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Conventional microscope objective lenses are diffraction limited, which means that they cannot resolve features smaller than half the illumination wavelength. Under white light illumination, such resolution limit is about 250-300 nm for an…
Fast and sensitive detector arrays enable image scanning microscopy (ISM), overcoming the trade-off between spatial resolution and signal-to-noise ratio (SNR) typical of confocal microscopy. However, current ISM approaches cannot provide…
Super-resolution fluorescence microscopy is an important tool in biomedical research for its ability to discern features smaller than the diffraction limit. However, due to its difficult implementation and high cost, the universal…
Hyperspectral images enable precise identification of ground objects by capturing their spectral signatures with fine spectral resolution.While high spatial resolution further enhances this capability, increasing spatial resolution through…
Wide-angle optical functionality is crucial for implementation of advanced imaging and image projection devices. Conventionally, wide-angle operation is attained by complicated assembly of multiple optical elements. Recent advances in…
Lightsheet microscopy is a powerful 3-D imaging technique that addresses limitations of traditional optical and confocal microscopy but suffers from a low penetration depth and reduced image quality at greater depths. Multiview lightsheet…
Single-view novel view synthesis (NVS), the task of generating images from new viewpoints based on a single reference image, is important but challenging in computer vision. Recent advancements in NVS have leveraged Denoising Diffusion…
We report an inverse-designed, high numerical aperture (~0.44), extended depth of focus (EDOF) meta-optic, which exhibit a lens-like point spread function (PSF). The EDOF meta-optic maintains a focusing efficiency comparable to that of a…
We present a novel structured light technique that uses Single Photon Avalanche Diode (SPAD) arrays to enable 3D scanning at high-frame rates and low-light levels. This technique, called "Single-Photon Structured Light", works by sensing…
Autofocus (AF) methods are extensively used in biomicroscopy, for example to acquire timelapses, where the imaged objects tend to drift out of focus. AD algorithms determine an optimal distance by which to move the sample back into the…
Dark-field X-ray imaging visualizes structural inhomogeneities through small-angle scattering, but existing directional methods are confined to the micrometer scale. While recent advances have extended dark-field capabilities to nanoscale…
We demonstrate a motion-free intensity diffraction tomography technique that enables direct inversion of 3D phase and absorption from intensity-only measurements for weakly scattering samples. We derive a novel linear forward model,…
Increasing interest in three-dimensional nanostructures adds impetus to electron microscopy techniques capable of imaging at or below the nanoscale in three dimensions. We present a reconstruction algorithm that takes as input a focal…
Due to limited size and imperfect of the optical components in a spectrometer, aberration has inevitably been brought into two-dimensional multi-fiber spectrum image in LAMOST, which leads to obvious spacial variation of the point spread…
Current Point-based detectors can only learn from the provided points, with limited receptive fields and insufficient global learning capabilities for such targets. In this paper, we present a novel Point Dilation Mechanism for single-stage…
As the perception range of LiDAR increases, LiDAR-based 3D object detection becomes a dominant task in the long-range perception task of autonomous driving. The mainstream 3D object detectors usually build dense feature maps in the network…
Spike cameras, as an innovative neuromorphic camera that captures scenes with the 0-1 bit stream at 40 kHz, are increasingly employed for the 3D reconstruction task via Neural Radiance Fields (NeRF) or 3D Gaussian Splatting (3DGS). Previous…
Using the 1-BM-C beamline at the Advanced Photon Source (APS), we have performed the initial indirect x-ray imaging point-spread-function (PSF) test of a unique 88-mm diameter YAG:Ce single crystal of only 100-micron thickness. The crystal…
Fluorescence microscopy is essential in biological and medical research, providing critical insights into cellular structures. However, limited by optical diffraction and background noise, a substantial amount of hidden information is still…
We propose a method for optical nano-imaging in which the structure of a three-dimensional inhomogeneous medium may be recovered from far-field power measurements. Neither phase control of the illuminating field nor phase measurements of…