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We study the problem of learning to choose from m discrete treatment options (e.g., news item or medical drug) the one with best causal effect for a particular instance (e.g., user or patient) where the training data consists of passive…

Machine Learning · Statistics 2017-08-02 Nathan Kallus

Motivation: Drug combination is a sensible strategy for disease treatment by improving the efficacy and reducing concomitant side effects. Due to the large number of possible combinations among candidate compounds, exhaustive screening is…

Quantitative Methods · Quantitative Biology 2020-02-26 Liang Yu , Mingfei Xia , Lin Gao

The concept of personalised medicine in cancer therapy is becoming increasingly important. There already exist drugs administered specifically for patients with tumours presenting well-defined mutations. However, the field is still in its…

Biomolecules · Quantitative Biology 2024-08-26 Abbi Abdel-Rehim , Oghenejokpeme Orhobor , Gareth Griffiths , Larisa Soldatova , Ross D. King

Time series modeling is crucial for many applications, however, it faces challenges such as complex spatio-temporal dependencies and distribution shifts in learning from historical context to predict task-specific outcomes. To address these…

Artificial Intelligence · Computer Science 2024-08-28 Chidaksh Ravuru , Sagar Srinivas Sakhinana , Venkataramana Runkana

In recent years, many studies extract aspects from user reviews and integrate them with ratings for improving the recommendation performance. The common aspects mentioned in a user's reviews and a product's reviews indicate indirect…

Information Retrieval · Computer Science 2019-04-18 Xinyu Guan , Zhiyong Cheng , Xiangnan He , Yongfeng Zhang , Zhibo Zhu , Qinke Peng , Tat-Seng Chua

Federated Learning (FL) allows the training of deep neural networks in a distributed and privacy-preserving manner. However, this concept suffers from malfunctioning updates sent by the attending clients that cause global model performance…

Machine Learning · Computer Science 2025-08-05 Mirko Konstantin , Moritz Fuchs , Anirban Mukhopadhyay

Personalized medicine has become an important part of medicine, for instance predicting individual drug responses based on genomic information. However, many current statistical methods are not tailored to this task, because they overlook…

Applications · Statistics 2019-10-03 Shih-Ting Huang , Yannick Düren , Kristoffer H. Hellton , Johannes Lederer

In the past decade, with the development of big data technology, an increasing amount of patient information has been stored as electronic health records (EHRs). Leveraging these data, various doctor recommendation systems have been…

Information Retrieval · Computer Science 2022-07-14 Luning Bi , Yunlong Wang , Fan Zhang , Zhuqing Liu , Yong Cai , Emily Zhao

Individualized treatment rules (ITRs) for treatment recommendation is an important topic for precision medicine as not all beneficial treatments work well for all individuals. Interpretability is a desirable property of ITRs, as it helps…

Methodology · Statistics 2023-11-06 Jacob M. Maronge , Jared D. Huling , Guanhua Chen

Recommender Systems are an integral part of music sharing platforms. Often the aim of these systems is to increase the time, the user spends on the platform and hence having a high commercial value. The systems which aim at increasing the…

Information Retrieval · Computer Science 2018-11-21 Noveen Sachdeva , Kartik Gupta , Vikram Pudi

Large Language Models (LLMs) have shown promising performance on diverse medical benchmarks, highlighting their potential in supporting real-world clinical tasks. Retrieval-Augmented Generation (RAG) has emerged as a key approach for…

Computation and Language · Computer Science 2025-09-30 Kaishuai Xu , Wenjun Hou , Yi Cheng , Wenjie Li

In recent decades, traditional drug research and development have been facing challenges such as high cost, long timelines, and high risks. To address these issues, many computational approaches have been suggested for predicting the…

Quantitative Methods · Quantitative Biology 2023-09-13 Chunyan Ao , Zhichao Xiao , Lixin Guan , Liang Yu

Healthcare and medicine are multimodal disciplines that deal with multimodal data for reasoning and diagnosing multiple diseases. Although some multimodal reasoning models have emerged for reasoning complex tasks in scientific domains,…

Artificial Intelligence · Computer Science 2025-09-16 Susanta Mitra

Interfractional geometric uncertainties can lead to deviations of the actual delivered dose from the prescribed dose distribution. To better handle these uncertainties during treatment, the authors propose a dynamic framework for robust…

Medical Physics · Physics 2019-05-16 Michelle Böck , Kjell Eriksson , Anders Forsgren

Evidence suggests that medication adherence applications (apps) are one of the most effective methods to remind patients to take medication on time. Reminders via apps are overwhelming today, consumers discard using them after a brief…

Human-Computer Interaction · Computer Science 2023-10-24 Nawal Chanane , Farhaan Mirza , M. Asif Naeem

Interactive conversational recommender systems have gained significant attention for their ability to capture user preferences through natural language interactions. However, existing approaches face substantial challenges in handling…

Artificial Intelligence · Computer Science 2025-10-03 Bo Ma , Hang Li , ZeHua Hu , XiaoFan Gui , LuYao Liu , Simon Lau

Machine Learning's proliferation in critical fields such as healthcare, banking, and criminal justice has motivated the creation of tools which ensure trust and transparency in ML models. One such tool is Actionable Recourse (AR) for…

Machine Learning · Computer Science 2023-09-07 Jayanth Yetukuri , Ian Hardy , Yang Liu

Medication recommendation targets to provide a proper set of medicines according to patients' diagnoses, which is a critical task in clinics. Currently, the recommendation is manually conducted by doctors. However, for complicated cases,…

Machine Learning · Computer Science 2022-02-21 Rui Wu , Zhaopeng Qiu , Jiacheng Jiang , Guilin Qi , Xian Wu

While large reasoning models demonstrate strong performance on complex tasks, they lack the ability to adjust reasoning token usage based on task difficulty. This often leads to the "overthinking" problem -- excessive and unnecessary…

Computation and Language · Computer Science 2025-10-14 Siye Wu , Jian Xie , Yikai Zhang , Aili Chen , Kai Zhang , Yu Su , Yanghua Xiao

We describe and study a model for an Automated Online Recommendation System (AORS) in which a user's preferences can be time-dependent and can also depend on the history of past recommendations and play-outs. The three key features of the…

Machine Learning · Computer Science 2016-03-31 Rahul Meshram , Aditya Gopalan , D. Manjunath