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Current clinical decision support systems (CDSSs) typically base their predictions on correlation, not causation. In recent years, causal machine learning (ML) has emerged as a promising way to improve decision-making with CDSSs by offering…

Human-Computer Interaction · Computer Science 2026-04-17 Domenique Zipperling , Lukas Schmidt , Benedikt Hahn , Niklas Kühl , Steven Kimbrough

The emergence of vision-language models (VLMs) has opened new possibilities for clinical reasoning and has shown promising performance in dermatological diagnosis. However, their trustworthiness and clinical utility are often limited by…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Zehao Liu , Wejieying Ren , Jipeng Zhang , Tianxiang Zhao , Jingxi Zhu , Xiaoting Li , Vasant G. Honavar

Vision-Language Models (VLMs) have been increasingly applied in real-world scenarios due to their outstanding understanding and reasoning capabilities. Although VLMs have already demonstrated impressive capabilities in common visual…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Yuechen Xie , Xiaoyan Zhang , Yicheng Shan , Hao Zhu , Rui Tang , Rong Wei , Mingli Song , Yuanyu Wan , Jie Song

Artificial intelligence-augmented technology represents a considerable opportunity for improving healthcare delivery. Significant progress has been made to demonstrate the value of complex models to enhance clinicians` efficiency in…

Human-Computer Interaction · Computer Science 2025-04-08 Mohammad Golam Kibria , Lauren Kucirka , Javed Mostafa

Integrating large language models (LLMs) like DeepSeek R1 into healthcare requires rigorous evaluation of their reasoning alignment with clinical expertise. This study assesses DeepSeek R1's medical reasoning against expert patterns using…

Computation and Language · Computer Science 2025-04-02 Birger Moell , Fredrik Sand Aronsson , Sanian Akbar

A chief goal of artificial intelligence is to build machines that think like people. Yet it has been argued that deep neural network architectures fail to accomplish this. Researchers have asserted these models' limitations in the domains…

Machine Learning · Computer Science 2024-08-09 Luca M. Schulze Buschoff , Elif Akata , Matthias Bethge , Eric Schulz

The rise of large language models (LLMs) has transformed healthcare by offering clinical guidance, yet their direct deployment to patients poses safety risks due to limited domain expertise. To mitigate this, we propose repositioning LLMs…

Computation and Language · Computer Science 2025-10-14 Wenya Xie , Qingying Xiao , Yu Zheng , Xidong Wang , Junying Chen , Ke Ji , Anningzhe Gao , Prayag Tiwari , Xiang Wan , Feng Jiang , Benyou Wang

Vision-language models (VLMs) often produce chain-of-thought (CoT) explanations that sound plausible yet fail to reflect the underlying decision process, undermining trust in high-stakes clinical use. Existing evaluations rarely catch this…

Vision evaluations are typically done through multi-step processes. In most contemporary fields, experts analyze images using structured, evidence-based adaptive questioning. In plant pathology, botanists inspect leaf images, identify…

Computer Vision and Pattern Recognition · Computer Science 2026-04-24 Syed Nazmus Sakib , Nafiul Haque , Shahrear Bin Amin , Hasan Muhammad Abdullah , Md. Mehedi Hasan , Mohammad Zabed Hossain , Shifat E. Arman

While large language models are capable diagnostic tools, the impact of multi-agent topology on diagnostic accuracy remains underexplored. This study evaluates four agent topologies, Control (single agent), Hierarchical, Adversarial, and…

Multiagent Systems · Computer Science 2026-03-10 Ahmed Almasoud

This paper presents an innovative large language model (LLM) agent framework for enhancing diagnostic accuracy in simulated clinical environments using the AgentClinic benchmark. The proposed automatic correction enables doctor agents to…

Artificial Intelligence · Computer Science 2024-10-15 Abhishek Dutta , Yen-Che Hsiao

Artificial intelligence (AI) holds great promise for supporting clinical trials, from patient recruitment and endpoint assessment to treatment response prediction. However, deploying AI without safeguards poses significant risks,…

Machine Learning · Computer Science 2025-10-09 Yao Chen , David Ohlssen , Aimee Readie , Gregory Ligozio , Ruvie Martin , Thibaud Coroller

Clinical document classification is essential for converting unstructured medical texts into standardised ICD-10 diagnoses, yet it faces challenges due to complex medical language, privacy constraints, and limited annotated datasets. Large…

Computation and Language · Computer Science 2026-02-03 Akram Mustafa , Usman Naseem , Mostafa Rahimi Azghadi

Medical visual question answering (Med-VQA) is a machine learning task that aims to create a system that can answer natural language questions based on given medical images. Although there has been rapid progress on the general VQA task,…

Computer Vision and Pattern Recognition · Computer Science 2023-09-21 Louisa Canepa , Sonit Singh , Arcot Sowmya

Medical foundation models have shown promise in controlled benchmarks, yet widespread deployment remains hindered by reliance on task-specific fine-tuning. Here, we introduce DermFM-Zero, a dermatology vision-language foundation model…

Artificial Intelligence (AI) repeatedly match or outperform radiologists in lab experiments. However, real-world implementations of radiological AI-based systems are found to provide little to no clinical value. This paper explores how to…

Visual reasoning is a core component of human intelligence and a critical capability for advanced multimodal models. Yet current reasoning evaluations of multimodal large language models (MLLMs) often rely on text descriptions and allow…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Weiye Xu , Jiahao Wang , Weiyun Wang , Zhe Chen , Wengang Zhou , Aijun Yang , Lewei Lu , Houqiang Li , Xiaohua Wang , Xizhou Zhu , Wenhai Wang , Jifeng Dai , Jinguo Zhu

Recent technological advances in healthcare have led to unprecedented growth in patient data quantity and diversity. While artificial intelligence (AI) models have shown promising results in analyzing individual data modalities, there is…

Artificial Intelligence · Computer Science 2024-11-07 Daan Schouten , Giulia Nicoletti , Bas Dille , Catherine Chia , Pierpaolo Vendittelli , Megan Schuurmans , Geert Litjens , Nadieh Khalili

Dermatological conditions affect 1.9 billion people globally, yet accurate diagnosis remains challenging due to limited specialist availability and complex clinical presentations. Family history significantly influences skin disease…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Satya Narayana Panda , Vaishnavi Kukkala , Spandana Iyer

Artificial intelligence (AI) continues to transform data analysis in many domains. Progress in each domain is driven by a growing body of annotated data, increased computational resources, and technological innovations. In medicine, the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-09 Ahmad Chaddad , Qizong lu , Jiali Li , Yousef Katib , Reem Kateb , Camel Tanougast , Ahmed Bouridane , Ahmed Abdulkadir