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In the treatment of complex diseases, treatment regimens using a single drug often yield limited efficacy and can lead to drug resistance. In contrast, combination drug therapies can significantly improve therapeutic outcomes through…

Machine Learning · Computer Science 2026-04-24 Jiyan Song , Wenyang Wang , Chengcheng Yan , Zhiquan Han , Feifei Zhao

Recent years have witnessed the rapid accumulation of massive electronic medical records (EMRs), which highly support the intelligent medical services such as drug recommendation. However, prior arts mainly follow the traditional…

Information Retrieval · Computer Science 2021-02-09 Zhi Zheng , Chao Wang , Tong Xu , Dazhong Shen , Penggang Qin , Baoxing Huai , Tongzhu Liu , Enhong Chen

Accurate prediction of disease trajectories is critical for early identification and timely treatment of patients at risk. Conventional methods in survival analysis are often constrained by strong parametric assumptions and limited in their…

Machine Learning · Computer Science 2018-11-28 Daniel Jarrett , Jinsung Yoon , Mihaela van der Schaar

Appropriate dosing of radiation is crucial to patient safety in radiotherapy. Current quality assurance depends heavily on a peer-review process, where the physicians' peer review on each patient's treatment plan, including dose and…

Machine Learning · Computer Science 2021-12-01 Qiongge Li , Jean Wright , Russell Hales , Ranh Voong , Todd McNutt

One primary goal of precision medicine is to estimate the individualized treatment rules (ITRs) that optimize patients' health outcomes based on individual characteristics. Health studies with multiple treatments are commonly seen in…

Methodology · Statistics 2025-05-07 Xuqiao Li , Qiuyan Zhou , Ying Wu , Ying Yan

With the increasing amounts of high-dimensional heterogeneous data to be processed, multi-modality feature selection has become an important research direction in medical image analysis. Traditional methods usually depict the data structure…

Computer Vision and Pattern Recognition · Computer Science 2022-04-11 Yuang Shi , Chen Zu , Mei Hong , Luping Zhou , Lei Wang , Xi Wu , Jiliu Zhou , Daoqiang Zhang , Yan Wang

In modern biomedical and econometric studies, longitudinal processes are often characterized by complex time-varying associations and abrupt regime shifts that are shared across correlated outcomes. Standard functional data analysis (FDA)…

Methodology · Statistics 2026-01-28 Baolin Chen , Mengfei Ran

Mental health assessment is crucial for early intervention and effective treatment, yet traditional clinician-based approaches are limited by the shortage of qualified professionals. Recent advances in artificial intelligence have sparked…

Computation and Language · Computer Science 2025-08-18 Jinpeng Hu , Ao Wang , Qianqian Xie , Hui Ma , Zhuo Li , Dan Guo

Time series forecasting plays a pivotal role in critical domains such as energy management and financial markets. Although deep learning-based approaches (e.g., MLP, RNN, Transformer) have achieved remarkable progress, the prevailing…

Machine Learning · Computer Science 2025-10-24 Renzhao Liang , Sizhe Xu , Chenggang Xie , Jingru Chen , Feiyang Ren , Shu Yang , Takahiro Yabe

Recommendation is crucial in both academia and industry, and various techniques are proposed such as content-based collaborative filtering, matrix factorization, logistic regression, factorization machines, neural networks and multi-armed…

Information Retrieval · Computer Science 2019-10-30 Feng Liu , Ruiming Tang , Xutao Li , Weinan Zhang , Yunming Ye , Haokun Chen , Huifeng Guo , Yuzhou Zhang

Conventional recommendation systems (RSs) are typically optimized to enhance performance metrics uniformly across all training samples. This makes it hard for data-driven RSs to cater to a diverse set of users due to the varying properties…

Information Retrieval · Computer Science 2024-05-03 Kirandeep Kaur , Chirag Shah

The research explores the utilization of a deep learning model employing an attention mechanism in medical text mining. It targets the challenge of analyzing unstructured text information within medical data. This research seeks to enhance…

Computation and Language · Computer Science 2024-06-04 Lingxi Xiao , Muqing Li , Yinqiu Feng , Meiqi Wang , Ziyi Zhu , Zexi Chen

The application of Large Language Models (LLMs) in recommender systems faces key challenges in delivering deep personalization and intelligent reasoning, especially for interactive scenarios. Current methods are often constrained by limited…

Information Retrieval · Computer Science 2025-10-17 Jiani Huang , Xingchen Zou , Lianghao Xia , Qing Li

Patient similarity assessment, which identifies patients similar to a given patient, can help improve medical care. The assessment can be performed using Electronic Medical Records (EMRs). Patient similarity measurement requires converting…

Information Retrieval · Computer Science 2022-09-20 Hoda Memarzadeh , Nasser Ghadiri , Matthias Samwald , Maryam Lotfi Shahreza

Large language models (LLMs) holds significant promise in achieving general medication recommendation systems owing to their comprehensive interpretation of clinical notes and flexibility to medication encoding. We evaluated both…

Information Retrieval · Computer Science 2025-08-05 Zihao Zhao , Chenxiao Fan , Junlong Liu , Zheng Wang , Xiangnan He , Chongming Gao , Juan Li , Fuli Feng

Query optimization is a crucial component for the efficacy of Retrieval-Augmented Generation (RAG) systems. While reinforcement learning (RL)-based agentic and reasoning methods have recently emerged as a promising direction on query…

Artificial Intelligence · Computer Science 2026-01-30 Wei Wen , Sihang Deng , Tianjun Wei , Keyu Chen , Ruizhi Qiao , Xing Sun

Large Reasoning Language Models (LRLMs or LRMs) demonstrate remarkable capabilities in complex reasoning tasks, but suffer from significant computational inefficiencies due to overthinking phenomena. Existing efficient reasoning methods…

Artificial Intelligence · Computer Science 2025-10-13 Dongqi Zheng

The explosion of multimedia data in information-rich environments has intensified the challenges of personalized content discovery, positioning recommendation systems as an essential form of passive data management. Multimodal sequential…

Information Retrieval · Computer Science 2026-03-05 Jinfeng Xu , Zheyu Chen , Shuo Yang , Jinze Li , Hewei Wang , Yijie Li , Jianheng Tang , Yunhuai Liu , Edith C. H. Ngai

Recommendation systems aim to assist users to discover most preferred contents from an ever-growing corpus of items. Although recommenders have been greatly improved by deep learning, they still faces several challenges: (1) Behaviors are…

Information Retrieval · Computer Science 2020-11-19 Wendi Ji , Keqiang Wang , Xiaoling Wang , TingWei Chen , Alexandra Cristea

This replication study modifies ALMM, the Adaptive Linear Mapping Model constructed for the next song recommendation, to the news recommendation problem on the MIND dataset. The original version of ALMM computes latent representations for…

Information Retrieval · Computer Science 2025-08-05 Omar Elgohary , Nathan Jorgenson , Trenton Marple
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