fundamental goal for large audio-language models, with audio captioning serving as a cornerstone task for their development. However, progress in this domain is hindered by existing datasets, which lack the…

Audio and Speech Processing · Electrical Eng. & Systems 2026-03-26 Yadong Niu , Tianzi Wang , Heinrich Dinkel , Xingwei Sun , Jiahao Zhou , Gang Li , Jizhong Liu , Junbo Zhang , Jian Luan

Multi-speaker automatic speech recognition (MS-ASR) faces significant challenges in transcribing overlapped speech, a task critical for applications like meeting transcription and conversational analysis. While serialized output training…

Audio and Speech Processing · Electrical Eng. & Systems 2025-06-09 Yuke Lin , Ming Cheng , Ze Li , Beilong Tang , Ming Li

We explore a lightweight framework that adapts frozen large language models to analyze longitudinal clinical data. The approach integrates patient history and context within the language model space to generate accurate forecasts without…

Computation and Language · Computer Science 2025-10-29 Tananun Songdechakraiwut , Michael Lutz

Large Language Models have undoubtedly revolutionized the Natural Language Processing field, the current trend being to promote one-model-for-all tasks (sentiment analysis, translation, etc.). However, the statistical mechanisms at work in…

Computation and Language · Computer Science 2024-08-26 Célia D'Cruz , Jean-Marc Bereder , Frédéric Precioso , Michel Riveill

Large language models applied to vast biological datasets have the potential to transform biology by uncovering disease mechanisms and accelerating drug development. However, current models are often siloed, trained separately on…

Large Audio-Language Models (LALMs) perform well on audio understanding tasks but lack multistep reasoning and tool-calling found in recent Large Language Models (LLMs). This paper presents AudioToolAgent, a framework that coordinates…

Sound · Computer Science 2026-02-16 Gijs Wijngaard , Elia Formisano , Michel Dumontier , Jenia Jitsev

We introduce AudioPaLM, a large language model for speech understanding and generation. AudioPaLM fuses text-based and speech-based language models, PaLM-2 [Anil et al., 2023] and AudioLM [Borsos et al., 2022], into a unified multimodal…

The aim of this study is to implement a method to remove ambient noise in biomedical sounds captured in auscultation. We propose an incremental approach based on multichannel non-negative matrix partial co-factorization (NMPCF) for ambient…

Speech data has rich acoustic and paralinguistic information with important cues for understanding a speaker's tone, emotion, and intent, yet traditional large language models such as BERT do not incorporate this information. There has been…

Computation and Language · Computer Science 2023-11-14 Fatema Hasan , Yulong Li , James Foulds , Shimei Pan , Bishwaranjan Bhattacharjee