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Despite the rapid progress of Large Language Models (LLMs), their application in agriculture remains limited due to the lack of domain-specific models, curated datasets, and robust evaluation frameworks. To address these challenges, we…

Artificial Intelligence · Computer Science 2025-08-13 Bo Yang , Yu Zhang , Lanfei Feng , Yunkui Chen , Jianyu Zhang , Xiao Xu , Nueraili Aierken , Yurui Li , Yuxuan Chen , Guijun Yang , Yong He , Runhe Huang , Shijian Li

Purpose: Large Language Models (LLMs) like GPT (Generative Pre-trained Transformer) from OpenAI and LLaMA (Large Language Model Meta AI) from Meta AI are increasingly recognized for their potential in the field of cheminformatics,…

Biomolecules · Quantitative Biology 2024-05-22 Shaghayegh Sadeghi , Alan Bui , Ali Forooghi , Jianguo Lu , Alioune Ngom

Large Language Models (LLMs) such as Gemma-2B have shown strong performance in various natural language processing tasks. However, general-purpose models often lack the domain expertise required for cybersecurity applications. This work…

Cryptography and Security · Computer Science 2026-01-13 Vasanth Iyer , Leonardo Bobadilla , S. S. Iyengar

Large Language Models (LLMs) exhibit remarkable proficiency in addressing a diverse array of tasks within the Natural Language Processing (NLP) domain, with various prompt design strategies significantly augmenting their capabilities.…

Computation and Language · Computer Science 2024-08-05 Xiangyu Zhao , Chengqian Ma

Large-scale pre-trained language models (LLMs) have demonstrated exceptional performance in various natural language processing (NLP) tasks. However, the massive size of these models poses huge challenges for their deployment in real-world…

Computation and Language · Computer Science 2023-10-25 Jiduan Liu , Jiahao Liu , Qifan Wang , Jingang Wang , Xunliang Cai , Dongyan Zhao , Ran Lucien Wang , Rui Yan

This work presents an ontology-integrated large language model (LLM) framework for chemical engineering that unites structured domain knowledge with generative reasoning. The proposed pipeline aligns model training and inference with the…

Machine Learning · Computer Science 2025-12-15 Crystal Su , Kuai Yu , Jingrui Zhang , Mingyuan Shao , Daniel Bauer

Large Language Models (LLMs) have demonstrated substantial progress in biomedical and clinical applications, motivating rigorous evaluation of their ability to answer nuanced, evidence-based questions. We curate a multi-source benchmark…

Computation and Language · Computer Science 2025-09-16 Can Wang , Yiqun Chen

The rapid development of large language models (LLMs) is reshaping operational paradigms across multidisciplinary domains. LLMs' emergent capability to synthesize policy-relevant insights across disciplinary boundaries suggests potential as…

Computers and Society · Computer Science 2025-04-22 Jinghan Ke , Zheng Zhou , Yuxuan Zhao

This study investigates the capabilities of Large Language Models (LLMs), specifically GPT-4, in the context of Binary Reverse Engineering (RE). Employing a structured experimental approach, we analyzed the LLM's performance in interpreting…

Software Engineering · Computer Science 2024-06-12 Saman Pordanesh , Benjamin Tan

Recent advances in Large Language Models (LLMs) have presented new opportunities for integrating Artificial General Intelligence (AGI) into biological research and education. This study evaluated the capabilities of leading LLMs, including…

Computation and Language · Computer Science 2023-11-15 Xinyu Gong , Jason Holmes , Yiwei Li , Zhengliang Liu , Qi Gan , Zihao Wu , Jianli Zhang , Yusong Zou , Yuxi Teng , Tian Jiang , Hongtu Zhu , Wei Liu , Tianming Liu , Yajun Yan

The emergence of Large Language Models (LLMs) has fundamentally transformed natural language processing, making them indispensable across domains ranging from conversational systems to scientific exploration. However, their pre-trained…

Large language models (LLMs) have demonstrated remarkable capabilities in natural language understanding, reasoning, and problem-solving across various domains. However, their ability to perform complex, multi-step reasoning task-essential…

Atomized chemical knowledge, such as functional group information of molecules and reactions, plays a pivotal intermediate role in the reasoning process that connects molecular structures with their properties and reactivities. While large…

Computational Engineering, Finance, and Science · Computer Science 2026-04-15 Zihan Zhao , Ziping Wan , Lu Chen , Xuanze Lin , Shiyang Yu , Situo Zhang , Da Ma , Zichen Zhu , Danyang Zhang , Huayang Wang , Zhongyang Dai , Liyang Wen , Bo Chen , Xin Chen , Kai Yu

Multimodal large language models (MLLMs) have made impressive progress in many applications in recent years. However, chemical MLLMs that can handle cross-modal understanding and generation remain underexplored. To fill this gap, we propose…

Machine Learning · Computer Science 2025-08-05 Qian Tan , Dongzhan Zhou , Peng Xia , Wanhao Liu , Wanli Ouyang , Lei Bai , Yuqiang Li , Tianfan Fu

Large Language Models (LLMs), typified by OpenAI's GPT, have marked a significant advancement in artificial intelligence. Trained on vast amounts of text data, LLMs are capable of understanding and generating human-like text across a…

Artificial Intelligence · Computer Science 2024-10-29 Haochen Zhang , Yuyang Dong , Chuan Xiao , Masafumi Oyamada

We present a modular framework powered by large language models (LLMs) that automates and streamlines key tasks across the early-stage computational drug discovery pipeline. By combining LLM reasoning with domain-specific tools, the…

The performance of large language models (LLMs) on existing reasoning benchmarks has significantly improved over the past years. In response, we present JEEBench, a considerably more challenging benchmark dataset for evaluating the problem…

Computation and Language · Computer Science 2023-10-24 Daman Arora , Himanshu Gaurav Singh , Mausam

High-throughput phenotyping, the automated mapping of patient signs and symptoms to standardized ontology concepts, is essential to gaining value from electronic health records (EHR) in the support of precision medicine. Despite…

Artificial Intelligence · Computer Science 2024-06-24 Syed I. Munzir , Daniel B. Hier , Chelsea Oommen , Michael D. Carrithers

Large language models (LLMs) solve problems more accurately and interpretably when instructed to work out the answer step by step using a ``chain-of-thought'' (CoT) prompt. One can also improve LLMs' performance on a specific task by…

The rapid advancements in large language models (LLMs) have greatly expanded the potential for automated code-related tasks. Two primary methodologies are used in this domain: prompt engineering and fine-tuning. Prompt engineering involves…

Software Engineering · Computer Science 2025-02-21 Jiho Shin , Clark Tang , Tahmineh Mohati , Maleknaz Nayebi , Song Wang , Hadi Hemmati
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