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The analysis of fundus images is critical for the early detection and diagnosis of retinal diseases such as Diabetic Retinopathy (DR), Glaucoma, and Age-related Macular Degeneration (AMD). Traditional diagnostic workflows, however, often…

Computer Vision and Pattern Recognition · Computer Science 2025-07-31 Faisal Ahmed

Medical image analysis has become a topic under the spotlight in recent years. There is a significant progress in medical image research concerning the usage of machine learning. However, there are still numerous questions and problems…

Image and Video Processing · Electrical Eng. & Systems 2018-05-16 Taha J. Alhindi , Shivam Kalra , Ka Hin Ng , Anika Afrin , Hamid R. Tizhoosh

Microscopic examination of slides prepared from tissue samples is the primary tool for detecting and classifying cancerous lesions, a process that is time-consuming and requires the expertise of experienced pathologists. Recent advances in…

Computer Vision and Pattern Recognition · Computer Science 2024-10-15 Saba Fatema , Brighton Nuwagira , Sayoni Chakraborty , Reyhan Gedik , Baris Coskunuzer

We present a way to use Topological Data Analysis (TDA) for machine learning tasks on grayscale images. We apply persistent homology to generate a wide range of topological features using a point cloud obtained from an image, its natural…

Machine Learning · Computer Science 2019-10-23 Adélie Garin , Guillaume Tauzin

Now that disease-modifying therapies for Alzheimer disease have been approved by regulatory agencies, the early, objective, and accurate clinical diagnosis of AD based on the lowest-cost measurement modalities possible has become an…

Image and Video Processing · Electrical Eng. & Systems 2025-11-13 Faisal Ahmed , Taymaz Akan , Fatih Gelir , Owen T. Carmichael , Elizabeth A. Disbrow , Steven A. Conrad , Mohammad A. N. Bhuiyan

Topological data analysis (TDA) has become a powerful approach over the last twenty years, mainly due to its ability to capture the shape and the geometry inherent in the data. Persistence homology, which is a particular tool in TDA, has…

Neurons and Cognition · Quantitative Biology 2024-01-12 Anass B. El-Yaagoubi , Shuhao Jiao , Moo K. Chung , Hernando Ombao

Type 2 Diabetes (T2D) is a chronic metabolic disorder that can lead to blindness and cardiovascular disease. Information about early stage T2D might be present in retinal fundus images, but to what extent these images can be used for a…

Retinal fundus photography enhancement is important for diagnosing and monitoring retinal diseases. However, early approaches to retinal image enhancement, such as those based on Generative Adversarial Networks (GANs), often struggle to…

Image and Video Processing · Electrical Eng. & Systems 2024-11-05 Xuanzhao Dong , Wenhui Zhu , Xin Li , Guoxin Sun , Yi Su , Oana M. Dumitrascu , Yalin Wang

Early and accurate diagnosis of Alzheimer's disease (AD) remains a critical challenge in neuroimaging-based clinical decision support systems. In this work, we propose a novel hybrid deep learning framework that integrates Topological Data…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Faisal Ahmed

In the realm of medical image fusion, integrating information from various modalities is crucial for improving diagnostics and treatment planning, especially in retinal health, where the important features exhibit differently in different…

Image and Video Processing · Electrical Eng. & Systems 2024-07-22 Xin Tian , Nantheera Anantrasirichai , Lindsay Nicholson , Alin Achim

Despite the remarkable accuracies attained by machine learning classifiers to separate complex datasets in a supervised fashion, most of their operation falls short to provide an informed intuition about the structure of data, and, what is…

Machine Learning · Computer Science 2023-03-09 Aina Ferrà , Gloria Cecchini , Fritz-Pere Nobbe Fisas , Carles Casacuberta , Ignasi Cos

Topological data analysis (TDA) is a relatively new field that is gaining rapid adoption due to its robustness and ability to effectively describe complex datasets by quantifying geometric information. In imaging contexts, TDA typically…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Aaryam Sharma

Optical Coherence Tomography allows ophthalmologist to obtain cross-section imaging of eye retina. Assisted with digital image analysis methods, effective disease detection could be performed. Various methods exist to extract feature from…

Computer Vision and Pattern Recognition · Computer Science 2018-09-11 Kuntoro Adi Nugroho

The histogram of oriented gradients (HOG) is a widely used feature descriptor in computer vision for the purpose of object detection. In the paper, a modified HOG descriptor is described, it uses a lookup table and the method of integral…

Computer Vision and Pattern Recognition · Computer Science 2017-03-21 Chunde Huang , Jiaxiang Huang

In recent years, the preliminary diagnosis of ADHD using EEG has attracted the attention from researchers. EEG, known for its expediency and efficiency, plays a pivotal role in the diagnosis and treatment of ADHD. However, the…

Machine Learning · Computer Science 2024-11-06 Tianming Cai , Guoying Zhao , Junbin Zang , Chen Zong , Zhidong Zhang , Chenyang Xue

In this work we use the persistent homology method, a technique in topological data analysis (TDA), to extract essential topological features from the data space and combine them with deep learning features for classification tasks. In TDA,…

Computer Vision and Pattern Recognition · Computer Science 2023-11-14 Mariana Dória Prata Lima , Gilson Antonio Giraldi , Gastão Florêncio Miranda Junior

In a world abundant with diverse data arising from complex acquisition techniques, there is a growing need for new data analysis methods. In this paper we focus on high-dimensional data that are organized into several hierarchical datasets.…

Machine Learning · Computer Science 2021-04-06 Lior Aloni , Omer Bobrowski , Ronen Talmon

A fundamental challenge in diagnostic imaging is the phenomenon of topological equivalence, where benign and malignant structures share global topology but differ in critical geometric detail, leading to diagnostic errors in both…

Computer Vision and Pattern Recognition · Computer Science 2026-03-05 Mariem Abaach , Ian Morilla

Medical image segmentation is an important task for computer aided diagnosis. Pixelwise manual annotations of large datasets require high expertise and is time consuming. Conventional data augmentations have limited benefit by not fully…

Image and Video Processing · Electrical Eng. & Systems 2020-04-28 Dwarikanath Mahapatra , Behzad Bozorgtabar , Jean-Philippe Thiran , Ling Shao

Retinal lesions play a vital role in the accurate classification of retinal abnormalities. Many researchers have proposed deep lesion-aware screening systems that analyze and grade the progression of retinopathy. However, to the best of our…

Computer Vision and Pattern Recognition · Computer Science 2020-08-17 Taimur Hassan , Muhammad Usman Akram , Naoufel Werghi
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