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Image classification serves as the cornerstone of computer vision, traditionally achieved through discriminative models based on deep neural networks. Recent advancements have introduced classification methods derived from generative…

Computer Vision and Pattern Recognition · Computer Science 2024-12-16 Chunxiao Li , Xiaoxiao Wang , Boming Miao , Chuanlong Xie , Zizhe Wang , Yao Zhu

Multispectral (MS) and panchromatic (PAN) images describe the same land surface, so these images not only have their own advantages, but also have a lot of similar information. In order to separate these similar information and their…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Wenping Ma , Boyou Xue , Mengru Ma , Chuang Chen , Hekai Zhang , Hao Zhu

Drug--target affinity prediction is pivotal for accelerating drug discovery, yet existing methods suffer from significant performance degradation in realistic cold-start scenarios (unseen drugs/targets/pairs), primarily driven by…

Machine Learning · Computer Science 2026-03-17 Zihan Dun , Liuyi Xu , An-Yang Lu , Shuang Li , Yining Qian

Accurate medical image segmentation requires effective modeling of both long-range dependencies and fine-grained boundary details. While transformers mitigate the issue of insufficient semantic information arising from the limited receptive…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Yanxin Li , Hui Wan , Libin Lan

Drug-drug interactions (DDIs) are a major concern in clinical practice, as they can lead to reduced therapeutic efficacy or severe adverse effects. Traditional computational approaches often struggle to capture the complex relationships…

Machine Learning · Computer Science 2025-08-27 Hongbo Liu , Siyi Li , Zheng Yu

Recently, research using point clouds has been increasing with the development of 3D scanner technology. According to this trend, the demand for high-quality point clouds is increasing, but there is still a problem with the high cost of…

Computer Vision and Pattern Recognition · Computer Science 2022-08-24 Hyungjun Lee , Sejoon Lim

Multi-view datasets offer diverse forms of data that can enhance prediction models by providing complementary information. However, the use of multi-view data leads to an increase in high-dimensional data, which poses significant challenges…

Neural and Evolutionary Computing · Computer Science 2024-03-05 Vandad Imani , Carlos Sevilla-Salcedo , Elaheh Moradi , Vittorio Fortino , Jussi Tohka

Drug-drug interaction (DDI) prediction provides a drug combination strategy for systemically effective treatment. Previous studies usually model drug information constrained on a single view such as the drug itself, leading to incomplete…

Biomolecules · Quantitative Biology 2022-03-29 Zimeng Li , Shichao Zhu , Bin Shao , Tie-Yan Liu , Xiangxiang Zeng , Tong Wang

Modern industrial recommendation systems improve recommendation performance by integrating multimodal representations from pre-trained models into ID-based Click-Through Rate (CTR) prediction frameworks. However, existing approaches…

Information Retrieval · Computer Science 2026-04-17 Alin Fan , Hanqing Li , Sihan Lu , Jingsong Yuan , Jiandong Zhang

Modern Web systems such as social media and e-commerce contain rich contents expressed in images and text. Leveraging information from multi-modalities can improve the performance of machine learning tasks such as classification and…

Computer Vision and Pattern Recognition · Computer Science 2021-12-10 Huidong Liu , Shaoyuan Xu , Jinmiao Fu , Yang Liu , Ning Xie , Chien-Chih Wang , Bryan Wang , Yi Sun

Purpose: Combining multi-site diffusion MRI (dMRI) data is hindered by inter-scanner variability, which confounds subsequent analysis. Previous harmonization methods require large, matched or traveling human subjects from multiple sites,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Hwihun Jeong , Qiang Liu , Kathryn E. Keenan , Elisabeth A. Wilde , Walter Schneider , Sudhir Pathak , Anthony Zuccolotto , Lauren J. O'Donnell , Lipeng Ning , Yogesh Rathi

In-silico prediction of repurposable drugs is an effective drug discovery strategy that supplements de-nevo drug discovery from scratch. Reduced development time, less cost and absence of severe side effects are significant advantages of…

Machine Learning · Computer Science 2021-02-23 Sk Mazharul Islam , Sk Md Mosaddek Hossain , Sumanta Ray

Predicting medications is a crucial task in many intelligent healthcare systems. It can assist doctors in making informed medication decisions for patients according to electronic medical records (EMRs). However, medication prediction is a…

Artificial Intelligence · Computer Science 2022-05-02 Yang An , Bo Jin , Xiaopeng Wei

Traditional drug discovery processes are both time-consuming and require extensive professional expertise. With the accumulation of drug-target interaction (DTI) data from experimental studies, leveraging modern machine-learning techniques…

Quantitative Methods · Quantitative Biology 2024-12-12 Shuqi Li , Shufang Xie , Hongda Sun , Yuhan Chen , Tao Qin , Tianjun Ke , Rui Yan

Aggregating pharmaceutical data in the drug-target interaction (DTI) domain has the potential to deliver life-saving breakthroughs. It is, however, notoriously difficult due to regulatory constraints and commercial interests. This work…

Machine Learning · Computer Science 2023-10-19 Gianluca Mittone , Filip Svoboda , Marco Aldinucci , Nicholas D. Lane , Pietro Lio

Visual Similarity plays an important role in many computer vision applications. Deep metric learning (DML) is a powerful framework for learning such similarities which not only generalize from training data to identically distributed test…

Computer Vision and Pattern Recognition · Computer Science 2020-09-11 Timo Milbich , Karsten Roth , Homanga Bharadhwaj , Samarth Sinha , Yoshua Bengio , Björn Ommer , Joseph Paul Cohen

Visual attention has been extensively studied for learning fine-grained features in both facial expression recognition (FER) and Action Unit (AU) detection. A broad range of previous research has explored how to use attention modules to…

Computer Vision and Pattern Recognition · Computer Science 2022-03-24 Xiaotian Li , Zhihua Li , Huiyuan Yang , Geran Zhao , Lijun Yin

Predicting drug-target interaction is key for drug discovery. Recent deep learning-based methods show promising performance but two challenges remain: (i) how to explicitly model and learn local interactions between drugs and targets for…

Machine Learning · Computer Science 2023-01-23 Peizhen Bai , Filip Miljković , Bino John , Haiping Lu

As a critical task in autonomous driving perception systems, 3D object detection is used to identify and track key objects, such as vehicles and pedestrians. However, detecting distant, small, or occluded objects (hard instances) remains a…

Computer Vision and Pattern Recognition · Computer Science 2025-11-14 Feiyang Jia , Caiyan Jia , Ailin Liu , Shaoqing Xu , Qiming Xia , Lin Liu , Lei Yang , Yan Gong , Ziying Song

Accurately predicting the binding affinity between drugs and proteins is an essential step for computational drug discovery. Since graph neural networks (GNNs) have demonstrated remarkable success in various graph-related tasks, GNNs have…

Quantitative Methods · Quantitative Biology 2020-12-18 Jingbo Zhou , Shuangli Li , Liang Huang , Haoyi Xiong , Fan Wang , Tong Xu , Hui Xiong , Dejing Dou