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Objective: Exploit accelerometry data for an automatic, reliable, and prompt detection of spontaneous circulation during cardiac arrest, as this is both vital for patient survival and practically challenging. Methods: We developed a machine…

Signal Processing · Electrical Eng. & Systems 2023-02-13 Wolfgang J. Kern , Simon Orlob , Andreas Bohn , Wolfgang Toller , Jan Wnent , Jan-Thorsten Gräsner , Martin Holler

Cardiac Pacemakers are used to regulate the hearts rhythm and prevent abnormal heart beats. Patients undergo a minimal surgery to get the pacemaker implanted in the body, whereas these devices do have their limitations such as battery life,…

Signal Processing · Electrical Eng. & Systems 2024-09-02 Charan S , Reena Monica P

Phase-rectified signal averaging (PRSA) is a widely used algorithm to analyze nonstationary biomedical time series. The method operates by identifying hinge points in the time series according to prescribed rules, extracting segments…

Statistics Theory · Mathematics 2025-11-04 Jiro Akahori , Joseph Najnudel , Hau-Tieng Wu , Ju-Yi Yen

Sufferers of heart failure disease have a life expectancy of one year and heart transplantation is usually the only guarantee of survival beyond this period. The number of donor hearts available currently is less than 3,000 per annum…

Quantitative Methods · Quantitative Biology 2014-05-13 Mohsen A. Bakouri

Cardiopulmonary resuscitation (CPR) is one of the essential tools to ensure oxygen supply during cardiac arrest. However, the precise effects of chest compression are not quantifiable to this day. This often results in a low quality of…

The exponential synchronization rate is addressed for Kuramoto oscillators in the presence of a pacemaker. When natural frequencies are identical, we prove that synchronization can be ensured even when the phases are not constrained in an…

Systems and Control · Computer Science 2012-09-06 Yongqiang Wang , Francis J. Doyle

We consider the use of a running measure of power spectrum disorder to distinguish between the normal sinus rhythm of the heart and two forms of cardiac arrhythmia: atrial fibrillation and atrial flutter. This spectral entropy measure is…

Quantitative Methods · Quantitative Biology 2009-02-16 Phillip P. A. Staniczenko , Chiu Fan Lee , Nick S. Jones

Received signal strength based respiration rate monitoring is emerging as an alternative non-contact technology. These systems make use of the radio measurements of short-range commodity wireless devices, which vary due to the inhalation…

Signal Processing · Electrical Eng. & Systems 2017-11-28 Hüseyin Yiğitler , Ossi Kaltiokallio , Roland Hostettler , Riku Jäntti , Neal Patwari , Simo Särkkä

We present the first experimental realization of a ratchet cellular automaton (RCA) which has been recently suggested as an alternative approach for performing logical operations with interacting (quasi) particles. Our study was performed…

Soft Condensed Matter · Physics 2009-11-11 Dusan Babic , Clemens Bechinger

A model of the heart tissue as a conductive system with two interacting pacemakers and a refractory time, is proposed. In the parametric space of the model the phase locking areas are investigated in detail. Obtained results allow us to…

Chaotic Dynamics · Physics 2007-05-23 Alexander Loskutov , Sergei Rybalko , Ekaterina Zhuchkova

Cardiac and respiratory rhythms are known to exhibit a modest degree of phase synchronization, which is affected by age, diseases, and other factors. We study the fine temporal structure of this synchrony in healthy young, healthy elderly,…

Tissues and Organs · Quantitative Biology 2021-04-26 Sungwoo Ahn , Jessica Solfest1 , Leonid L Rubchinsky

Formation of feedback loops of excitation waves (reentrant circuit) around non-conducting ventricular scar tissue is a common cause of lethal cardiac arrhythmias, such as ventricular tachycardia. This is typically treated by rapid…

Chaotic Dynamics · Physics 2007-05-23 Sitabhra Sinha , Johannes Breuer

Recently, the Less In More Out device, a fluidically actuated soft total artificial heart was proposed. This device uses arrays of pouch motors to achieve a positive fluidic lever when pneumatically actuated against physiological…

Tissues and Organs · Quantitative Biology 2026-01-08 Marin Lauber , Maziar Arfaee , Mathias Peirlinck

Heart muscle contraction is normally activated by a synchronized Ca release from sarcoplasmic reticulum (SR), a major intracellular Ca store. However, under abnormal conditions Ca leaks from the SR, decreasing heart contraction amplitude…

Subcellular Processes · Quantitative Biology 2023-07-19 Anna Maltsev , Michael Stern , Victor Maltsev

Neural coupled oscillators are a useful building block in numerous models and applications. They were analyzed extensively in theoretical studies and more recently, in biologically realistic simulations of spiking neural networks. The…

Emerging Technologies · Computer Science 2021-09-16 Renate Krause , Joanne J. A. van Bavel , Chenxi Wu , Marc A. Vos , Alain Nogaret , Giacomo Indiveri

Accurate prediction of future risk and disease progression in sepsis is clinically important for early warning and timely intervention in intensive care. However, short-window sepsis prediction remains challenging, because shorter…

Machine Learning · Computer Science 2026-04-17 Honglin Guo , Rihao Chang , He Jiao , Weizhi Nie , Zhongheng Zhang , Yuehao Shen

Background: An increased QT/RR slope is hypothesized to be predictive of sudden cardiac death after myocardial infarction. Previous studies have shown that beta-adrenergic stimulation increases QT/RR slope, but the effects of…

Tissues and Organs · Quantitative Biology 2009-06-30 Tomofumi Kimotsuki , Noriko Niwa , Martin N. Hicks , Michael Dunne , Stuart M. Cobbe , Mari A. Watanabe

Monitoring the respiratory rate is crucial for helping us identify respiratory disorders. Devices for conventional respiratory monitoring are inconvenient and scarcely available. Recent research has demonstrated the ability of non-contact…

Robotics · Computer Science 2022-07-27 Haimiao Mo , Shuai Ding , Shanlin Yang , Athanasios V. Vasilakos , Xi Zheng

Finite element analysis (FEA) forms the cornerstone of modeling cardiac biomechanics but is computationally expensive, limiting its clinical application for digital twin creation, which often requires tens to hundreds of simulations to…

Medical Physics · Physics 2025-04-29 Lei Shi , Yurui Chen , Vijay Vedula

Arrhythmia is an abnormality of the heart's rhythm, caused by problems in the conductive system and resulting in irregular heartbeats. There is increasing evidence that undertaking frequent endurance sports training elevates one's risk of…

Applications · Statistics 2026-01-06 Andrew Nugent , Yi Ting Loo , Jack Buckingham