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Accurately interpreting cardiac auscultation signals plays a crucial role in diagnosing and managing cardiovascular diseases. However, the paucity of labelled data inhibits classification models' training. Researchers have turned to…

Sound · Computer Science 2025-06-18 Leigh Abbott , Milan Marocchi , Matthew Fynn , Yue Rong , Sven Nordholm

This paper tackles two major problem settings for interpretability of audio processing networks, post-hoc and by-design interpretation. For post-hoc interpretation, we aim to interpret decisions of a network in terms of high-level audio…

Large Language Models (LLMs) have swiftly emerged as vital resources for different applications in the biomedical and healthcare domains; however, these models encounter issues such as generating inaccurate information or hallucinations.…

Computation and Language · Computer Science 2024-05-06 Mingchen Li , Halil Kilicoglu , Hua Xu , Rui Zhang

We propose a method for noise reduction, the task of producing a clean audio signal from a recording corrupted by additive noise. Many common approaches to this problem are based upon applying non-negative matrix factorization to…

Audio and Speech Processing · Electrical Eng. & Systems 2021-10-08 Andrew Sack , Wenzhao Jiang , Michael Perlmutter , Palina Salanevich , Deanna Needell

Mental health is increasingly critical in contemporary healthcare, with psychotherapy demanding dynamic, context-sensitive interactions that traditional NLP methods struggle to capture. Large Language Models (LLMs) offer significant…

Computation and Language · Computer Science 2025-06-30 Hongbin Na , Yining Hua , Zimu Wang , Tao Shen , Beibei Yu , Lilin Wang , Wei Wang , John Torous , Ling Chen

Large language models (LLMs) can capture rich representations of concepts that are useful for real-world tasks. However, language alone is limited. While existing LLMs excel at text-based inferences, health applications require that models…

Computation and Language · Computer Science 2023-05-26 Xin Liu , Daniel McDuff , Geza Kovacs , Isaac Galatzer-Levy , Jacob Sunshine , Jiening Zhan , Ming-Zher Poh , Shun Liao , Paolo Di Achille , Shwetak Patel

This paper conducts a comprehensive investigation into applying large language models, particularly on BioBERT, in healthcare. It begins with thoroughly examining previous natural language processing (NLP) approaches in healthcare, shedding…

Artificial Intelligence · Computer Science 2023-10-13 Shyni Sharaf , V. S. Anoop

Clinical decision-making requires reasoning over incomplete, imprecise, and linguistically expressed patient narratives. While large language models (LLMs) excel at extracting latent information from natural language, they lack the…

Artificial Intelligence · Computer Science 2026-05-26 Xiaoyang Fan , Yufan Cai , Zhe Hou , Jin Song Dong

Medical image registration is an essential topic in medical image analysis. In this paper, we propose a method for medical image registration using a pretrained large language model. We find that using the pretrained large language model to…

Computer Vision and Pattern Recognition · Computer Science 2024-05-30 Mingrui Ma , Yu Yang

Auscultation is a vital diagnostic tool, yet its utility is often limited by subjective interpretation. While general-purpose Audio-Language Models (ALMs) excel in general domains, they struggle with the nuances of physiological signals. We…

High-quality, large-scale data is essential for robust deep learning models in medical applications, particularly ultrasound image analysis. Diffusion models facilitate high-fidelity medical image generation, reducing the costs associated…

Image and Video Processing · Electrical Eng. & Systems 2024-04-01 Pooria Ashrafian , Milad Yazdani , Moein Heidari , Dena Shahriari , Ilker Hacihaliloglu

In most current approaches of speech processing, information is extracted from the magnitude spectrum. However recent perceptual studies have underlined the importance of the phase component. The goal of this paper is to investigate the…

Sound · Computer Science 2020-01-03 Thomas Drugman , Thomas Dubuisson , Thierry Dutoit

Recent advances in artificial intelligence, particularly large language models LLMs, have shown promising capabilities in transforming rare disease research. This survey paper explores the integration of LLMs in the analysis of rare…

Computation and Language · Computer Science 2025-05-26 Valentina Carbonari , Pierangelo Veltri , Pietro Hiram Guzzi

Various informative factors mixed in speech signals, leading to great difficulty when decoding any of the factors. An intuitive idea is to factorize each speech frame into individual informative factors, though it turns out to be highly…

Audio and Speech Processing · Electrical Eng. & Systems 2018-03-05 Lantian Li , Dong Wang , Yixiang Chen , Ying Shi , Zhiyuan Tang , Thomas Fang Zheng

The rapid advancement of large language models (LLMs) has opened new boundaries in the extraction and synthesis of medical knowledge, particularly within evidence synthesis. This paper reviews the state-of-the-art applications of LLMs in…

Large language models are a form of artificial intelligence systems whose primary knowledge consists of the statistical patterns, semantic relationships, and syntactical structures of language1. Despite their limited forms of "knowledge",…

Artificial Intelligence · Computer Science 2023-10-13 Yizhen Zheng , Huan Yee Koh , Jiaxin Ju , Anh T. N. Nguyen , Lauren T. May , Geoffrey I. Webb , Shirui Pan

Automatic disease diagnosis has become increasingly valuable in clinical practice. The advent of large language models (LLMs) has catalyzed a paradigm shift in artificial intelligence, with growing evidence supporting the efficacy of LLMs…

Patient-trial matching requires reasoning over long, heterogeneous electronic health records (EHRs) and complex eligibility criteria, posing significant challenges for scalability, generalization, and computational efficiency. Existing…

Computation and Language · Computer Science 2026-04-27 Xiaodi Li , Yang Xiao , Munhwan Lee , Konstantinos Leventakos , Young J. Juhn , David Jones , Terence T. Sio , Wei Liu , Maria Vassilaki , Nansu Zong

Europe's healthcare systems require enhanced interoperability and digitalization, driving a demand for innovative solutions to process legacy clinical data. This paper presents the results of our project, which aims to leverage Large…

Computation and Language · Computer Science 2025-07-09 Aynur Guluzade , Naguib Heiba , Zeyd Boukhers , Florim Hamiti , Jahid Hasan Polash , Yehya Mohamad , Carlos A Velasco

Large Language Models have advanced clinical text classification, but their opaque predictions remain a critical barrier to practical adoption in research and clinical settings where investigators and physicians need to understand which…

Computation and Language · Computer Science 2025-11-18 Karthikeyan K , Raghuveer Thirukovalluru , David Carlson