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Deep learning has revolutionized the early detection of breast cancer, resulting in a significant decrease in mortality rates. However, difficulties in obtaining annotations and huge variations in distribution between training sets and real…

Computer Vision and Pattern Recognition · Computer Science 2024-09-02 Yuxiang Yang , Xinyi Zeng , Pinxian Zeng , Binyu Yan , Xi Wu , Jiliu Zhou , Yan Wang

The rapidly emerging field of computational pathology has the potential to enable objective diagnosis, therapeutic response prediction and identification of new morphological features of clinical relevance. However, deep learning-based…

Image and Video Processing · Electrical Eng. & Systems 2020-05-25 Ming Y. Lu , Drew F. K. Williamson , Tiffany Y. Chen , Richard J. Chen , Matteo Barbieri , Faisal Mahmood

Existing deep learning-based change detection methods try to elaborately design complicated neural networks with powerful feature representations, but ignore the universal domain shift induced by time-varying land cover changes, including…

Computer Vision and Pattern Recognition · Computer Science 2022-08-09 Jia Liu , Wenjie Xuan , Yuhang Gan , Juhua Liu , Bo Du

Learning high-quality, self-supervised, visual representations is essential to advance the role of computer vision in biomedical microscopy and clinical medicine. Previous work has focused on self-supervised representation learning (SSL)…

Computer Vision and Pattern Recognition · Computer Science 2023-03-06 Cheng Jiang , Xinhai Hou , Akhil Kondepudi , Asadur Chowdury , Christian W. Freudiger , Daniel A. Orringer , Honglak Lee , Todd C. Hollon

Domain adaptation techniques aim at adapting a classifier learnt on a source domain to work on the target domain. Exploiting the subspaces spanned by features of the source and target domains respectively is one approach that has been…

Computer Vision and Pattern Recognition · Computer Science 2015-01-19 Anant Raj , Vinay P. Namboodiri , Tinne Tuytelaars

The histopathological analysis of whole-slide images (WSIs) is fundamental to cancer diagnosis but is a time-consuming and expert-driven process. While deep learning methods show promising results, dominant patch-based methods artificially…

Image and Video Processing · Electrical Eng. & Systems 2025-10-08 Alexander Weers , Alexander H. Berger , Laurin Lux , Peter Schüffler , Daniel Rueckert , Johannes C. Paetzold

A key topic in classification is the accuracy loss produced when the data distribution in the training (source) domain differs from that in the testing (target) domain. This is being recognized as a very relevant problem for many computer…

Computer Vision and Pattern Recognition · Computer Science 2014-08-26 Jiaolong Xu , Sebastian Ramos , David Vazquez , Antonio M. Lopez

Population attributes are essential in health for understanding who the data represents and precision medicine efforts. Even within disease infection labels, patients can exhibit significant variability; "fever" may mean something different…

Machine Learning · Statistics 2018-11-28 Vishwali Mhasawade , Nabeel Abdur Rehman , Rumi Chunara

Whole slide images (WSIs) pose unique challenges when training deep learning models. They are very large which makes it necessary to break each image down into smaller patches for analysis, image features have to be extracted at multiple…

Image and Video Processing · Electrical Eng. & Systems 2020-12-02 Ozan Ciga , Tony Xu , Sharon Nofech-Mozes , Shawna Noy , Fang-I Lu , Anne L. Martel

In AI-based histopathology, domain shifts are common and well-studied. However, this research focuses on stain and scanner variations, which do not show the full picture -- shifts may be combinations of other shifts, or "invisible" shifts…

Image and Video Processing · Electrical Eng. & Systems 2023-05-10 Andrew Walker

Unsupervised domain adaptation (UDA) in 3D segmentation tasks presents a formidable challenge, primarily stemming from the sparse and unordered nature of point cloud data. Especially for LiDAR point clouds, the domain discrepancy becomes…

Computer Vision and Pattern Recognition · Computer Science 2024-09-24 Xidong Peng , Runnan Chen , Feng Qiao , Lingdong Kong , Youquan Liu , Yujing Sun , Tai Wang , Xinge Zhu , Yuexin Ma

Weakly Supervised Object Localization (WSOL) models enable joint classification and region-of-interest localization in histology images using only image-class supervision. When deployed in a target domain, distributions shift remains a…

Computer Vision and Pattern Recognition · Computer Science 2026-03-16 Alexis Guichemerre , Banafsheh Karimian , Soufiane Belharbi , Natacha Gillet , Nicolas Thome , Pourya Shamsolmoali , Mohammadhadi Shateri , Luke McCaffrey , Eric Granger

Learning models on one labeled dataset that generalize well on another domain is a difficult task, as several shifts might happen between the data domains. This is notably the case for lidar data, for which models can exhibit large…

Computer Vision and Pattern Recognition · Computer Science 2024-06-27 Björn Michele , Alexandre Boulch , Gilles Puy , Tuan-Hung Vu , Renaud Marlet , Nicolas Courty

Unsupervised Domain Adaptation (UDA) is essential for deploying medical segmentation models across diverse clinical environments. Existing methods are fundamentally limited, suffering from semantically unaware feature alignment that results…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Linkuan Zhou , Yinghao Xia , Yufei Shen , Xiangyu Li , Wenjie Du , Cong Cong , Leyi Wei , Ran Su , Qiangguo Jin

It is commonly recognized that color variations caused by differences in stains is a critical issue for histopathology image analysis. Existing methods adopt color matching, stain separation, stain transfer or the combination of them to…

Image and Video Processing · Electrical Eng. & Systems 2022-08-09 Hai-Li Ye , Da-Han Wang

Deep learning models in computational pathology often fail to generalize across cohorts and institutions due to domain shift. Existing approaches either fail to leverage unlabeled data from the target domain or rely on image-to-image…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Tengyue Zhang , Ruiwen Ding , Luoting Zhuang , Yuxiao Wu , Erika F. Rodriguez , William Hsu

In this paper, we present a novel unsupervised domain adaptation (UDA) method, named Domain Adaptive Relational Reasoning (DARR), to generalize 3D multi-organ segmentation models to medical data collected from different scanners and/or…

Computer Vision and Pattern Recognition · Computer Science 2020-07-14 Shuhao Fu , Yongyi Lu , Yan Wang , Yuyin Zhou , Wei Shen , Elliot Fishman , Alan Yuille

The study of histopathological subtypes is valuable for the personalisation of effective treatment strategies for ovarian cancer. However, increasing diagnostic workloads present a challenge for UK pathology departments, leading to the rise…

Computer Vision and Pattern Recognition · Computer Science 2026-02-18 Marcus Jenkins , Jasenka Mazibrada , Bogdan Leahu , Michal Mackiewicz

Domain shift happens in cross-domain scenarios commonly because of the wide gaps between different domains: when applying a deep learning model well-trained in one domain to another target domain, the model usually performs poorly. To…

Computer Vision and Pattern Recognition · Computer Science 2021-08-19 Munan Ning , Cheng Bian , Dong Wei , Chenglang Yuan , Yaohua Wang , Yang Guo , Kai Ma , Yefeng Zheng

We present a novel approach for unsupervised domain adaptation (UDA) for natural images. A commonly-used objective for UDA schemes is to enhance domain alignment in representation space even if there is a domain shift in the input space.…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Ravi Kant Gupta , Shounak Das , Amit Sethi