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Related papers: GANs vs. Diffusion Models for virtual staining wit…

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Style transfer is a field with growing interest and use cases in deep learning. Recent work has shown Generative Adversarial Networks(GANs) can be used to create realistic images of virtually stained slide images in digital pathology with…

Computer Vision and Pattern Recognition · Computer Science 2019-06-04 Amal Lahiani , Nassir Navab , Shadi Albarqouni , Eldad Klaiman

Pathological diagnosis relies on the visual inspection of histologically stained thin tissue specimens, where different types of stains are applied to bring contrast to and highlight various desired histological features. However, the…

Medical Physics · Physics 2022-08-18 Xilin Yang , Bijie Bai , Yijie Zhang , Yuzhu Li , Kevin de Haan , Tairan Liu , Aydogan Ozcan

Renal pathology, as the gold standard of kidney disease diagnosis, requires doctors to analyze a series of tissue slices stained by H&E staining and special staining like Masson, PASM, and PAS, respectively. These special staining methods…

Image and Video Processing · Electrical Eng. & Systems 2023-09-19 Tao Ma , Chao Zhang , Min Lu , Lin Luo

Generative Adversarial Networks (GANs) have shown considerable promise for mitigating the challenge of data scarcity when building machine learning-driven analysis algorithms. Specifically, a number of studies have shown that GAN-based…

Computer Vision and Pattern Recognition · Computer Science 2018-11-28 Xiaodan Hu , Audrey G. Chung , Paul Fieguth , Farzad Khalvati , Masoom A. Haider , Alexander Wong

Immunohistochemistry is a valuable diagnostic tool for cancer pathology. However, it requires specialist labs and equipment, is time-intensive, and is difficult to reproduce. Consequently, a long term aim is to provide a digital method of…

Image and Video Processing · Electrical Eng. & Systems 2022-04-15 Christopher D. Walsh , Joanne Edwards , Robert H. Insall

Computer assisted diagnosis in digital pathology is becoming ubiquitous as it can provide more efficient and objective healthcare diagnostics. Recent advances have shown that the convolutional Neural Network (CNN) architectures, a…

Image and Video Processing · Electrical Eng. & Systems 2022-01-05 Sruthi Krishna , Suganthi S. S , Shivsubramani Krishnamoorthy , Arnav Bhavsar

Three-dimensional X-ray histology techniques offer a non-invasive alternative to conventional 2D histology, enabling volumetric imaging of biological tissues without the need for physical sectioning or chemical staining. However, the…

Image and Video Processing · Electrical Eng. & Systems 2025-09-12 Sarah C. Irvine , Christian Lucas , Diana Krüger , Bianca Guedert , Julian Moosmann , Berit Zeller-Plumhoff

Hematoxylin and Eosin (H&E) staining is the cornerstone of histopathology but lacks molecular specificity. While Immunohistochemistry (IHC) provides molecular insights, it is costly and complex, motivating H&E-to-IHC translation as a…

Image and Video Processing · Electrical Eng. & Systems 2025-09-22 Erik Großkopf , Valay Bundele , Mehran Hosseinzadeh , Hendrik P. A. Lensch

Deep learning-based virtual staining was developed to introduce image contrast to label-free tissue sections, digitally matching the histological staining, which is time-consuming, labor-intensive, and destructive to tissue. Standard…

Image and Video Processing · Electrical Eng. & Systems 2022-10-31 Yijie Zhang , Luzhe Huang , Tairan Liu , Keyi Cheng , Kevin de Haan , Yuzhu Li , Bijie Bai , Aydogan Ozcan

With the advent of digital scanners and deep learning, diagnostic operations may move from a microscope to a desktop. Hematoxylin and Eosin (H&E) staining is one of the most frequently used stains for disease analysis, diagnosis, and…

Computer Vision and Pattern Recognition · Computer Science 2023-08-28 Shikha Dubey , Tushar Kataria , Beatrice Knudsen , Shireen Y. Elhabian

Deep generative models have been applied to multiple applications in image-to-image translation. Generative Adversarial Networks and Diffusion Models have presented impressive results, setting new state-of-the-art results on these tasks.…

Computer Vision and Pattern Recognition · Computer Science 2024-02-26 Sagar Saxena , Mohammad Nayeem Teli

Despite the growing availability of high-quality public datasets, the lack of training samples is still one of the main challenges of deep-learning for skin lesion analysis. Generative Adversarial Networks (GANs) appear as an enticing…

Image and Video Processing · Electrical Eng. & Systems 2021-04-22 Alceu Bissoto , Eduardo Valle , Sandra Avila

Magnetic Resonance Imaging (MRI) enables the acquisition of multiple image contrasts, such as T1-weighted (T1w) and T2-weighted (T2w) scans, each offering distinct diagnostic insights. However, acquiring all desired modalities increases…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Andrea Moschetto , Lemuel Puglisi , Alec Sargood , Pierluigi Dell'Acqua , Francesco Guarnera , Sebastiano Battiato , Daniele Ravì

Diffusion Generative Models (DGM) have rapidly surfaced as emerging topics in the field of computer vision, garnering significant interest across a wide array of deep learning applications. Despite their high computational demand, these…

Image and Video Processing · Electrical Eng. & Systems 2024-11-26 Denisha Thakkar , Vincent Quoc-Huy Trinh , Sonal Varma , Samira Ebrahimi Kahou , Hassan Rivaz , Mahdi S. Hosseini

An unpaired image-to-image (I2I) translation technique seeks to find a mapping between two domains of data in a fully unsupervised manner. While initial solutions to the I2I problem were provided by generative adversarial neural networks…

Computer Vision and Pattern Recognition · Computer Science 2023-09-26 Dmitrii Torbunov , Yi Huang , Huan-Hsin Tseng , Haiwang Yu , Jin Huang , Shinjae Yoo , Meifeng Lin , Brett Viren , Yihui Ren

We present a novel method for exemplar-based image translation, called matching interleaved diffusion models (MIDMs). Most existing methods for this task were formulated as GAN-based matching-then-generation framework. However, in this…

Computer Vision and Pattern Recognition · Computer Science 2023-03-30 Junyoung Seo , Gyuseong Lee , Seokju Cho , Jiyoung Lee , Seungryong Kim

Histopathological cancer diagnosis is based on visual examination of stained tissue slides. Hematoxylin and eosin (H\&E) is a standard stain routinely employed worldwide. It is easy to acquire and cost effective, but cells and tissue…

Computer Vision and Pattern Recognition · Computer Science 2022-07-12 Zhaoyang Xu , Xingru Huang , Carlos Fernández Moro , Béla Bozóky , Qianni Zhang

Adversarial Imitation Learning is traditionally framed as a two-player zero-sum game between a learner and an adversarially chosen cost function, and can therefore be thought of as the sequential generalization of a Generative Adversarial…

Machine Learning · Computer Science 2025-03-04 Runzhe Wu , Yiding Chen , Gokul Swamy , Kianté Brantley , Wen Sun

Recently, Generative Adversarial Networks (GANs) have emerged as a popular alternative for modeling complex high dimensional distributions. Most of the existing works implicitly assume that the clean samples from the target distribution are…

Machine Learning · Statistics 2019-02-14 Mohammadreza Soltani , Swayambhoo Jain , Abhinav Sambasivan

Generative Adversarial Networks (GANs) have been shown to produce realistically looking synthetic images with remarkable success, yet their performance seems less impressive when the training set is highly diverse. In order to provide a…

Machine Learning · Computer Science 2018-08-31 Matan Ben-Yosef , Daphna Weinshall