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Given the limitations on the number of qubits in current noisy intermediate-scale quantum (NISQ) devices, the implementation of large-scale quantum algorithms on such devices is challenging, prompting research into distributed quantum…

Quantum Physics · Physics 2025-03-04 Xinyu Chen , Zilu Chen , Pengcheng Zhu , Xueyun Cheng , Zhijin Guan

Diagnosing the minimal set of faults capable of explaining a set of given observations, e.g., from sensor readouts, is a hard combinatorial optimization problem usually tackled with artificial intelligence techniques. We present the mapping…

Quantum annealers provide an effective framework for solving large-scale combinatorial optimization problems. This work presents a novel methodology for training Variational Quantum Algorithms (VQAs) by reformulating the parameter…

Quantum Physics · Physics 2025-09-03 Ernesto Acosta , Guillermo Botella , Carlos Cano

Quadratic unconstrained binary optimization (QUBO) provides problem formulations for various computational problems that can be solved with dedicated QUBO solvers, which can be based on classical or quantum computation. A common approach to…

Annealing machines specialized for combinatorial optimization problems have been developed, and some companies offer services to use those machines. Such specialized machines can only handle binary variables, and their input format is the…

Quantum Physics · Physics 2023-03-24 Yuki Furue , Makiko Konoshima , Hirotaka Tamura , Jun Ohkubo

The RNA inverse folding problem aims to identify nucleotide sequences that preferentially adopt a given target secondary structure. While various heuristic and machine learning-based approaches have been proposed, many require a large…

Machine Learning · Computer Science 2026-02-19 Shuta Kikuchi , Shu Tanaka

We propose and implement a family of quantum-informed recursive optimization (QIRO) algorithms for combinatorial optimization problems. Our approach leverages quantum resources to obtain information that is used in problem-specific…

Quantum Annealing (QA) and QAOA are promising quantum optimisation algorithms used for finding approximate solutions to combinatorial problems on near-term NISQ systems. Many NP-hard problems can be reformulated as Quadratic Unconstrained…

Quantum Physics · Physics 2025-10-06 Namasi G Sankar , Georgios Miliotis , Simon Caton

Clustering is a powerful machine learning technique that groups "similar" data points based on their characteristics. Many clustering algorithms work by approximating the minimization of an objective function, namely the sum of…

Quantum Physics · Physics 2018-01-29 Vaibhaw Kumar , Gideon Bass , Casey Tomlin , Joseph Dulny

We present an algorithm for quantum-assisted cluster analysis (QACA) that makes use of the topological properties of a D-Wave 2000Q quantum processing unit (QPU). Clustering is a form of unsupervised machine learning, where instances are…

Quantum Physics · Physics 2018-03-09 Florian Neukart , David Von Dollen , Christian Seidel

We factorize a 48-bit integer using 10 trapped-ion qubits on a Quantinuum's quantum computer. This result outperforms the recent achievement by B. Yan et al., arXiv:2212.12372 (2022), increasing the success probability by a factor of 6 with…

Quantum Physics · Physics 2023-01-27 Narendra N. Hegade , Enrique Solano

Quantum computing devices are believed to be powerful in solving the prime factorization problem, which is at the heart of widely deployed public-key cryptographic tools. However, the implementation of Shor's quantum factorization algorithm…

We present a quantum feature-selection framework based on a higher-order unconstrained binary optimization (HUBO) formulation that explicitly incorporates multivariate dependencies beyond standard quadratic encodings. In contrast to…

The advent of quantum computing processors with possibility to scale beyond experimental capacities magnifies the importance of studying their applications. Combinatorial optimization problems can be one of the promising applications of…

Quantum Physics · Physics 2017-08-18 Ehsan Zahedinejad , Arman Zaribafiyan

The reconstruction of charged particles will be a key computing challenge for the high-luminosity Large Hadron Collider (HL-LHC) where increased data rates lead to large increases in running time for current pattern recognition algorithms.…

Quantum Physics · Physics 2019-02-25 Frederic Bapst , Wahid Bhimji , Paolo Calafiura , Heather Gray , Wim Lavrijsen , Lucy Linder

The Quadratic Unconstrained Binary Optimization (QUBO) model has gained prominence in recent years with the discovery that it unifies a rich variety of combinatorial optimization problems. By its association with the Ising problem in…

Data Structures and Algorithms · Computer Science 2019-11-06 Fred Glover , Gary Kochenberger , Yu Du

Quantum integer factorization is a potential quantum computing solution that may revolutionize cryptography. Nevertheless, a scalable and efficient quantum algorithm for noisy intermediate-scale quantum computers looks far-fetched. We…

This study proposes a novel method for simplifying inequality constraints in Higher-Order Binary Optimization (HOBO) formulations. The proposed method addresses challenges associated with Quadratic Unconstrained Binary Optimization (QUBO)…

Optimization and Control · Mathematics 2025-01-22 Yuichiro Minato

Combinatorial optimization plays a crucial role in many industrial applications. While classical computing often struggles with complex instances, quantum optimization emerges as a promising alternative. Here, we present an enhanced…

Quantum Approximate Optimization Algorithm (QAOA) can be used to solve quadratic unconstrained binary optimization (QUBO) problems. However, the size of the solvable problem is limited by the number of qubits. To leverage noisy…

Quantum Physics · Physics 2025-06-10 Wending Zhao , Gaoxiang Tang