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The integration of Large Language Models (LLMs) into healthcare promises to transform medical diagnostics, research, and patient care. Yet, the progression of medical LLMs faces obstacles such as complex training requirements, rigorous…

Machine Learning · Computer Science 2024-04-26 Emre Can Acikgoz , Osman Batur İnce , Rayene Bench , Arda Anıl Boz , İlker Kesen , Aykut Erdem , Erkut Erdem

In-hospital mortality (IHM) prediction for ICU patients is critical for timely interventions and efficient resource allocation. While structured physiological data provides quantitative insights, clinical notes offer unstructured,…

Computation and Language · Computer Science 2024-11-27 Harshavardhan Battula , Jiacheng Liu , Jaideep Srivastava

Large Language models (LLMs) have demonstrated state-of-the-art performance in various natural language processing (NLP) tasks across multiple domains, yet they are prone to shortcut learning and factual inconsistencies. This research…

Computation and Language · Computer Science 2024-04-09 Shreyasi Mandal , Ashutosh Modi

Online medical consultations generate large volumes of conversational health data that often embed protected health information, requiring robust methods to classify data categories and assign risk levels in line with policies and practice.…

Computation and Language · Computer Science 2026-01-16 Yiwei Yan , Hao Li , Hua He , Gong Kai , Zhengyi Yang , Guanfeng Liu

In many use-cases, information is stored in text but not available in structured data. However, extracting data from natural language text to precisely fit a schema, and thus enable querying, is a challenging task. With the rise of…

Databases · Computer Science 2023-10-26 Mohammed Saeed , Nicola De Cao , Paolo Papotti

LLMs have become increasingly capable at accomplishing a range of specialized-tasks and can be utilized to expand equitable access to medical knowledge. Most medical LLMs have involved extensive fine-tuning, leveraging specialized medical…

A crucial step in cohort studies is to extract the required cohort from one or more study datasets. This step is time-consuming, especially when a researcher is presented with a dataset that they have not previously worked with. When the…

Machine Learning · Computer Science 2024-12-17 Purity Mugambi , Alexandra Meliou , Madalina Fiterau

$\textbf{Objectives}$: Large Language Models (LLMs) such as ChatGPT and Med-PaLM have excelled in various medical question-answering tasks. However, these English-centric models encounter challenges in non-English clinical settings,…

Computation and Language · Computer Science 2024-01-31 Jiageng Wu , Xian Wu , Zhaopeng Qiu , Minghui Li , Yingying Zhang , Yefeng Zheng , Changzheng Yuan , Jie Yang

Large language models (LLMs) have shown remarkable progress in encoding clinical knowledge and responding to complex medical queries with appropriate clinical reasoning. However, their applicability in subspecialist or complex medical…

This paper introduces a system that integrates large language models (LLMs) into the clinical trial retrieval process, enhancing the effectiveness of matching patients with eligible trials while maintaining information privacy and allowing…

Information Retrieval · Computer Science 2024-11-01 Georgios Peikos , Pranav Kasela , Gabriella Pasi

With the increasing application of large language models (LLMs) in the medical domain, evaluating these models' performance using benchmark datasets has become crucial. This paper presents a comprehensive survey of various benchmark…

Timely identification and accurate risk stratification of cardiovascular disease (CVD) remain essential for reducing global mortality. While existing prediction models primarily leverage structured data, unstructured clinical notes contain…

Computation and Language · Computer Science 2025-07-16 Haowei Yang , Ziyu Shen , Junli Shao , Luyao Men , Xinyue Han , Jing Dong

Motivational interviewing (MI) promotes behavioural change in substance use disorders. Its fidelity is measured using the Motivational Interviewing Treatment Integrity (MITI) framework. While large language models (LLMs) can potentially…

Computation and Language · Computer Science 2026-03-05 Aishwariya Jha , Prakrithi Shivaprakash , Lekhansh Shukla , Animesh Mukherjee , Prabhat Chand , Pratima Murthy

Query rewriting, the process of transforming queries into semantically equivalent yet more efficient variants, is crucial for database optimization. Existing solutions predominantly rely on either rule-based heuristics or Large Language…

Databases · Computer Science 2026-04-09 Jiahui Li , Tongwang Wu , Yuren Mao , Rong Kang , Tieying Zhang , Yunjun Gao

Clinical problem-solving requires processing of semantic medical knowledge such as illness scripts and numerical medical knowledge of diagnostic tests for evidence-based decision-making. As large language models (LLMs) show promising…

In healthcare, the emphasis on patient safety and the minimization of medical errors cannot be overstated. Despite concerted efforts, many healthcare systems, especially in low-resource regions, still grapple with preventing these errors…

Computation and Language · Computer Science 2023-12-21 M Tran , C Sun

Background: Electronic health records (EHRs) enable machine learning for diagnosis, prognosis, and clinical decision support. However, EHR standards vary by country and hospital, making records often incompatible. This limits large-scale…

Information Retrieval · Computer Science 2026-03-27 Jiawei Zhao , Md Shamim Ahmed , Nicolai Dinh Khang Truong , Verena Schuster , Rudolf Mayer , Richard Röttger

Medical Multimodal Large Language Models (Med-MLLMs) require egocentric clinical intent understanding for real-world deployment, yet existing benchmarks fail to evaluate this critical capability. To address these challenges, we introduce…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Shaonan Liu , Guo Yu , Xiaoling Luo , Shiyi Zheng , Wenting Chen , Jie Liu , Linlin Shen

In this study, we present MedS-Bench, a comprehensive benchmark designed to evaluate the performance of large language models (LLMs) in clinical contexts. Unlike existing benchmarks that focus on multiple-choice question answering,…

Computation and Language · Computer Science 2024-09-06 Chaoyi Wu , Pengcheng Qiu , Jinxin Liu , Hongfei Gu , Na Li , Ya Zhang , Yanfeng Wang , Weidi Xie

Objectieve:This review aims to deliver a comprehensive analysis of Large Language Models (LLMs) utilization in mental health care, evaluating their effectiveness, identifying challenges, and exploring their potential for future application.…