Related papers: Modeling Transmission Dynamics of Tuberculosis: Pa…
Tuberculosis persists as a global health crisis, especially in resource-limited populations and remote regions, with more than 10 million individuals newly infected annually. It stands as a stark symbol of inequity in public health.…
Tuberculosis poses a global health risk and Brazil is among the top twenty countries by absolute mortality. However, this epidemiological burden is masked by under-reporting, which impairs planning for effective intervention. We present a…
This study presents a deterministic model to investigate rabies transmission dynamics, incorporating environmental effects and control strategies using optimal control theory. Qualitative and quantitative analyses reveal that the…
Bovine tuberculosis (TB) poses a serious threat for agricultural industry in several countries, it involves potential interactions between wildlife and cattle and creates societal problems in terms of human-wildlife conflict. This study…
The emergence of novel infectious agents presents challenges to statistical models of disease transmission. These challenges arise from limited, poor-quality data and an incomplete understanding of the agent. Moreover, outbreaks manifest…
Bovine tuberculosis (TB) is a chronic disease in cattle that causes a serious food security challenge to the agricultural industry in terms of dairy and meat production. In GB, Scotland has had a risk based surveillance testing policy under…
Regular tuberculosis (TB) screening is required for healthcare employees since they can come into contact with infected patients. TB is a serious, contagious, and potentially deadly disease. Early detection of the disease, even when it is…
We investigate the rates of drug resistance acquisition in a natural population using molecular epidemiological data from Bolivia. First, we study the rate of direct acquisition of double resistance from the double sensitive state within…
Soil-transmitted helminth (STH) infections, one of the most prevalent neglected tropical diseases, pose a significant threat to public health in tropical and subtropical areas. These parasites infect humans and animals through direct…
We propose to use Twitter data as social-spatial sensors. This study deals with the question whether research papers on certain diseases are perceived by people in regions (worldwide) that are especially concerned by the diseases. Since…
Recent work has focused attention on statistical inference for the population distribution of the number of sexual partners based on survey data. The characteristics of these distributions are of interest as components of mathematical…
A central challenge in Human Immunodeficiency Virus (HIV) public health policy lies in determining whether to universally expand treatment access, despite the risk of sub-optimal adherence and consequent drug resistance, or to adopt a more…
We propose and analyse an optimal control problem where the control system is a mathematical model for tuberculosis that considers reinfection. The control functions represent the fraction of early latent and persistent latent individuals…
Tuberculosis (TB), caused by Mycobacterium tuberculosis, remains a critical global health issue, necessitating timely diagnosis and treatment. Current methods for detecting tuberculosis bacilli from bright field microscopic sputum smear…
We study the impact of model parameter uncertainty on optimally mitigating the spread of epidemics. We capture the epidemic spreading process using a susceptible-infected-removed (SIR) epidemic model and consider testing for isolation as…
Disease spread in most biological populations requires the proximity of agents. In populations where the individuals have spatial mobility, the contact graph is generated by the "collision dynamics" of the agents, and thus the evolution of…
We formulate a compartmental model for the propagation of a respiratory disease in a patchy environment. The patches are connected through the mobility of individuals, and we assume that disease transmission and recovery are possible during…
This paper describes methodological details used by WHO in 2015 to estimate TB incidence, prevalence and mortality. Incidence and mortality are disaggregated by HIV status, age and sex. Methods to derive MDR-TB burden indicators are…
In randomized studies evaluating treatments for tuberculosis (TB), individuals are scheduled to be routinely evaluated for the presence of TB using sputum cultures. One important endpoint in such studies is the time of culture conversion,…
In 2014, a major epidemic of human Ebola virus disease emerged in West Africa, where human-to-human transmission has now been been sustained for greater than 10 months. In the summer of 2014, there was great uncertainty about the answers to…