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Topological data analysis (TDA) uncovers crucial properties of objects in medical imaging. Methods based on persistent homology have demonstrated their advantages in capturing topological features that traditional deep learning methods…

Computer Vision and Pattern Recognition · Computer Science 2024-08-16 Yanfan Zhu , Yash Singh , Khaled Younis , Shunxing Bao , Yuankai Huo

Automatic evaluation of the goodness of Generative Adversarial Networks (GANs) has been a challenge for the field of machine learning. In this work, we propose a distance complementary to existing measures: Topology Distance (TD), the main…

Machine Learning · Computer Science 2020-02-28 Danijela Horak , Simiao Yu , Gholamreza Salimi-Khorshidi

Brain network topology, derived from functional magnetic resonance imaging (fMRI), holds promise for improving Alzheimer's disease (AD) diagnosis. Current methods primarily focus on lower-order topological features, often overlooking the…

Geometric Topology · Mathematics 2025-09-19 Dengyi Zhao , Shanyong Li , Yunping Wang , Chenfei Wang , Zhiheng Zhou , Guiying Yan , Xingqin Qi

This paper presents a comparative analysis of deep learning strategies for detecting hypertensive retinopathy from fundus images, a central task in the HRDC challenge~\cite{qian2025hrdc}. We investigate three distinct approaches: a custom…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Yanqiao Zhu

Gland segmentation is a critical step to quantitatively assess the morphology of glands in histopathology image analysis. However, it is challenging to separate densely clustered glands accurately. Existing deep learning-based approaches…

Image and Video Processing · Electrical Eng. & Systems 2021-10-28 Haotian Wang , Min Xian , Aleksandar Vakanski

We present a fully automatic, graph-based technique for extracting the retinal vascular topology -- that is, how different vessels are connected to each other -- given a single color fundus image. Determining this connectivity is very…

Image and Video Processing · Electrical Eng. & Systems 2022-08-09 Aashis Khanal , Saeid Motevali , Rolando Estrada

Table of contents (ToC) extraction aims to extract headings of different levels in documents to better understand the outline of the contents, which can be widely used for document understanding and information retrieval. Existing works…

Computer Vision and Pattern Recognition · Computer Science 2022-12-07 Pengfei Hu , Zhenrong Zhang , Jianshu Zhang , Jun Du , Jiajia Wu

Accurate bone strength prediction is essential for assessing fracture risk, particularly in aging populations and individuals with osteoporosis. Bone imaging has evolved from X-rays and DXA to clinical computed tomography (CT), and now to…

Quantitative Methods · Quantitative Biology 2025-12-04 John Rick Manzanares , Richard Leslie Abel , Paweł Dłotko

Topological Data Analysis (TDA) allows us to extract powerful topological and higher-order information on the global shape of a data set or point cloud. Tools like Persistent Homology or the Euler Transform give a single complex description…

Algebraic Topology · Mathematics 2025-11-04 Vincent P. Grande , Michael T. Schaub

The Histogram of Oriented Gradient is a widely used image feature, which describes local image directionality based on numerical differentiation. Due to its ill-posed nature, small noise may lead to large errors. Conventional HOG may fail…

Image and Video Processing · Electrical Eng. & Systems 2022-05-12 Jiening Zhu , Harini Veeraraghavan , Larry Norton , Joseph O. Deasy , Allen Tannenbaum

We present our novel deep multi-task learning method for medical image segmentation. Existing multi-task methods demand ground truth annotations for both the primary and auxiliary tasks. Contrary to it, we propose to generate the…

Image and Video Processing · Electrical Eng. & Systems 2022-04-06 Binod Bhattarai , Ronast Subedi , Rebati Raman Gaire , Eduard Vazquez , Danail Stoyanov

To enhance the robustness of the Light Gradient Boosting Machine (LightGBM) algorithm for image classification, a topological data analysis (TDA)-based robustness optimization algorithm for LightGBM, TDA-LightGBM, is proposed to address the…

Machine Learning · Computer Science 2024-06-21 Han Yang , Guangjun Qin , Ziyuan Liu , Yongqing Hu , Qinglong Dai

Accurate prediction of Drug-Target Affinity (DTA) is crucial for reducing experimental costs and accelerating early screening in computational drug discovery. While sequence-based deep learning methods avoid reliance on costly 3D…

Machine Learning · Computer Science 2025-11-03 Minghui Li , Yuanhang Wang , Peijin Guo , Wei Wan , Shengshan Hu , Shengqing Hu

Ocular Myasthenia Gravis (OMG) is a rare and challenging disease to detect in its early stages, but symptoms often first appear in the eye muscles, such as drooping eyelids and double vision. Ocular images can be used for early diagnosis by…

Computer Vision and Pattern Recognition · Computer Science 2024-11-04 Ruiyu Xia , Jianqiang Li , Xi Xu , Guanghui Fu

Modern deep neural networks have shown remarkable performance in medical image classification. However, such networks either emphasize pixel-intensity features instead of fundamental anatomical structures (e.g., those encoded by topological…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Pengfei Gu , Huimin Li , Haoteng Tang , Dongkuan , Xu , Erik Enriquez , DongChul Kim , Bin Fu , Danny Z. Chen

Diabetic retinopathy (DR) grading from fundus images has attracted increasing interest in both academic and industrial communities. Most convolutional neural network (CNN) based algorithms treat DR grading as a classification task via…

Computer Vision and Pattern Recognition · Computer Science 2021-03-19 Yehui Yang , Fangxin Shang , Binghong Wu , Dalu Yang , Lei Wang , Yanwu Xu , Wensheng Zhang , Tianzhu Zhang

In today's world of health care, brain tumor detection has become common. However, the manual brain tumor classification approach is time-consuming. So Deep Convolutional Neural Network (DCNN) is used by many researchers in the medical…

Image and Video Processing · Electrical Eng. & Systems 2024-11-22 Dhananjay Joshi , Bhupesh Kumar Singh , Kapil Kumar Nagwanshi , Nitin S. Choubey

Diabetic retinopathy is an eye-related pathology creating abnormalities and causing visual impairment, proper treatment of which requires identifying irregularities. This research uses a hemorrhage detection method and compares…

Image and Video Processing · Electrical Eng. & Systems 2022-06-03 Tamoor Aziz , Chalie Charoenlarpnopparut , Srijidtra Mahapakulchai

In recent years, graph neural networks (GNNs) have emerged as a potent tool for learning on graph-structured data and won fruitful successes in varied fields. The majority of GNNs follow the message-passing paradigm, where representations…

Machine Learning · Computer Science 2024-08-30 Yurui Lai , Xiaoyang Lin , Renchi Yang , Hongtao Wang

Topological Data Analysis (TDA), an emerging field in investment sciences, harnesses mathematical methods to extract data features based on shape, offering a promising alternative to classical portfolio selection methodologies. We utilize…

Portfolio Management · Quantitative Finance 2026-01-08 Anubha Goel , Amita Sharma , Juho Kanniainen