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Diabetic Retinopathy (DR) is a serious microvascular complication of diabetes, and one of the leading causes of vision loss worldwide. Although automated detection and grading, with Deep Learning (DL), can reduce the burden on…

Image and Video Processing · Electrical Eng. & Systems 2026-04-06 Shramana Dey , Zahir Khan , T. A. PramodKumar , B. Uma Shankar , Ashis K. Dhara , Ramachandran Rajalakshmi , Rajiv Raman , Sushmita Mitra

Automated optic disc (OD) and optic cup (OC) segmentation in fundus images is relevant to efficiently measure the vertical cup-to-disc ratio (vCDR), a biomarker commonly used in ophthalmology to determine the degree of glaucomatous optic…

Diabetic retinopathy (DR) is a leading cause of preventable blindness, and automated fundus image grading can play an important role in large-scale screening. In this work, we investigate three CLIP-based approaches for five-class DR…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Sungjun Cho

In light of the expanding population, an automated framework of disease detection can assist doctors in the diagnosis of ocular diseases, yields accurate, stable, rapid outcomes, and improves the success rate of early detection. The work…

Image and Video Processing · Electrical Eng. & Systems 2023-08-31 Md. Aiyub Ali , Md. Shakhawat Hossain , Md. Kawar Hossain , Subhadra Soumi Sikder , Sharun Akter Khushbu , Mirajul Islam

Diabetic Macular Edema (DME) is a leading cause of vision loss among patients with Diabetic Retinopathy (DR). While deep learning has shown promising results for automatically detecting this condition from fundus images, its application…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Franco Javier Arellano , José Ignacio Orlando

The growing burden of myopia and retinal diseases necessitates more accessible and efficient eye screening solutions. This study presents a compact, dual-function optical device that integrates fundus photography and refractive error…

Image and Video Processing · Electrical Eng. & Systems 2025-04-29 Boyuan Peng , Jiaju Chen , Yiwei Zhang , Cuiyi Peng , Junyang Li , Jiaming Deng , Peiwu Qin

Diabetic eye disease is one of the fastest growing causes of preventable blindness. With the advent of anti-VEGF (vascular endothelial growth factor) therapies, it has become increasingly important to detect center-involved diabetic macular…

Glaucoma causes irreversible vision loss due to damage to the optic nerve, and there is no cure for glaucoma.OCT imaging modality is an essential technique for assessing glaucomatous damage since it aids in quantifying fundus structures. To…

Computer Vision and Pattern Recognition · Computer Science 2022-08-01 Huihui Fang , Fei Li , Huazhu Fu , Junde Wu , Xiulan Zhang , Yanwu Xu

Parkinson's disease is the world's fastest-growing neurological disorder. Research to elucidate the mechanisms of Parkinson's disease and automate diagnostics would greatly improve the treatment of patients with Parkinson's disease. Current…

Machine Learning · Computer Science 2024-02-20 Charlie Tran , Kai Shen , Kang Liu , Akshay Ashok , Adolfo Ramirez-Zamora , Jinghua Chen , Yulin Li , Ruogu Fang

In recent years, the incidence of vision-threatening eye diseases has risen dramatically, necessitating scalable and accurate screening solutions. This paper presents a comprehensive study on deep learning architectures for the automated…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Mohammad Sadegh Gholizadeh , Amir Arsalan Rezapour

Diagnosing glaucoma progression is critical for limiting irreversible vision loss. A common method for assessing glaucoma progression uses a longitudinal series of visual fields (VF) acquired at regular intervals. VF data are characterized…

Applications · Statistics 2018-05-31 Samuel I. Berchuck , Jean-Claude Mwanza , Joshua L. Warren

Retinal fundus images are widely used for the clinical screening and diagnosis of eye diseases. However, fundus images captured by operators with various levels of experience have a large variation in quality. Low-quality fundus images…

Image and Video Processing · Electrical Eng. & Systems 2020-12-10 Ziyi Shen , Huazhu Fu , Jianbing Shen , Ling Shao

Retinal lesions play a vital role in the accurate classification of retinal abnormalities. Many researchers have proposed deep lesion-aware screening systems that analyze and grade the progression of retinopathy. However, to the best of our…

Computer Vision and Pattern Recognition · Computer Science 2020-08-17 Taimur Hassan , Muhammad Usman Akram , Naoufel Werghi

Convolutional Neural Networks (CNNs) have successfully been used to classify diabetic retinopathy (DR) fundus images in recent times. However, deeper representations in CNNs may capture higher-level semantics at the expense of spatial…

Computer Vision and Pattern Recognition · Computer Science 2021-02-03 Samuel Ofosu Mensah , Bubacarr Bah , Willie Brink

Glaucoma is a leading cause of irreversible blindness. Accurate segmentation of the optic disc (OD) and cup (OC) from fundus images is beneficial to glaucoma screening and diagnosis. Recently, convolutional neural networks demonstrate…

Computer Vision and Pattern Recognition · Computer Science 2019-02-21 Shujun Wang , Lequan Yu , Xin Yang , Chi-Wing Fu , Pheng-Ann Heng

Retinopathy of prematurity (ROP) is an abnormal blood vessel development in the retina of a prematurely-born infant or an infant with low birth weight. ROP is one of the leading causes for infant blindness globally. Early detection of ROP…

Image and Video Processing · Electrical Eng. & Systems 2020-06-15 Xin Guo , Yusuke Kikuchi , Guan Wang , Jinglin Yi , Qiong Zou , Rui Zhou

Automatic clinical diagnosis of retinal diseases has emerged as a promising approach to facilitate discovery in areas with limited access to specialists. Based on the fact that fundus structure and vascular disorders are the main…

Computer Vision and Pattern Recognition · Computer Science 2018-11-05 C. -H. Huck Yang , Fangyu Liu , Jia-Hong Huang , Meng Tian , Hiromasa Morikawa , I-Hung Lin , Yi-Chieh Liu , Hao-Hsiang Yang , Jesper Tegner

Segmentation of blood vessels in retinal images provides early diagnosis of diseases like glaucoma, diabetic retinopathy and macular degeneration. Among these diseases occurrence of Glaucoma is most frequent and has serious ocular…

Computer Vision and Pattern Recognition · Computer Science 2012-09-07 Nilanjan Dey , Anamitra Bardhan Roy , Moumita Pal , Achintya Das

Reliable detection of retinal diseases from fundus images is challenged by the variability in imaging quality, subtle early-stage manifestations, and domain shift across datasets. In this study, we systematically evaluated a Vision…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Jan Benedikt Ruhland , Thorsten Papenbrock , Jan-Peter Sowa , Ali Canbay , Nicole Eter , Bernd Freisleben , Dominik Heider

Fundus photography has been routinely used to document the presence and severity of various retinal degenerative diseases such as age-related macula degeneration, glaucoma, and diabetic retinopathy, for which the fovea, optic disc (OD), and…

Image and Video Processing · Electrical Eng. & Systems 2022-03-02 Huaqing He , Li Lin , Zhiyuan Cai , Xiaoying Tang