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Embryonic tissues deform across broad spatial and temporal scales and relax stress through active rearrangements. A quantitative link between cell-scale activity, spatial forcing, and emergent tissue-scale mechanics remains incomplete.…

Biological Physics · Physics 2025-12-18 Sahil Islam , Mohd. Suhail Rizvi , Anupam Gupta

Understanding the rules underlying organismal development is a major unsolved problem in biology. Each cell in a developing organism responds to signals in its local environment by dividing, excreting, consuming, or reorganizing, yet how…

Cell Behavior · Quantitative Biology 2025-08-20 Ramya Deshpande , Francesco Mottes , Ariana-Dalia Vlad , Michael P. Brenner , Alma dal Co

Cellular adaptation to environmental changes relies on the dynamic remodeling of subcellular structures. Among these, sarcomere structures are fundamental to the organization and function of the cytoskeletal architecture. In muscle-type…

Cell Behavior · Quantitative Biology 2024-12-17 Yuika Ueda , Shinji Deguchi

Using discrete simulations, we investigate the behavior of a model granular material within an annular shear cell. Specifically, two-dimensional assemblies of disks are placed between two circular walls, the inner one rotating with…

Materials Science · Physics 2009-11-13 Georg Koval , Jean-Noël Roux , Alain Corfdir , François Chevoir

Ductile fracture through void growth and coalescence depends significantly on the plastic anisotropy of the material and on void size, as shown by experiments and/or numerical simulations through several studies. Macroscopic (homogenized)…

Materials Science · Physics 2017-10-11 V. Gallican , J. Hure

Owing to nonlinear viscoelasticity, materials often show characteristic features that resemble those of thixotropy. This issue has been debated in the literature over the past several decades, and several experimental protocols have been…

Soft Condensed Matter · Physics 2021-06-28 Mayank Agarwal , Shweta Sharma , V. Shankar , Yogesh M. Joshi

Active nematic models explain the topological defects and flow patterns observed in epithelial tissues, but the nature of active stress-whether it is extensile or contractile, a key parameter of the theory-is not well established…

Soft Condensed Matter · Physics 2025-11-11 Jan Rozman , Sumesh P. Thampi , Julia M. Yeomans

For the first time the phenomenon of cellular structure coarsening are consistently analysed from the positions of kinetic, hydrodynamic and stochastodynamic theories of nonequilibrium statistical systems. Thereby micro-, meso- and…

Condensed Matter · Physics 2015-06-25 S. B. Goryachev

Compliant environments can mediate interactions between mechanically active cells like fibroblasts. Starting with a phenomenological model for the behaviour of single cells, we use extensive Monte Carlo simulations to predict non-trivial…

Soft Condensed Matter · Physics 2007-05-23 I. B. Bischofs , U. S. Schwarz

Fatigue crack growth is decisive for the design of thin-walled structures such as fuselage shells of air planes. The cold rolling process, used to produce the aluminium sheets this structure is made of, leads to anisotropic mechanical…

Materials Science · Physics 2023-08-03 Martha Kalina , Vanessa Schöne , Boris Spak , Florian Paysan , Eric Breitbarth , Markus Kästner

In this article, we describe the mathematical formulation and the numerical implementation of an effective parametrization of the viscous anisotropy of orthorhombic materials produced by crystallographic preferred orientations (CPO or…

Materials Science · Physics 2023-06-22 Javier Signorelli , Riad Hassani , Andréa Tommasi , Lucan Mameri

Induced by proteins within the cell membrane or by differential growth, heating, or swelling, spontaneous curvatures can drastically affect the morphology of thin bodies and induce mechanical instabilities. Yet, the interaction of…

Soft Condensed Matter · Physics 2018-01-31 Matteo Pezzulla , Norbert Stoop , Mark P. Steranka , Abdikhalaq J. Bade , Douglas P. Holmes

We propose a non-local model for contact guidance and steric hindrance depending on a single external cue, namely the extracellular matrix, that affects in a twofold way the polarization and speed of motion of the cells. We start from a…

Cell Behavior · Quantitative Biology 2022-07-06 Martina Conte , Nadia Loy

Most materials age, and their properties change over time. The aging of materials is reflected in their mechanical responses to external stress and strain, which exhibit logarithmic relaxation and universal power-law creep. Those responses…

Soft Condensed Matter · Physics 2026-01-21 Vikash Pandey

We experimentally and numerically examine stress-dependent electrical transport in granular materials to elucidate the origins of their universal dielectric response. The ac responses of granular systems under varied compressive loadings…

Disordered Systems and Neural Networks · Physics 2019-10-25 Chongpu Zhai , Dorian Hanaor , Gwénaëlle Proust , Yixiang Gan

We develop a 3D porous medium model for sap flow within a tree stem, which consists of a nonlinear parabolic partial differential equation with a suitable transpiration source term. Using an asymptotic analysis, we derive approximate series…

Fluid Dynamics · Physics 2021-06-08 Bebart Maisar Janbek , John M. Stockie

In amorphous solids as in tissues, neighbor exchanges can relax local stresses and allow the material to flow. In this paper, we use an anisotropic vertex model to study T1 rearrangements in polygonal cellular networks. We consider two…

Biological Physics · Physics 2022-11-11 Charlie Duclut , Joris Paijmans , Mandar M. Inamdar , Carl D. Modes , Frank Jülicher

We revisit the problem of describing creep in heterogeneous materials by an effective temperature by considering more realistic (and complex) non-mean-field elastic redistribution kernels. We show first, from theoretical considerations,…

Statistical Mechanics · Physics 2025-07-02 Juan Carlos Verano-Espitia , Jérôme Weiss , David Amitrano , Tero Mäkinen , Mikko Alava

Characterizing structural inhomogeneity is an essential step in understanding the mechanical response of amorphous materials. We introduce a threshold-free measure based on the field of vectors pointing from the center of each particle to…

Soft Condensed Matter · Physics 2016-03-02 Jennifer M. Rieser , Carl P. Goodrich , Andrea J. Liu , Douglas J. Durian

In this paper, we analyse a model for the growth of three-dimensional walled cells. In this model the biomechanical expansion of the cell is coupled with the geometry of its wall. We consider that the density of building material depends on…

Analysis of PDEs · Mathematics 2015-02-20 Vincent Calvez , Laetitia Giraldi
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