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We show that diffusion models can achieve image sample quality superior to the current state-of-the-art generative models. We achieve this on unconditional image synthesis by finding a better architecture through a series of ablations. For…

Machine Learning · Computer Science 2021-06-02 Prafulla Dhariwal , Alex Nichol

Accurate medical image segmentation is crucial for precise anatomical delineation. Deep learning models like U-Net have shown great success but depend heavily on large datasets and struggle with domain shifts, complex structures, and…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Hantao Zhang , Yuhe Liu , Jiancheng Yang , Weidong Guo , Xinyuan Wang , Pascal Fua

Diffusion models are a class of generative models that have demonstrated remarkable success in tasks such as image generation. However, one of the bottlenecks of these models is slow sampling due to the delay before the onset of trajectory…

Machine Learning · Statistics 2025-12-25 Li Cunzhi , Louis Kang , Hideaki Shimazaki

Collective insights from a group of experts have always proven to outperform an individual's best diagnostic for clinical tasks. For the task of medical image segmentation, existing research on AI-based alternatives focuses more on…

Computer Vision and Pattern Recognition · Computer Science 2023-04-11 Aimon Rahman , Jeya Maria Jose Valanarasu , Ilker Hacihaliloglu , Vishal M Patel

Deep learning model effectiveness in classification tasks is often challenged by the quality and quantity of training data whenever they are affected by strong spurious correlations between specific attributes and target labels. This…

Current machine learning has made great progress on computer vision and many other fields attributed to the large amount of high-quality training samples, while it does not work very well on genomic data analysis, since they are notoriously…

Machine Learning · Computer Science 2020-09-04 Ziyi Yang , Jun Shu , Yong Liang , Deyu Meng , Zongben Xu

Neural networks struggle with image classification when biases are learned and misleads correlations, affecting their generalization and performance. Previous methods require attribute labels (e.g. background, color) or utilizes Generative…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Donggeun Ko , Dongjun Lee , Namjun Park , Wonkyeong Shim , Jaekwang Kim

Artificial intelligence (AI) systems, particularly those based on deep learning models, have increasingly achieved expert-level performance in medical applications. However, there is growing concern that such AI systems may reflect and…

Computation and Language · Computer Science 2025-04-25 Xiuying Chen , Tairan Wang , Juexiao Zhou , Zirui Song , Xin Gao , Xiangliang Zhang

Learning-based Text-to-Image (TTI) models like Stable Diffusion have revolutionized the way visual content is generated in various domains. However, recent research has shown that nonnegligible social bias exists in current state-of-the-art…

Computer Vision and Pattern Recognition · Computer Science 2024-02-23 Ruifei He , Chuhui Xue , Haoru Tan , Wenqing Zhang , Yingchen Yu , Song Bai , Xiaojuan Qi

Despite continued advancement in recent years, deep neural networks still rely on large amounts of training data to avoid overfitting. However, labeled training data for real-world applications such as healthcare is limited and difficult to…

Data augmentation is crucial in training deep models, preventing them from overfitting to limited data. Recent advances in generative AI, e.g., diffusion models, have enabled more sophisticated augmentation techniques that produce data…

Computer Vision and Pattern Recognition · Computer Science 2024-11-08 Soroush Abbasi Koohpayegani , Anuj Singh , K L Navaneet , Hamed Pirsiavash , Hadi Jamali-Rad

A ubiquitous challenge in machine learning is the problem of domain generalisation. This can exacerbate bias against groups or labels that are underrepresented in the datasets used for model development. Model bias can lead to unintended…

Deep generative models are effective methods of modeling data. However, it is not easy for a single generative model to faithfully capture the distributions of complex data such as images. In this paper, we propose an approach for boosting…

Machine Learning · Computer Science 2019-05-14 Fan Bao , Hang Su , Jun Zhu

Text-to-Image (TTI) generative models have shown great progress in the past few years in terms of their ability to generate complex and high-quality imagery. At the same time, these models have been shown to suffer from harmful biases,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Aditya Chinchure , Pushkar Shukla , Gaurav Bhatt , Kiri Salij , Kartik Hosanagar , Leonid Sigal , Matthew Turk

We propose a novel approach for using unsupervised boosting to create an ensemble of generative models, where models are trained in sequence to correct earlier mistakes. Our meta-algorithmic framework can leverage any existing base learner…

Machine Learning · Computer Science 2017-12-25 Aditya Grover , Stefano Ermon

Data scarcity in medical imaging poses significant challenges due to privacy concerns. Diffusion models, a recent generative modeling technique, offer a potential solution by generating synthetic and realistic data. However, questions…

Image and Video Processing · Electrical Eng. & Systems 2024-12-24 Abdullah al Nomaan Nafi , Md. Alamgir Hossain , Rakib Hossain Rifat , Md Mahabub Uz Zaman , Md Manjurul Ahsan , Shivakumar Raman

Deep learning models for skin disease classification require large, diverse, and well-annotated datasets. However, such resources are often limited due to privacy concerns, high annotation costs, and insufficient demographic representation.…

Image and Video Processing · Electrical Eng. & Systems 2025-08-01 Jamil Fayyad , Nourhan Bayasi , Ziyang Yu , Homayoun Najjaran

Annotated images and ground truth for the diagnosis of rare and novel diseases are scarce. This is expected to prevail, considering the small number of affected patient population and limited clinical expertise to annotate images. Further,…

Computer Vision and Pattern Recognition · Computer Science 2022-11-01 Karthik Desingu , Mirunalini P. , Aravindan Chandrabose

Recent advances in generative medical models are constrained by modality-specific scenarios that hinder the integration of complementary evidence from imaging, pathology, and clinical notes. This fragmentation limits their evolution into…

Computer Vision and Pattern Recognition · Computer Science 2025-10-08 Jiawei Mao , Yuhan Wang , Lifeng Chen , Can Zhao , Yucheng Tang , Dong Yang , Liangqiong Qu , Daguang Xu , Yuyin Zhou

Medical image segmentation models struggle with rare abnormalities due to scarce annotated pathological data. We propose DiffAug a novel framework that combines textguided diffusion-based generation with automatic segmentation validation to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Maham Nazir , Muhammad Aqeel , Francesco Setti