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Diffusion models have enabled remarkably high-quality medical image generation, yet it is challenging to enforce anatomical constraints in generated images. To this end, we propose a diffusion model-based method that supports…

Image and Video Processing · Electrical Eng. & Systems 2024-06-21 Nicholas Konz , Yuwen Chen , Haoyu Dong , Maciej A. Mazurowski

Diffusion models, a powerful and universal generative AI technology, have achieved tremendous success in computer vision, audio, reinforcement learning, and computational biology. In these applications, diffusion models provide flexible…

Machine Learning · Computer Science 2024-04-12 Minshuo Chen , Song Mei , Jianqing Fan , Mengdi Wang

Deep learning models are prone to learning shortcut solutions to problems using spuriously correlated yet irrelevant features of their training data. In high-risk applications such as medical image analysis, this phenomenon may prevent…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Christopher Boland , Sotirios Tsaftaris , Sonia Dahdouh

The discovery of inorganic crystal structures with targeted properties is a significant challenge in materials science. Generative models, especially state-of-the-art diffusion models, offer the promise of modeling complex data…

Real-world datasets are often biased with respect to key demographic factors such as race and gender. Due to the latent nature of the underlying factors, detecting and mitigating bias is especially challenging for unsupervised machine…

Machine Learning · Computer Science 2020-07-01 Kristy Choi , Aditya Grover , Trisha Singh , Rui Shu , Stefano Ermon

Data-driven dynamics prediction often fails under environmental shifts, while traditional fine-tuning remains computationally prohibitive for hardware-constrained or data-scarce applications. We propose DynaDiff, a generative meta-learning…

Computational Engineering, Finance, and Science · Computer Science 2026-05-05 Ruikun Li , Huandong Wang , Jingtao Ding , Yuan Yuan , Qingmin Liao , Yong Li

Diffusion-based algorithms have emerged as promising techniques for weight generation. However, existing solutions are limited by two challenges: generalizability and local target assignment. The former arises from the inherent lack of…

Machine Learning · Computer Science 2025-05-20 Yunchuan Guan , Yu Liu , Ke Zhou , Zhiqi Shen , Jenq-Neng Hwang , Lei Li

While large-scale language models (LMs) are able to imitate the distribution of natural language well enough to generate realistic text, it is difficult to control which regions of the distribution they generate. This is especially…

Computation and Language · Computer Science 2020-10-23 Ben Krause , Akhilesh Deepak Gotmare , Bryan McCann , Nitish Shirish Keskar , Shafiq Joty , Richard Socher , Nazneen Fatema Rajani

Recently, large-scale diffusion models, e.g., Stable diffusion and DallE2, have shown remarkable results on image synthesis. On the other hand, large-scale cross-modal pre-trained models (e.g., CLIP, ALIGN, and FILIP) are competent for…

Computer Vision and Pattern Recognition · Computer Science 2023-08-21 Runhui Huang , Jianhua Han , Guansong Lu , Xiaodan Liang , Yihan Zeng , Wei Zhang , Hang Xu

Medical image data is less accessible than in other domains due to privacy and regulatory constraints. In addition, labeling requires costly, time-intensive manual image annotation by clinical experts. To overcome these challenges,…

Image and Video Processing · Electrical Eng. & Systems 2025-07-11 Fangyijie Wang , Kevin Whelan , Félix Balado , Kathleen M. Curran , Guénolé Silvestre

Recent progress in generative AI, primarily through diffusion models, presents significant challenges for real-world deepfake detection. The increased realism in image details, diverse content, and widespread accessibility to the general…

Computer Vision and Pattern Recognition · Computer Science 2024-04-03 Chaitali Bhattacharyya , Hanxiao Wang , Feng Zhang , Sungho Kim , Xiatian Zhu

Radiation response in cancer is shaped by complex, patient specific biology, yet current treatment strategies often rely on uniform dose prescriptions without accounting for tumor heterogeneity. In this study, we introduce a meta learning…

Medical Physics · Physics 2025-08-12 Hao Peng , Yuanyuan Zhang , Steve Jiang , Robert Timmerman , John Minna

Self-supervised learning is a popular and powerful method for utilizing large amounts of unlabeled data, for which a wide variety of training objectives have been proposed in the literature. In this study, we perform a Bayesian analysis of…

Machine Learning · Computer Science 2023-02-08 Emanuele Sansone , Robin Manhaeve

Skin diseases affect millions of people worldwide, across all ethnicities. Increasing diagnosis accessibility requires fair and accurate segmentation and classification of dermatology images. However, the scarcity of annotated medical…

Computer Vision and Pattern Recognition · Computer Science 2023-07-24 Héctor Carrión , Narges Norouzi

Few-shot learning is a standard practice in most deep learning based histopathology image segmentation, given the relatively low number of digitized slides that are generally available. While many models have been developed for domain…

Image and Video Processing · Electrical Eng. & Systems 2021-10-01 Zheng Yuan , Andre Esteva , Ran Xu

In the rapidly advancing realm of visual generation, diffusion models have revolutionized the landscape, marking a significant shift in capabilities with their impressive text-guided generative functions. However, relying solely on text for…

Computer Vision and Pattern Recognition · Computer Science 2026-01-09 Pu Cao , Feng Zhou , Qing Song , Lu Yang

Diffusion models are the mainstream approach for time series generation tasks. However, existing diffusion models for time series generation require retraining the entire framework to introduce specific conditional guidance. There also…

Machine Learning · Computer Science 2025-09-25 Mingchun Sun , Rongqiang Zhao , Hengrui Hu , Songyu Ding , Jie Liu

The adoption of diagnosis and prognostic algorithms in healthcare has led to concerns about the perpetuation of bias against disadvantaged groups of individuals. Deep learning methods to detect and mitigate bias have revolved around…

Diffusion models have demonstrated impressive capabilities in synthesizing diverse content. However, despite their high-quality outputs, these models often perpetuate social biases, including those related to gender and race. These biases…

Computer Vision and Pattern Recognition · Computer Science 2025-03-27 Yingdong Shi , Changming Li , Yifan Wang , Yongxiang Zhao , Anqi Pang , Sibei Yang , Jingyi Yu , Kan Ren

Published studies have suggested the bias of automated face-based gender classification algorithms across gender-race groups. Specifically, unequal accuracy rates were obtained for women and dark-skinned people. To mitigate the bias of…

Computer Vision and Pattern Recognition · Computer Science 2022-08-18 Sreeraj Ramachandran , Ajita Rattani