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Several combinatorial optimization problems can be solved with NISQ devices once that a corresponding quadratic unconstrained binary optimization (QUBO) form is derived. The aim of this work is to drastically reduce the variables needed for…

Quantum Physics · Physics 2026-02-25 Dario De Santis , Salvatore Tirone , Stefano Marmi , Vittorio Giovannetti

We report a quantum-classical hybrid scheme for factorization of bi-prime numbers (which are odd and square-free) using IBM's quantum processors. The hybrid scheme proposed here involves both classical optimization techniques and adiabatic…

Quantum Physics · Physics 2022-06-07 Ashwin Saxena , Abhishek Shukla , Anirban Pathak

In this paper, we study the problem of digital pre/post-coding design in multiple-input multiple-output (MIMO) systems with 1-bit resolution per complex dimension. The optimal solution that maximizes the received signal-to-noise ratio…

Signal Processing · Electrical Eng. & Systems 2024-06-10 Ioannis Krikidis

We demonstrate experimentally that the bias-field digitized counterdiabatic quantum optimization (BF-DCQO) algorithm on IBM's 156-qubit devices can outperform simulated annealing (SA) and CPLEX in time-to-approximate solutions for specific…

Combinatorial optimization problems are typically formulated using Quadratic Unconstrained Binary Optimization (QUBO), where constraints are enforced through penalty terms that introduce auxiliary variables and rapidly increase Hamiltonian…

Quantum Physics · Physics 2026-02-10 Shashank Sanjay Bhat , Peiyong Wang , Joseph West , Udaya Parampalli

In finance, assessing the creditworthiness of loan applicants requires lenders to cluster borrowers using rating scales. Financial institutions must define the scales in compliance with strict institutional constraints, resulting in solving…

Accurate prediction of mRNA secondary structure is critical for understanding gene expression, translation efficiency, and advancing mRNA-based therapeutics. However, the combinatorial complexity of possible foldings, especially in long…

We propose and compare Constraint Programming (CP) and Quantum Annealing (QA) approaches for rolling stock assignment optimisation considering necessary maintenance tasks. In the CP approach, we model the problem with an Alldifferent…

Artificial Intelligence · Computer Science 2023-09-26 Patricia Bickert , Cristian Grozea , Ronny Hans , Matthias Koch , Christina Riehn , Armin Wolf

We propose a prime factoring machine operated in a frame work of quantum annealing (QA). The idea is inverse operation of a quantum-mechanically reversible multiplier implemented with QA-based Boolean logic circuits. We designed the QA…

Quantum Physics · Physics 2017-12-19 M. Maezawa , K. Imafuku , M. Hidaka , H. Koike , S. Kawabata

In black-box combinatorial optimization, objective evaluations are often expensive, so high quality solutions must be found under a limited budget. Factorization machine with quantum annealing (FMQA) builds a quadratic surrogate model from…

Machine Learning · Computer Science 2026-02-11 Tetsuro Abe , Masashi Yamashita , Shu Tanaka

Quantum annealing technologies aim to solve computational optimization and sampling problems. QPU (Quantum Processing Unit) machines such as the D-Wave system use the QUBO (Quadratic Unconstrained Binary Optimization) formula to define…

Quantum Physics · Physics 2022-03-28 Toufan D. Tambunan , Andriyan B. Suksmono , Ian J. M. Edward , Rahmat Mulyawan

The quadratic unconstrained binary optimization (QUBO) problem arises in diverse optimization applications ranging from Ising spin problems to classical problems in graph theory and binary discrete optimization. The use of preprocessing to…

Artificial Intelligence · Computer Science 2017-05-29 Fred Glover , Mark Lewis , Gary Kochenberger

Factoring large integers using a quantum computer is an outstanding research problem that can illustrate true quantum advantage over classical computers. Exponential time order is required in order to find the prime factors of an integer by…

Quantum Physics · Physics 2018-07-13 Avinash Dash , Deepankar Sarmah , Bikash K. Behera , Prasanta K. Panigrahi

Solving combinatorial optimization problems of the kind that can be codified by quadratic unconstrained binary optimization (QUBO) is a promising application of quantum computation. Some problems of this class suitable for practical…

Shor's algorithm has seriously challenged information security based on public key cryptosystems. However, to break the widely used RSA-2048 scheme, one needs millions of physical qubits, which is far beyond current technical capabilities.…

This paper addresses the Quadratic Multiple Constraints Variable-Sized Bin Packing Problem (QMC-VSBPP), a challenging combinatorial optimization problem that generalizes the classical bin packing problem by incorporating multiple capacity…

Neural and Evolutionary Computing · Computer Science 2026-03-27 Natalia A. Santos , Marlon Jeske , Antonio A. Chaves

Factorization machine with quadratic-optimization annealing (FMQA) is a black-box optimization method that combines a factorization machine (FM) surrogate with QUBO-based search by an Ising machine. When FMQA is applied to integer or…

Machine Learning · Computer Science 2026-05-07 Taiga Hayashi , Yuya Seki , Kotaro Terada , Yosuke Mukasa , Shuta Kikuchi , Shu Tanaka

Real-world optimization problems must undergo a series of transformations before becoming solvable on current quantum hardware. Even for a fixed problem, the number of possible transformation paths -- from industry-relevant formulations…

Quantum computing and modern tensor-based computing have a strong connection, which is especially demonstrated by simulating quantum computations with tensor networks. The other direction is less studied: quantum computing is not often…

Quantum Physics · Physics 2025-09-03 Valter Uotila

Ising machines, including quantum annealing machines, are promising next-generation computers for combinatorial optimization problems. However, due to hardware limitations, most Ising-type hardware can only solve objective functions…

Statistical Mechanics · Physics 2025-10-29 Kazuki Ikeuchi , Yoshiki Matsuda , Shu Tanaka
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