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Objective: Quantitative real-time PCR is widely used for gene expression analysis, yet inconsistencies in data storage and reporting limit reproducibility. While MIQE guidelines define the minimal information required for publication, they…

Quantitative Methods · Quantitative Biology 2025-10-16 Mirco Castoldi

Quantum programs are designed to run on quantum computers, leveraging quantum circuits to solve problems that are intractable for classical machines. As quantum computing advances, ensuring the reliability of quantum programs has become…

Software Engineering · Computer Science 2025-09-08 Tiancheng Jin , Shangzhou Xia , Jianjun Zhao

Ubiquitous noises in quantum systems remain a key obstacle to building quantum computers, necessitating the use of quantum error correction codes. Recently, error-correcting codes tailored for noise-biased systems have been shown to offer…

Unlike code completion, debugging requires localizing faults and applying targeted edits. We observe that frontier LLMs often regenerate correct but over-edited solutions during debugging. To evaluate how far LLMs are from precise…

Software Engineering · Computer Science 2026-05-19 Wang Bill Zhu , Miaosen Chai , Shangshang Wang , Yejia Liu , Song Bian , Honghua Dong , Willie Neiswanger , Robin Jia

Quantum error correction (QEC) enables reliable computation on noisy hardware by encoding logical information across many physical qubits and periodically measuring parities to detect errors. A decoder is the classical algorithm that uses…

Programming Languages · Computer Science 2026-03-23 Abtin Molavi , Feras Saad , Aws Albarghouthi

Digital quantum computing promises to offer computational capabilities beyond the reach of classical systems, yet its capabilities are often challenged by scarce quantum resources. A critical bottleneck in this context is how to load…

Quantum Physics · Physics 2026-03-02 Kaining Zhang , Xinbiao Wang , Yuxuan Du , Min-Hsiu Hsieh , Dacheng Tao

Quantum computers promise to solve certain problems more efficiently than their digital counterparts. A major challenge towards practically useful quantum computing is characterizing and reducing the various errors that accumulate during an…

Motivated by realistic hardware considerations of the pre-fault-tolerant era, we comprehensively study the impact of uncorrected noise on quantum circuits. We first show that any noise `truncates' most quantum circuits to effectively…

(Abridged.) This thesis investigates scalable fault-tolerant quantum computation through the development of bosonic quantum codes, quantum LDPC codes, and decoding protocols that connect continuous-variable and discrete-variable error…

Quantum Physics · Physics 2025-12-18 Timo Hillmann

Many current quantum error-correcting codes that achieve full fault tolerance suffer from having low ratios of logical to physical qubits and significant overhead. This makes them difficult to implement on current noisy intermediate-scale…

Quantum Physics · Physics 2026-05-22 Christopher Gerhard , Todd A. Brun

Quantum noise is a central challenge in quantum computing across many applications. Extensive work has examined how qubits couple to their environment, leading to decoherence and relaxation, which is irreversible. Current studies focus on…

Quantum Physics · Physics 2026-04-30 Yunos El Kaderi , Andreas Honecker , Iryna Andriyanova

Automatically generated code is gaining traction recently, owing to the prevalence of Large Language Models (LLMs). Further, the AlphaProof initiative has demonstrated the possibility of using AI for general mathematical reasoning.…

Software Engineering · Computer Science 2026-04-14 Haoxin Tu , Huan Zhao , Yahui Song , Mehtab Zafar , Ruijie Meng , Abhik Roychoudhury

Quantum computation promises to advance a wide range of computational tasks. However, current quantum hardware suffers from noise and is too small for error correction. Thus, accurately utilizing noisy quantum computers strongly relies on…

Optimization and Control · Mathematics 2024-12-16 Friedrich Wagner , Daniel J. Egger , Frauke Liers

The potential of quantum computers to outperform classical ones in practically useful tasks remains challenging in the near term due to scaling limitations and high error rates of current quantum hardware. While quantum error correction…

Program debloating aims to remove unused code to reduce performance overhead, attack surfaces, and maintenance costs. Over time, debloating has evolved across multiple layers (container, library, and application), each building on the…

Software Engineering · Computer Science 2026-04-22 Muhammad Bilal , Moiz Ali , Mohit Kumar , Fareed Zaffar , Fahad Shaon , Ashish Gehani , Sazzadur Rahaman

The hope of the quantum computing field is that quantum architectures are able to scale up and realize fault-tolerant quantum computing. Due to engineering challenges, such ''cheap'' error correction may be decades away. In the meantime, we…

Quantum Physics · Physics 2025-02-17 Rutuja Kshirsagar , Amara Katabarwa , Peter D. Johnson

Quantum low-density parity-check codes are promising candidates towards scalable fault-tolerant quantum computation. Among these, bivariate bicycle (BB) codes offer superior encoding rates and large code distance compared to surface codes.…

It is hard to achieve a theoretical quantum advantage on NISQ devices. Besides the attempts to reduce error using error mitigation and dynamical decoupling, small quantum error correction and fault-tolerant schemes that reduce the high…

Quantum Physics · Physics 2020-12-04 Anirudh Lanka

The LogQ algorithm encodes Quadratic Unconstrained Binary Optimization (QUBO) problems, which are often encountered in the industry (portfolio optimization, fleet optimization, charging stations, etc.). It was developed within the framework…

Optimization and Control · Mathematics 2026-04-15 Jérémie Messud , Yagnik Chatterjee

We realize a suite of logical operations on a distance-two logical qubit stabilized using repeated error detection cycles. Logical operations include initialization into arbitrary states, measurement in the cardinal bases of the Bloch…