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Next-generation multimodal foundation models capable of any-to-any cross-modal generation and multi-turn interaction will serve as core components of artificial general intelligence systems, playing a pivotal role in human-machine…

Computation and Language · Computer Science 2025-10-17 Run Luo , Xiaobo Xia , Lu Wang , Longze Chen , Renke Shan , Jing Luo , Min Yang , Tat-Seng Chua

Action, cognition, emotion and perception can be mapped in the brain by using set of techniques. Translating unimodal concepts from one modality to another is an important step towards understanding the neural mechanisms. This paper…

Other Computer Science · Computer Science 2012-12-18 Revati Shriram , Dr. M. Sundhararajan , Nivedita Daimiwal

Machine learning provides a valuable tool for analyzing high-dimensional functional neuroimaging data, and is proving effective in predicting various neurological conditions, psychiatric disorders, and cognitive patterns. In functional…

Machine Learning · Computer Science 2024-11-25 Anwar Said , Roza G. Bayrak , Tyler Derr , Mudassir Shabbir , Daniel Moyer , Catie Chang , Xenofon Koutsoukos

Existing deep learning models for functional MRI-based classification have limitations in network architecture determination (relying on experience) and feature space fusion (mostly simple concatenation, lacking mutual learning). Inspired…

Machine Learning · Computer Science 2025-08-19 Xiangxiang Cui , Min Zhao , Dongmei Zhi , Shile Qi , Vince D Calhoun , Jing Sui

Multimodal functional neuroimaging enables systematic analysis of brain mechanisms and provides discriminative representations for brain-computer interface (BCI) decoding. However, its acquisition is constrained by high costs and…

Computer Vision and Pattern Recognition · Computer Science 2025-06-04 Weiheng Yao , Xuhang Chen , Shuqiang Wang

Precise prognostic modeling of glioblastoma (GBM) under varying treatment interventions is essential for optimizing clinical outcomes. While generative AI has shown promise in simulating GBM evolution, existing methods typically treat…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Chenhui Wang , Boyun Zheng , Liuxin Bao , Zhihao Peng , Peter Y. M. Woo , Hongming Shan , Yixuan Yuan

The anatomical structure of the brain can be observed via non-invasive techniques such as diffusion imaging. However, these are imperfect because they miss connections that are actually known to exist, especially long range…

Neurons and Cognition · Quantitative Biology 2015-02-25 Somwrita Sarkar , Sanjay Chawla , Donna Xu

Psychedelics, such as psilocybin, reorganise large-scale brain connectivity, yet how these changes are reflected across electrophysiological (electroencephalogram, EEG) and haemodynamic (functional magnetic resonance imaging, fMRI) networks…

Neurons and Cognition · Quantitative Biology 2025-11-25 Sin-Yee Yap , Fuad Noman , Junn Yong Loo , Devon Stoliker , Moein Khajehnejad , Raphaël C. -W. Phan , David L. Dowe , Adeel Razi , Chee-Ming Ting

Functional connectivity (FC) studies have demonstrated the overarching value of studying the brain and its disorders through the undirected weighted graph of fMRI correlation matrix. Most of the work with the FC, however, depends on the way…

Neurons and Cognition · Quantitative Biology 2021-12-09 Usman Mahmood , Zening Fu , Vince Calhoun , Sergey Plis

In recent years, the rapid development of neuroimaging technology has been providing many powerful tools for cognitive neuroscience research. Among them, the functional magnetic resonance imaging (fMRI), which has high spatial resolution,…

Human-Computer Interaction · Computer Science 2018-08-20 Yang Wang , Dongrui Wu

Clinical diagnostic workups typically follow a modality escalation pathway: after initial clinical evaluation, clinicians begin with routine structural imaging (e.g., MRI), selectively add sequences such as FLAIR or T2 to refine the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Guangqian Yang , Tong Ding , Wenlong Hou , Yue Xun , Ye Du , Qian Niu , Shujun Wang

Current multi-modal image fusion methods typically rely on task-specific models, leading to high training costs and limited scalability. While generative methods provide a unified modeling perspective, they often suffer from slow inference…

Computer Vision and Pattern Recognition · Computer Science 2025-11-19 Huayi Zhu , Xiu Shu , Youqiang Xiong , Qiao Liu , Rui Chen , Di Yuan , Xiaojun Chang , Zhenyu He

Finding interpretable biomechanical models can provide insight into the functionality of organs with regard to physiology and disease. However, identifying broadly applicable dynamical models for in vivo tissue remains challenging. In this…

Mechanistic models of progressive neurodegeneration offer great potential utility for clinical use and novel treatment development. Toward this end, several connectome-informed models of neuroimaging biomarkers have been proposed. However,…

Quantitative Methods · Quantitative Biology 2025-08-15 Daniel Semchin , Emile d'Angremont , Marco Lorenzi , Boris Gutman

Foundation models can be disruptive for future AI development by scaling up deep learning in terms of model size and training data's breadth and size. These models achieve state-of-the-art performance (often through further adaptation) on a…

Artificial Intelligence · Computer Science 2022-12-20 Johannes Schneider

The field of computational pathology has recently seen rapid advances driven by the development of modern vision foundation models (FMs), typically trained on vast collections of pathology images. Recent studies demonstrate that increasing…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Mikhail Karasikov , Joost van Doorn , Nicolas Känzig , Melis Erdal Cesur , Hugo Mark Horlings , Robert Berke , Fei Tang , Sebastian Otálora

The development of foundation models for brain MRI depends critically on the scale, diversity, and consistency of available data, yet systematic assessments of these factors remain scarce. In this study, we analyze 54 publicly accessible…

Computer Vision and Pattern Recognition · Computer Science 2025-10-24 Minh Sao Khue Luu , Margaret V. Benedichuk , Ekaterina I. Roppert , Roman M. Kenzhin , Bair N. Tuchinov

Mapping from functional connectivity (FC) to structural connectivity (SC) can facilitate multimodal brain network fusion and discover potential biomarkers for clinical implications. However, it is challenging to directly bridge the reliable…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Qiankun Zuo , Bangjun Lei , Wanyu Qiu , Changhong Jing , Jin Hong , Shuqiang Wang

Magnetic resonance imaging (MRI) has played a crucial role in fetal neurodevelopmental research. Structural annotations of MR images are an important step for quantitative analysis of the developing human brain, with Deep Learning providing…

Foundation models, especially those using transformers as backbones, have gained significant popularity, particularly in language and language-vision tasks. However, large foundation models are typically trained on high-quality data, which…

Signal Processing · Electrical Eng. & Systems 2024-04-30 Cheng Ding , Zhicheng Guo , Zhaoliang Chen , Randall J Lee , Cynthia Rudin , Xiao Hu