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The retina is an essential component of the visual system, and maintaining eyesight depends on the timely and accurate detection of disorders. The early-stage detection and severity classification of Diabetic Retinopathy (DR), a significant…

Diabetic retinopathy (DR), a microvascular complication of diabetes and a leading cause of preventable blindness, is projected to affect more than 130 million individuals worldwide by 2030. Early identification is essential to reduce…

Quantitative Methods · Quantitative Biology 2025-11-12 Jophy Lin

Primary angle closure glaucoma (PACG) is the leading cause of irreversible blindness among Asian people. Early detection of PACG is essential, so as to provide timely treatment and minimize the vision loss. In the clinical practice, PACG is…

Computer Vision and Pattern Recognition · Computer Science 2020-07-21 Munan Ning , Cheng Bian , Donghuan Lu , Hong-Yu Zhou , Shuang Yu , Chenglang Yuan , Yang Guo , Yaohua Wang , Kai Ma , Yefeng Zheng

The use of fundus images for the early screening of eye diseases is of great clinical importance. Due to its powerful performance, deep learning is becoming more and more popular in related applications, such as lesion segmentation,…

Image and Video Processing · Electrical Eng. & Systems 2021-01-26 Tao Li , Wang Bo , Chunyu Hu , Hong Kang , Hanruo Liu , Kai Wang , Huazhu Fu

In this work, we propose a special cascade network for image segmentation, which is based on the U-Net networks as building blocks and the idea of the iterative refinement. The model was mainly applied to achieve higher recognition quality…

Computer Vision and Pattern Recognition · Computer Science 2018-11-22 Artem Sevastopolsky , Stepan Drapak , Konstantin Kiselev , Blake M. Snyder , Jeremy D. Keenan , Anastasia Georgievskaya

Age-related macular degeneration (AMD) is one of the leading causes of irreversible vision impairment in people over the age of 60. This research focuses on semantic segmentation for AMD lesion detection in RGB fundus images, a non-invasive…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Valentyna Starodub , Mantas Lukoševičius

With the rapid development of artificial intelligence (AI) in medical image processing, deep learning in color fundus photography (CFP) analysis is also evolving. Although there are some open-source, labeled datasets of CFPs in the…

WHO has declared that more than 2.2 billion people worldwide are suffering from visual disorders, such as media haze, glaucoma, and drusen. At least 1 billion of these cases could have been either prevented or successfully treated, yet they…

Image and Video Processing · Electrical Eng. & Systems 2024-05-30 Yavuz Selim Inan

Pathologic myopia (PM) is a common blinding retinal degeneration suffered by highly myopic population. Early screening of this condition can reduce the damage caused by the associated fundus lesions and therefore prevent vision loss.…

Image and Video Processing · Electrical Eng. & Systems 2023-05-16 Huihui Fang , Fei Li , Junde Wu , Huazhu Fu , Xu Sun , José Ignacio Orlando , Hrvoje Bogunović , Xiulan Zhang , Yanwu Xu

Cataract remains a leading cause of visual impairment worldwide, and early detection from retinal imaging is critical for timely intervention. We present a deep learning pipeline for cataract classification using the Ocular Disease…

Image and Video Processing · Electrical Eng. & Systems 2025-09-30 MohammadReza Abbaszadeh Bavil Soflaei , Karim SamadZamini

Diabetic macular edema (DME) is a severe complication of diabetes, characterized by thickening of the central portion of the retina due to accumulation of fluid. DME is a significant and common cause of visual impairment in diabetic…

Image and Video Processing · Electrical Eng. & Systems 2024-12-11 Pengyao Qin , Arun J. Thirunavukarasu , Theodoros Arvanitis , Le Zhang

Recently, deep learning has been adopted to the glaucoma classification task with performance comparable to that of human experts. However, a well trained deep learning model demands a large quantity of properly labeled data, which is…

Computer Vision and Pattern Recognition · Computer Science 2020-07-23 Junde Wu , Shuang Yu , Wenting Chen , Kai Ma , Rao Fu , Hanruo Liu , Xiaoguang Di , Yefeng Zheng

Diabetic Retinopathy (DR), a vision-threatening complication of Dia-betes Mellitus (DM), is a major global concern, particularly in India, which has one of the highest diabetic populations. Prolonged hyperglycemia damages reti-nal…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Arpan Maity , Aviroop Pal , MD. Samiul Islam , Tamal Ghosh

Glaucoma is one of the leading causes of irreversible blindness worldwide. Glaucoma prognosis is essential for identifying at-risk patients and enabling timely intervention to prevent blindness. Many existing approaches rely on historical…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Yiran Song , Yikai Zhang , Silvia Orengo-Nania , Nian Wang , Fenglong Ma , Rui Zhang , Yifan Peng , Mingquan Lin

We evaluated whether a glaucoma risk assessment (GRA) model trained on All of Us national data can identify patients at high probability of glaucoma using only systemic electronic health records (EHR) at an independent institution. In this…

Machine Learning · Computer Science 2026-04-24 John Xiang , Rohith Ravindranath , Sophia Y. Wang

Retinal disease diagnosis is critical in preventing vision loss and reducing socioeconomic burdens. Globally, over 2.2 billion people are affected by some form of vision impairment, resulting in annual productivity losses estimated at $411…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Youssef Sabiri , Walid Houmaidi , Amine Abouaomar

Glaucoma is the number one cause of irreversible blindness globally. A major challenge for accurate glaucoma detection and progression forecasting is the bottleneck of limited labeled patients with the state-of-the-art (SOTA) 3D retinal…

Computer Vision and Pattern Recognition · Computer Science 2023-08-28 Yan Luo , Min Shi , Yu Tian , Tobias Elze , Mengyu Wang

Early cancer detection remains one of the most critical challenges in modern healthcare, where delayed diagnosis significantly reduces survival outcomes. Recent advancements in artificial intelligence, particularly deep learning, have…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Emmanuella Avwerosuoghene Oghenekaro

Diabetic Retinopathy (DR) remains a leading cause of preventable blindness, with early detection critical for reducing vision loss worldwide. Over the past decade, deep learning has transformed DR screening, progressing from early…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Muskaan Chopra , Lorenz Sparrenberg , Armin Berger , Sarthak Khanna , Jan H. Terheyden , Rafet Sifa

Eye is the essential sense organ for vision function. Due to the fact that certain eye disorders might result in vision loss, it is essential to diagnose and treat eye diseases early on. By identifying common eye illnesses and performing an…

Computer Vision and Pattern Recognition · Computer Science 2023-07-21 Tareq Babaqi , Manar Jaradat , Ayse Erdem Yildirim , Saif H. Al-Nimer , Daehan Won