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Related papers: Toward the Explainability of Protein Language Mode…

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XAI refers to the techniques and methods for building AI applications which assist end users to interpret output and predictions of AI models. Black box AI applications in high-stakes decision-making situations, such as medical domain have…

Recognizing daily activities with unobtrusive sensors in smart environments enables various healthcare applications. Monitoring how subjects perform activities at home and their changes over time can reveal early symptoms of health issues,…

Human-Computer Interaction · Computer Science 2024-08-14 Michele Fiori , Gabriele Civitarese , Claudio Bettini

In this survey, we address the key challenges in Large Language Models (LLM) research, focusing on the importance of interpretability. Driven by increasing interest from AI and business sectors, we highlight the need for transparency in…

Computation and Language · Computer Science 2024-07-23 Erik Cambria , Lorenzo Malandri , Fabio Mercorio , Navid Nobani , Andrea Seveso

The field of Explainable Artificial Intelligence (XAI) often focuses on users with a strong technical background, making it challenging for non-experts to understand XAI methods. This paper presents "x-[plAIn]", a new approach to make XAI…

Artificial intelligence (AI) has rapidly developed through advancements in computational power and the growth of massive datasets. However, this progress has also heightened challenges in interpreting the "black-box" nature of AI models. To…

Computer Vision and Pattern Recognition · Computer Science 2024-12-19 Shilin Sun , Wenbin An , Feng Tian , Fang Nan , Qidong Liu , Jun Liu , Nazaraf Shah , Ping Chen

Recent advances in Protein Language Models (PLMs) have transformed protein engineering, yet unlike their counterparts in Natural Language Processing (NLP), current PLMs exhibit a fundamental limitation: they excel in either Protein Language…

Computational Engineering, Finance, and Science · Computer Science 2025-09-16 Liuzhenghao Lv , Zongying Lin , Hao Li , Yuyang Liu , Jiaxi Cui , Calvin Yu-Chian Chen , Li Yuan , Yonghong Tian

As AI becomes fundamental in sectors like healthcare, explainable AI (XAI) tools are essential for trust and transparency. However, traditional user studies used to evaluate these tools are often costly, time consuming, and difficult to…

Artificial Intelligence · Computer Science 2024-10-24 Francesco Bombassei De Bona , Gabriele Dominici , Tim Miller , Marc Langheinrich , Martin Gjoreski

Large language models (LLMs) not only exhibit human-like performance but also share computational principles with the brain's language processing mechanisms. While prior research has focused on mapping LLMs' internal representations to…

Computation and Language · Computer Science 2025-04-07 Maryam Rahimi , Yadollah Yaghoobzadeh , Mohammad Reza Daliri

Modern Protein Language Models (PLMs) apply transformer-based model architectures from natural language processing to biological sequences, predicting a variety of protein functions and properties. However, protein language has key…

Machine Learning · Computer Science 2026-02-25 Anna Hart , Chi Han , Jeonghwan Kim , Huimin Zhao , Heng Ji

Explainable Artificial Intelligence (XAI) fills the role of a critical interface fostering interactions between sophisticated intelligent systems and diverse individuals, including data scientists, domain experts, end-users, and more. It…

Deep neural-network-based language models (LMs) are increasingly applied to large-scale protein sequence data to predict protein function. However, being largely black-box models and thus challenging to interpret, current protein LM…

Quantitative Methods · Quantitative Biology 2024-08-06 Mai Ha Vu , Rahmad Akbar , Philippe A. Robert , Bartlomiej Swiatczak , Victor Greiff , Geir Kjetil Sandve , Dag Trygve Truslew Haug

Predictive Process Monitoring (PPM) often uses deep learning models to predict the future behavior of ongoing processes, such as predicting process outcomes. While these models achieve high accuracy, their lack of interpretability…

Artificial Intelligence · Computer Science 2025-06-23 Soobin Chae , Suhwan Lee , Hanna Hauptmann , Hajo A. Reijers , Xixi Lu

Artificial Intelligence (AI) has become essential for analyzing complex data and solving highly-challenging tasks. It is being applied across numerous disciplines beyond computer science, including Food Engineering, where there is a growing…

Across various sectors applications of eXplainableAI (XAI) gained momentum as the increasing black-boxedness of prevailing Machine Learning (ML) models became apparent. In parallel, Large Language Models (LLMs) significantly developed in…

Computation and Language · Computer Science 2025-05-07 Jonas Bokstaller , Julia Altheimer , Julian Dormehl , Alina Buss , Jasper Wiltfang , Johannes Schneider , Maximilian Röglinger

Recently, artificial intelligence and machine learning in general have demonstrated remarkable performances in many tasks, from image processing to natural language processing, especially with the advent of deep learning. Along with…

Machine Learning · Computer Science 2020-10-23 Erico Tjoa , Cuntai Guan

In this paper, we investigate the practical relevance of explainable artificial intelligence (XAI) with a special focus on the producing industries and relate them to the current state of academic XAI research. Our findings are based on an…

Machine Learning · Computer Science 2023-10-13 Thomas Decker , Ralf Gross , Alexander Koebler , Michael Lebacher , Ronald Schnitzer , Stefan H. Weber

Protein language models (PLMs) have advanced computational protein science through large-scale pretraining and scalable architectures. In parallel, reinforcement learning (RL) has broadened exploration and enabled precise multi-objective…

Recent years have seen important advances in the quality of state-of-the-art models, but this has come at the expense of models becoming less interpretable. This survey presents an overview of the current state of Explainable AI (XAI),…

Computation and Language · Computer Science 2025-04-16 Marina Danilevsky , Kun Qian , Ranit Aharonov , Yannis Katsis , Ban Kawas , Prithviraj Sen

The remarkable achievements of Artificial Intelligence (AI) algorithms, particularly in Machine Learning (ML) and Deep Learning (DL), have fueled their extensive deployment across multiple sectors, including Software Engineering (SE).…

Software Engineering · Computer Science 2025-02-06 Sicong Cao , Xiaobing Sun , Ratnadira Widyasari , David Lo , Xiaoxue Wu , Lili Bo , Jiale Zhang , Bin Li , Wei Liu , Di Wu , Yixin Chen

Artificial intelligence models encounter significant challenges due to their black-box nature, particularly in safety-critical domains such as healthcare, finance, and autonomous vehicles. Explainable Artificial Intelligence (XAI) addresses…

Artificial Intelligence · Computer Science 2025-03-14 Melkamu Mersha , Khang Lam , Joseph Wood , Ali AlShami , Jugal Kalita