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Recent advances in AI for science have highlighted the power of contrastive learning in bridging heterogeneous biological data modalities. Building on this paradigm, we propose HIPPO (HIerarchical Protein-Protein interaction prediction…

Machine Learning · Computer Science 2025-08-05 Shiyi Liu , Buwen Liang , Yuetong Fang , Zixuan Jiang , Renjing Xu

AI-assisted molecular optimization is a very active research field as it is expected to provide the next-generation drugs and molecular materials. An important difficulty is that the properties to be optimized rely on costly evaluations.…

Machine Learning · Computer Science 2025-05-19 Jules Leguy , Thomas Cauchy , Beatrice Duval , Benoit Da Mota

Selecting the right set of hyperparameters is crucial in time series forecasting. The classical temporal cross-validation framework for hyperparameter optimization (HPO) often leads to poor test performance because of a possible mismatch…

Physical Human-Robot Interaction (pHRI) is critical for implementing Industry 5.0, which focuses on human-centric approaches. However, few studies explore the practical alignment of pHRI to industrial-grade performance. This paper…

Robotics · Computer Science 2025-05-19 Bastien Muraccioli , Mathieu Celerier , Mehdi Benallegue , Gentiane Venture

In swarm robotics, confrontation including the pursuit-evasion game is a key scenario. High uncertainty caused by unknown opponents' strategies, dynamic obstacles, and insufficient training complicates the action space into a hybrid…

Robotics · Computer Science 2024-10-28 Qizhen Wu , Kexin Liu , Lei Chen , Jinhu Lü

The integration of collaborative robots into industrial environments has improved productivity, but has also highlighted significant challenges related to operator safety and ergonomics. This paper proposes an innovative framework that…

Robotics · Computer Science 2025-04-15 Francesco Iodice , Elena De Momi , Arash Ajoudani

Optimization techniques are frequently applied in science and engineering research and development. Evolutionary algorithms, as a kind of general-purpose metaheuristic, have been shown to be very effective in solving a wide range of…

Neural and Evolutionary Computing · Computer Science 2015-02-03 James J. Q. Yu , Victor O. K. Li , Albert Y. S. Lam

The value-loading problem is a significant challenge for researchers aiming to create artificial intelligence (AI) systems that align with human values and preferences. This problem requires a method to define and regulate safe and optimal…

Artificial Intelligence · Computer Science 2026-03-02 Nathan I. N. Henry , Mangor Pedersen , Matt Williams , Jamin L. B. Martin , Liesje Donkin

Robotics and automation offer massive accelerations for solving intractable, multivariate scientific problems such as materials discovery, but the available search spaces can be dauntingly large. Bayesian optimization (BO) has emerged as a…

Machine Learning · Computer Science 2025-09-22 Abdoulatif Cisse , Xenophon Evangelopoulos , Sam Carruthers , Vladimir V. Gusev , Andrew I. Cooper

This paper proposes a two-level hierarchical matching framework for Integrated Hybrid Resources (IHRs) with grid constraints. An IHR is a collection of Renewable Energy Sources (RES) and flexible customers within a certain power system…

Systems and Control · Electrical Eng. & Systems 2023-09-21 Majid Majidi , Deepan Muthirayan , Masood Parvania , Pramod P. Khargonekar

Adversarial training (AT) is widely considered the state-of-the-art technique for improving the robustness of deep neural networks (DNNs) against adversarial examples (AE). Nevertheless, recent studies have revealed that adversarially…

Machine Learning · Computer Science 2023-08-04 Chenhao Lin , Xiang Ji , Yulong Yang , Qian Li , Chao Shen , Run Wang , Liming Fang

The hyper-parameter optimization (HPO) process is imperative for finding the best-performing Convolutional Neural Networks (CNNs). The automation process of HPO is characterized by its sizable computational footprint and its lack of…

Machine Learning · Computer Science 2024-05-03 Ibrahim Shaer , Soodeh Nikan , Abdallah Shami

Modern industrial systems require updated approaches to safety management, as the tight interplay between cyber-physical, human, and organizational factors has driven their processes toward increasing complexity. In addition to dealing with…

Systems and Control · Electrical Eng. & Systems 2025-09-09 Francesco Simone , Marco Bortolini , Giovanni Mazzuto , Giulio di Gravio , Riccardo Patriarca

This paper addresses the challenges of predicting bioprocess performance, particularly in monoclonal antibody (mAb) production, where conventional statistical methods often fall short due to time-series data's complexity and high…

Machine Learning · Computer Science 2024-11-05 Ali Nik-Khorasani , Thanh Tung Khuat , Bogdan Gabrys

Hierarchical reinforcement learning is a promising approach to tackle long-horizon decision-making problems with sparse rewards. Unfortunately, most methods still decouple the lower-level skill acquisition process and the training of a…

Machine Learning · Computer Science 2020-05-15 Alexander C. Li , Carlos Florensa , Ignasi Clavera , Pieter Abbeel

Differentiable reinforcement learning (RL) frameworks like DiffRO offer a powerful approach for controllable text-to-speech (TTS), but are vulnerable to reward hacking, particularly for nuanced tasks like emotion control. The policy model…

Sound · Computer Science 2026-02-17 Cong Wang , Changfeng Gao , Yang Xiang , Zhihao Du , Keyu An , Han Zhao , Qian Chen , Xiangang Li , Yingming Gao , Ya Li

Recently, malevolent user hacking has become a huge problem for real-world companies. In order to learn predictive models for recommender systems, factorization techniques have been developed to deal with user-item ratings. In this paper,…

Information Retrieval · Computer Science 2022-11-08 Li Wang , Qiang Zhao , Wei Wang

We study how to effectively leverage expert feedback to learn sequential decision-making policies. We focus on problems with sparse rewards and long time horizons, which typically pose significant challenges in reinforcement learning. We…

Machine Learning · Computer Science 2018-06-12 Hoang M. Le , Nan Jiang , Alekh Agarwal , Miroslav Dudík , Yisong Yue , Hal Daumé

Recent advancements in reinforcement learning have made significant impacts across various domains, yet they often struggle in complex multi-agent environments due to issues like algorithm instability, low sampling efficiency, and the…

Multiagent Systems · Computer Science 2024-08-22 Cheng Xu , Changtian Zhang , Yuchen Shi , Ran Wang , Shihong Duan , Yadong Wan , Xiaotong Zhang

Portfolio management via reinforcement learning is at the forefront of fintech research, which explores how to optimally reallocate a fund into different financial assets over the long term by trial-and-error. Existing methods are…

Artificial Intelligence · Computer Science 2021-02-09 Rundong Wang , Hongxin Wei , Bo An , Zhouyan Feng , Jun Yao