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Liver diseases are a serious health concern in the world, which requires precise and timely diagnosis to enhance the survival chances of patients. The current literature implemented numerous machine learning and deep learning models to…

Leukemia, the cancer of blood cells, originates in the blood-forming cells of the bone marrow. In Chronic Myeloid Leukemia (CML) conditions, the cells partially become mature that look like normal white blood cells but do not resist…

Genomics · Quantitative Biology 2023-02-09 Madiha Hameed , Muhammad Bilal , Tuba Majid , Abdul Majid , Asifullah Khan

Automated red blood cell (RBC) classification on blood smear images helps hematologists to analyze RBC lab results in a reduced time and cost. However, overlapping cells can cause incorrect predicted results, and so they have to be…

Image and Video Processing · Electrical Eng. & Systems 2024-10-30 Korranat Naruenatthanaset , Thanarat H. Chalidabhongse , Duangdao Palasuwan , Nantheera Anantrasirichai , Attakorn Palasuwan

N-glycosylation is a critical quality attribute of monoclonal antibodies (mAbs), the dominant class of biopharmaceuticals. Controlling glycosylation remains difficult due to intrinsic pathway complexity, limited online measurements, and a…

Optimization and Control · Mathematics 2026-02-03 Yingjie Ma , Jing Guo , Alexis B. Dubs , Krystian K. Ganko , Richard D. Braatz

The classification of white blood cells (WBCs) from peripheral blood smears is critical for the diagnosis of leukemia. However, automated approaches still struggle due to challenges including class imbalance, domain shift, and morphological…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Antony Gitau , Martin Paulson , Bjørn-Jostein Singstad , Karl Thomas Hjelmervik , Ola Marius Lysaker , Veralia Gabriela Sanchez

The unpredictability of seizures continues to distress many people with drug-resistant epilepsy. On account of recent technological advances, considerable efforts have been made using different hardware technologies to realize smart devices…

Emerging Technologies · Computer Science 2022-02-21 Corey Lammie , Wei Xiang , Mostafa Rahimi Azghadi

Semi-supervised techniques have removed the barriers of large scale labelled set by exploiting unlabelled data to improve the performance of a model. In this paper, we propose a semi-supervised deep multi-task classification and…

Computer Vision and Pattern Recognition · Computer Science 2020-08-12 R. M. Saad Bashir , Talha Qaiser , Shan E Ahmed Raza , Nasir M. Rajpoot

Detecting and delineating tiny targets in 3D brain scans is a central yet under-addressed challenge in medical imaging.In ischemic stroke, for instance, the culprit thrombus is small, low-contrast, and variably expressed across…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Sofia Vargas-Ibarra , Vincent Vigneron , Hichem Maaref , Sonia Garcia-Salicetti

The process of identifying and characterizing B-cell epitopes, which are the portions of antigens recognized by antibodies, is important for our understanding of the immune system, and for many applications including vaccine development,…

Quantitative Methods · Quantitative Biology 2025-12-10 Xiao Yuan

Antimicrobial resistance (AMR) is projected to cause up to 10 million deaths annually by 2050, underscoring the urgent need for new antibiotics. Here we present ApexAmphion, a deep-learning framework for de novo design of antibiotics that…

Acute Lymphoblastic Leukemia (ALL) is one of the most common types of childhood blood cancer. The quick start of the treatment process is critical to saving the patient's life, and for this reason, early diagnosis of this disease is…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Amirhossein Askari Farsangi , Ali Sharifi-Zarchi , Mohammad Hossein Rohban

Cross-Entropy Method (CEM) is commonly used for planning in model-based reinforcement learning (MBRL) where a centralized approach is typically utilized to update the sampling distribution based on only the top-$k$ operation's results on…

Machine Learning · Computer Science 2022-12-19 Zichen Zhang , Jun Jin , Martin Jagersand , Jun Luo , Dale Schuurmans

Hypertrophic cardiomyopathy (HCM) patients have a high incidence of atrial fibrillation (AF) and increased stroke risk, even with low risk of congestive heart failure, hypertension, age, diabetes, previous stroke/transient ischemic attack…

Elucidating exocytosis processes provide insights into cellular neurotransmission mechanisms, and may have potential in neurodegenerative diseases research. Amperometry is an established electrochemical method for the detection of…

Subcellular Processes · Quantitative Biology 2023-02-07 Jeyashree Krishnan , Zeyu Lian , Pieter E. Oomen , Xiulan He , Soodabeh Majdi , Andreas Schuppert , Andrew Ewing

Timely and accurate lymphoma diagnosis is essential for guiding cancer treatment. Standard diagnostic practice combines hematoxylin and eosin (HE)-stained whole slide images with immunohistochemistry, flow cytometry, and molecular genetic…

Significant advancements in type 1 diabetes treatment have been made in the development of state-of-the-art Artificial Pancreas Systems (APS). However, lapses currently exist in the timely treatment of unsafe blood glucose (BG) levels,…

Machine Learning · Computer Science 2023-03-20 Chloe Smith , Maxfield Kouzel , Xugui Zhou , Homa Alemzadeh

This paper presents a feasibility study demonstrating that quantum machine learning (QML) algorithms achieve competitive performance on real-world medical imaging despite operating under severe constraints. We evaluate Equilibrium…

Emerging Technologies · Computer Science 2026-01-27 A. Bano , L. Liebovitch

Objective: Peritoneal Dialysis (PD) is one of the most widely used life-supporting therapies for patients with End-Stage Renal Disease (ESRD). Predicting mortality risk and identifying modifiable risk factors based on the Electronic Medical…

Machine Learning · Computer Science 2023-02-09 Liantao Ma , Chaohe Zhang , Junyi Gao , Xianfeng Jiao , Zhihao Yu , Xinyu Ma , Yasha Wang , Wen Tang , Xinju Zhao , Wenjie Ruan , Tao Wang

Background: To develop an artificial intelligence system that can accurately identify acute non-traumatic intracranial hemorrhage (ICH) etiology based on non-contrast CT (NCCT) scans and investigate whether clinicians can benefit from it in…

Image and Video Processing · Electrical Eng. & Systems 2023-02-03 Meng Zhao , Yifan Hu , Ruixuan Jiang , Yuanli Zhao , Dong Zhang , Yan Zhang , Rong Wang , Yong Cao , Qian Zhang , Yonggang Ma , Jiaxi Li , Shaochen Yu , Wenjie Li , Ran Zhang , Yefeng Zheng , Shuo Wang , Jizong Zhao

Semblance velocity analysis is a crucial step in seismic data processing. To avoid the huge time-cost when performed manually, some deep learning methods are proposed for automatic semblance velocity picking. However, the application of…

Geophysics · Physics 2022-07-04 Chenyu Qiu , Bangyu Wu , Meng Li , Hui Yang , Xu Zhu