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We share observations and challenges from an ongoing effort to implement Explainable AI (XAI) in a domain-specific workflow for cybersecurity analysts. Specifically, we briefly describe a preliminary case study on the use of XAI for source…

Human-Computer Interaction · Computer Science 2024-08-12 Ashley Suh , Harry Li , Caitlin Kenney , Kenneth Alperin , Steven R. Gomez

When the initial vision of Explainable (XAI) was articulated, the most popular framing was to open the (proverbial) "black-box" of AI so that we could understand the inner workings. With the advent of Large Language Models (LLMs), the very…

Human-Computer Interaction · Computer Science 2024-08-15 Upol Ehsan , Mark O. Riedl

The advancement of machine learning (ML) models has led to the development of ML-based approaches to improve numerous software engineering tasks in software maintenance and evolution. Nevertheless, research indicates that despite their…

Software Engineering · Computer Science 2024-07-22 Md Abdul Awal , Chanchal K. Roy

As machine learning (ML) systems take a more prominent and central role in contributing to life-impacting decisions, ensuring their trustworthiness and accountability is of utmost importance. Explanations sit at the core of these desirable…

Machine Learning · Computer Science 2021-06-16 Sahil Verma , Aditya Lahiri , John P. Dickerson , Su-In Lee

A large set of the explainable Artificial Intelligence (XAI) literature is emerging on feature relevance techniques to explain a deep neural network (DNN) output or explaining models that ingest image source data. However, assessing how XAI…

Artificial Intelligence · Computer Science 2020-12-21 Alexandre Heuillet , Fabien Couthouis , Natalia Díaz-Rodríguez

The applications of Artificial Intelligence (AI) methods especially machine learning techniques have increased in recent years. Classification algorithms have been successfully applied to different problems such as requirement…

Software Engineering · Computer Science 2023-02-13 Behnaz Jamasb , Reza Akbari , Seyed Raouf Khayami

As large language models (LLMs) are increasingly deployed in sensitive domains such as healthcare, law, and education, the demand for transparent, interpretable, and accountable AI systems becomes more urgent. Explainable AI (XAI) acts as a…

Computers and Society · Computer Science 2025-05-28 Francisco Herrera

Deciphering the function of unseen protein sequences is a fundamental challenge with broad scientific impact, yet most existing methods depend on task-specific adapters or large-scale supervised fine-tuning. We introduce the…

Machine Learning · Computer Science 2025-10-14 Xinhui Chen , Zuchao Li , Mengqi Gao , Yufeng Zhang , Chak Tou Leong , Haoyang Li , Jiaqi Chen

The unprecedented performance of machine learning models in recent years, particularly Deep Learning and transformer models, has resulted in their application in various domains such as finance, healthcare, and education. However, the…

Human-Computer Interaction · Computer Science 2023-12-20 Milad Rogha

Explainable Artificial Intelligence (XAI) aims to improve the transparency of machine learning (ML) pipelines. We systematize the increasingly growing (but fragmented) microcosm of studies that develop and utilize XAI methods for defensive…

Cryptography and Security · Computer Science 2023-03-06 Azqa Nadeem , Daniël Vos , Clinton Cao , Luca Pajola , Simon Dieck , Robert Baumgartner , Sicco Verwer

Context: In recent years, leveraging machine learning (ML) techniques has become one of the main solutions to tackle many software engineering (SE) tasks, in research studies (ML4SE). This has been achieved by utilizing state-of-the-art…

Software Engineering · Computer Science 2023-02-14 Ahmad Haji Mohammadkhani , Nitin Sai Bommi , Mariem Daboussi , Onkar Sabnis , Chakkrit Tantithamthavorn , Hadi Hemmati

Nowadays, deep neural networks are widely used in mission critical systems such as healthcare, self-driving vehicles, and military which have direct impact on human lives. However, the black-box nature of deep neural networks challenges its…

Computer Vision and Pattern Recognition · Computer Science 2020-06-24 Arun Das , Paul Rad

As the manufacturing industry advances with sensor integration and automation, the opaque nature of deep learning models in machine learning poses a significant challenge for fault detection and diagnosis. And despite the related predictive…

Artificial Intelligence · Computer Science 2024-06-11 Ahmed Maged , Salah Haridy , Herman Shen

Artificial intelligence (AI), particularly machine learning and deep learning models, has significantly impacted bioinformatics research by offering powerful tools for analyzing complex biological data. However, the lack of interpretability…

Artificial Intelligence · Computer Science 2023-12-12 Zhongliang Zhou , Mengxuan Hu , Mariah Salcedo , Nathan Gravel , Wayland Yeung , Aarya Venkat , Dongliang Guo , Jielu Zhang , Natarajan Kannan , Sheng Li

Explainable Artificial Intelligence (XAI) aims to uncover the inner reasoning of machine learning models. In IoT systems, XAI improves the transparency of models processing sensor data from multiple heterogeneous devices, ensuring end-users…

Computation and Language · Computer Science 2025-08-22 Michele Fiori , Gabriele Civitarese , Priyankar Choudhary , Claudio Bettini

Artificial Intelligence (AI) is rapidly expanding and integrating more into daily life to automate tasks, guide decision making, and enhance efficiency. However, complex AI models, which make decisions without providing clear explanations…

Software Engineering · Computer Science 2025-09-03 Lakshit Arora , Sanjay Surendranath Girija , Shashank Kapoor , Aman Raj , Dipen Pradhan , Ankit Shetgaonkar

Proteins are fundamental biological entities that play a key role in life activities. The amino acid sequences of proteins can be folded into stable 3D structures in the real physicochemical world, forming a special kind of…

Machine Learning · Computer Science 2023-01-04 Lirong Wu , Yufei Huang , Haitao Lin , Stan Z. Li

Predictive business process monitoring (PPM) has been around for several years as a use case of process mining. PPM enables foreseeing the future of a business process through predicting relevant information about how a running process…

Artificial Intelligence · Computer Science 2022-02-17 Ghada Elkhawaga , Mervat Abuelkheir , Manfred Reichert

With the availability of large databases and recent improvements in deep learning methodology, the performance of AI systems is reaching or even exceeding the human level on an increasing number of complex tasks. Impressive examples of this…

Artificial Intelligence · Computer Science 2017-08-29 Wojciech Samek , Thomas Wiegand , Klaus-Robert Müller

Machine learning models are increasingly being used in critical sectors, but their black-box nature has raised concerns about accountability and trust. The field of explainable artificial intelligence (XAI) or explainable machine learning…

Artificial Intelligence · Computer Science 2023-11-14 Ryan Zhou , Ting Hu