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The aggressiveness of prostate cancer, the most common cancer in men worldwide, is primarily assessed based on histopathological data using the Gleason scoring system. While artificial intelligence (AI) has shown promise in accurately…

Graph Neural Networks have been widely applied in critical decision-making areas that demand interpretable predictions, leading to the flourishing development of interpretability algorithms. However, current graph interpretability…

Machine Learning · Computer Science 2024-09-04 Xiaodi Li , Jianfeng Gui , Qian Gao , Haoyuan Shi , Zhenyu Yue

Society's capacity for algorithmic problem-solving has never been greater. Artificial Intelligence is now applied across more domains than ever, a consequence of powerful abstractions, abundant data, and accessible software. As capabilities…

Machine Learning · Statistics 2024-08-20 Kris Sankaran

It is imperative that breast cancer is detected precisely and timely to improve patient outcomes. Diagnostic methodologies have traditionally relied on unimodal approaches; however, medical data analytics is integrating diverse data sources…

Machine Learning · Computer Science 2024-06-21 Faseela Abdullakutty , Younes Akbari , Somaya Al-Maadeed , Ahmed Bouridane , Rifat Hamoudi

This paper proposes an alternative approach to the basic taxonomy of explanations produced by explainable artificial intelligence techniques. Methods of Explainable Artificial Intelligence (XAI) were developed to answer the question why a…

Artificial Intelligence · Computer Science 2023-01-31 Sven Nomm

Concept-based explanation methods aim at making machine learning models more transparent by finding the most important semantic features of an input (e.g., colors, patterns, shapes) for a given prediction task. However, these methods…

Machine Learning · Computer Science 2025-10-02 Jacopo Teneggi , Zhenzhen Wang , Paul H. Yi , Tianmin Shu , Jeremias Sulam

The popularity of machine learning has increased the risk of unfair models getting deployed in high-stake applications, such as justice system, drug/vaccination design, and medical diagnosis. Although there are effective methods to train…

Machine Learning · Computer Science 2022-07-14 Mohit Bajaj , Lingyang Chu , Vittorio Romaniello , Gursimran Singh , Jian Pei , Zirui Zhou , Lanjun Wang , Yong Zhang

The increasing incorporation of Artificial Intelligence in the form of automated systems into decision-making procedures highlights not only the importance of decision theory for automated systems but also the need for these decision…

Artificial Intelligence · Computer Science 2018-08-23 Tarek R. Besold , Sara L. Uckelman

Everyday life is increasingly influenced by artificial intelligence, and there is no question that machine learning algorithms must be designed to be reliable and trustworthy for everyone. Specifically, computer scientists consider an…

Machine Learning · Computer Science 2025-10-29 Sara Narteni , Alberto Carlevaro , Fabrizio Dabbene , Marco Muselli , Maurizio Mongelli

We propose a nonparametric additive model for estimating interpretable value functions in reinforcement learning, with an application in optimizing postoperative recovery through personalized, adaptive recommendations. While reinforcement…

Machine Learning · Statistics 2025-06-02 Patrick Emedom-Nnamdi , Timothy R. Smith , Jukka-Pekka Onnela , Junwei Lu

Machine learning models that offer excellent predictive performance often lack the interpretability necessary to support integrated human machine decision-making. In clinical medicine and other high-risk settings, domain experts may be…

Machine Learning · Computer Science 2021-04-19 Zach Wood-Doughty , Isabel Cachola , Mark Dredze

Understanding why machine learning models behave the way they do empowers both system designers and end-users in many ways: in model selection, feature engineering, in order to trust and act upon the predictions, and in more intuitive user…

Machine Learning · Statistics 2016-06-20 Marco Tulio Ribeiro , Sameer Singh , Carlos Guestrin

As artificial intelligence becomes increasingly pervasive and powerful, the ability to audit AI-based systems is growing in importance. However, explainability for artificial intelligence systems is not a one-size-fits-all solution;…

Human-Computer Interaction · Computer Science 2025-10-13 Nicola Rossberg , Bennett Kleinberg , Barry O'Sullivan , Luca Longo , Andrea Visentin

Explainable information retrieval is an emerging research area aiming to make transparent and trustworthy information retrieval systems. Given the increasing use of complex machine learning models in search systems, explainability is…

Information Retrieval · Computer Science 2022-11-07 Avishek Anand , Lijun Lyu , Maximilian Idahl , Yumeng Wang , Jonas Wallat , Zijian Zhang

Interpretability of machine learning models is critical for data-driven precision medicine efforts. However, highly predictive models are generally complex and are difficult to interpret. Here using Model-Agnostic Explanations algorithm, we…

Quantitative Methods · Quantitative Biology 2016-10-31 Gajendra Jung Katuwal , Robert Chen

Individualized treatment rules (ITRs) for treatment recommendation is an important topic for precision medicine as not all beneficial treatments work well for all individuals. Interpretability is a desirable property of ITRs, as it helps…

Methodology · Statistics 2023-11-06 Jacob M. Maronge , Jared D. Huling , Guanhua Chen

Artificial intelligence (AI) provides considerable opportunities to assist human work. However, one crucial challenge of human-AI collaboration is that many AI algorithms operate in a black-box manner where the way how the AI makes…

Human-Computer Interaction · Computer Science 2024-06-13 Julian Senoner , Simon Schallmoser , Bernhard Kratzwald , Stefan Feuerriegel , Torbjørn Netland

Objective: To combine medical knowledge and medical data to interpretably predict the risk of disease. Methods: We formulated the disease prediction task as a random walk along a knowledge graph (KG). Specifically, we build a KG to record…

Machine Learning · Computer Science 2023-01-09 Zhoujian Sun , Wei Dong , Jinlong Shi , Zhengxing Huang

Feature selection of high-dimensional labeled data with limited observations is critical for making powerful predictive modeling accessible, scalable, and interpretable for domain experts. Spectroscopy data, which records the interaction…

Machine Learning · Computer Science 2022-02-10 Frantishek Akulich , Hadis Anahideh , Manaf Sheyyab , Dhananjay Ambre

Breast cancer (BC) stands as one of the most common malignancies affecting women worldwide, necessitating advancements in diagnostic methodologies for better clinical outcomes. This article provides a comprehensive exploration of the…

Artificial Intelligence · Computer Science 2025-12-11 Samita Bai , Sidra Nasir , Rizwan Ahmed Khan , Alexandre Meyer , Hubert Konik