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As predictive machine learning models become increasingly adopted and advanced, their role has evolved from merely predicting outcomes to actively shaping them. This evolution has underscored the importance of Trustworthy AI, highlighting…

Machine Learning · Computer Science 2025-03-07 Fabio Michele Russo , Carlo Metta , Anna Monreale , Salvatore Rinzivillo , Fabio Pinelli

This paper claims that machine learning models deployed in high stakes domains such as medicine must be interpretable, shareable, reproducible and accountable. We argue that these principles should form the foundational design criteria for…

Machine Learning · Computer Science 2025-08-25 Ayyüce Begüm Bektaş , Mithat Gönen

Given the sheer volume of surgical procedures and the significant rate of postoperative fatalities, assessing and managing surgical complications has become a critical public health concern. Existing artificial intelligence (AI) tools for…

Development of interpretable machine learning models for clinical healthcare applications has the potential of changing the way we understand, treat, and ultimately cure, diseases and disorders in many areas of medicine. These models can…

Machine Learning · Computer Science 2019-08-06 Qingzhu Gao , Humberto Gonzalez , Parvez Ahammad

Interpretability provides a means for humans to verify aspects of machine learning (ML) models and empower human+ML teaming in situations where the task cannot be fully automated. Different contexts require explanations with different…

Machine Learning · Computer Science 2024-07-15 Zixi Chen , Varshini Subhash , Marton Havasi , Weiwei Pan , Finale Doshi-Velez

Explanations in a recommender system assist users in making informed decisions among a set of recommended items. Great research attention has been devoted to generating natural language explanations to depict how the recommendations are…

Information Retrieval · Computer Science 2022-02-22 Peng Wang , Renqin Cai , Hongning Wang

In recent years, Artificial Intelligence technology has excelled in various applications across all domains and fields. However, the various algorithms in neural networks make it difficult to understand the reasons behind decisions. For…

Artificial Intelligence · Computer Science 2025-05-13 Bowen Long , Enjie Liu , Renxi Qiu , Yanqing Duan

Systematic literature reviews are the highest quality of evidence in research. However, the review process is hindered by significant resource and data constraints. The Literature Review Network (LRN) is the first of its kind explainable AI…

Digital Libraries · Computer Science 2024-08-13 Joshua Morriss , Tod Brindle , Jessica Bah Rösman , Daniel Reibsamen , Andreas Enz

In the context of human-in-the-loop Machine Learning applications, like Decision Support Systems, interpretability approaches should provide actionable insights without making the users wait. In this paper, we propose Accelerated…

Machine Learning · Computer Science 2021-12-24 David Dandolo , Chiara Masiero , Mattia Carletti , Davide Dalle Pezze , Gian Antonio Susto

Deep neural networks for medical image diagnosis often achieve high predictive accuracy while relying on spurious or clinically irrelevant visual cues, limiting their trustworthiness in practice. Post-hoc explanation methods are widely used…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Zubair Faruqui , Rahul Dubey

Recent works in Explainable AI mostly address the transparency issue of black-box models or create explanations for any kind of models (i.e., they are model-agnostic), while leaving explanations of interpretable models largely…

Artificial Intelligence · Computer Science 2022-05-24 Piyawat Lertvittayakumjorn , Francesca Toni

Accurate and interpretable prediction of estimated glomerular filtration rate (eGFR) is essential for managing chronic kidney disease (CKD) and supporting clinical decisions. Recent advances in Large Multimodal Models (LMMs) have shown…

Machine Learning · Computer Science 2025-07-31 Peng-Yi Wu , Pei-Cing Huang , Ting-Yu Chen , Chantung Ku , Ming-Yen Lin , Yihuang Kang

Artificial intelligence (AI) systems utilizing deep neural networks (DNNs) and machine learning (ML) algorithms are widely used for solving important problems in bioinformatics, biomedical informatics, and precision medicine. However,…

Quantitative Methods · Quantitative Biology 2023-02-24 Md. Rezaul Karim , Tanhim Islam , Oya Beyan , Christoph Lange , Michael Cochez , Dietrich Rebholz-Schuhmann , Stefan Decker

We emphasize the importance of asking the right question when interpreting the decisions of a learning model. We discuss a natural extension of the theoretical machinery from Janzing et. al. 2020, which answers the question "Why did my…

Machine Learning · Statistics 2020-12-11 Debraj Basu

In recent years, Artificial Intelligence (AI) algorithms have been proven to outperform traditional statistical methods in terms of predictivity, especially when a large amount of data was available. Nevertheless, the "black box" nature of…

Machine Learning · Statistics 2021-10-14 Nicola Picchiotti , Marco Gori

Artificial intelligence supports healthcare professionals with predictive modeling, greatly transforming clinical decision-making. This study addresses the crucial need for fairness and explainability in AI applications within healthcare to…

Machine Learning · Computer Science 2024-11-27 Chia-Hsuan Chang , Xiaoyang Wang , Christopher C. Yang

Verification of biomedical claims is critical for healthcare decision-making, public health policy and scientific research. We present an interactive biomedical claim verification system by integrating LLMs, transparent model explanations,…

Human-Computer Interaction · Computer Science 2025-03-03 Siting Liang , Daniel Sonntag

Interpretability is essential for machine learning algorithms in high-stakes application fields such as medical image analysis. However, high-performing black-box neural networks do not provide explanations for their predictions, which can…

Computer Vision and Pattern Recognition · Computer Science 2023-08-09 Susu Sun , Stefano Woerner , Andreas Maier , Lisa M. Koch , Christian F. Baumgartner

Automated machine learning (AutoML) systems aim to enable training machine learning (ML) models for non-ML experts. A shortcoming of these systems is that when they fail to produce a model with high accuracy, the user has no path to improve…

Machine Learning · Computer Science 2021-02-23 Behnaz Arzani , Kevin Hsieh , Haoxian Chen

The currently dominating artificial intelligence and machine learning technology, neural networks, builds on inductive statistical learning. Neural networks of today are information processing systems void of understanding and reasoning…

Artificial Intelligence · Computer Science 2022-08-26 Lars Holmberg
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