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Microelectronic morphogenesis is the creation and maintenance of complex functional structures by microelectronic information within shape-changing materials. Only recently has in-built information technology begun to be used to reshape…
I propose here a new concept of information based on two relevant aspects of its expression. The first related to the undeniable fact that the expression of information modifies the physical state of its receiver. The second to the…
The plethora of single-cell multi-omics data is getting treatment with deep learning, a revolutionary method in artificial intelligence, which has been increasingly expanding its reign over the bioscience frontiers.
Changes in a cell's external or internal conditions are usually reflected in the concentrations of the relevant transcription factors. These proteins in turn modulate the expression levels of the genes under their control and sometimes need…
Electrons and photons offer complementary strengths for information processing. Photons are excellent for communication, while electrons are superior for computation and memory. Cognition requires distributed computation to be communicated…
If life is sustained by a process of photosynthesis, not necessarily the same existing on Earth, the surface temperature of the star and the orbit of the host planet cannot be whatsoever. In fact the global life cycle, no matter how…
A striking difference between brain-inspired neuromorphic processors and current von Neumann processors architectures is the way in which memory and processing is organized. As Information and Communication Technologies continue to address…
We need much better understanding of information processing and computation as its primary form. Future progress of new computational devices capable of dealing with problems of big data, internet of things, semantic web, cognitive robotics…
Cells receive signaling molecules by receptors and relay information via sensory networks so that they can respond properly depending on the type of signal. Recent studies have shown that cells can extract multi-dimensional information from…
We develop a quantum information protocol that models the biological behaviors of individuals living in a natural selection scenario. The artificially engineered evolution of the quantum living units shows the fundamental features of life…
Ions in water are important in biology, from molecules to organs. Classically, ions in water are treated as ideal noninteracting particles in a perfect gas. Excess free energy of ion was zero. Mathematics was not available to deal…
The productivity of a planetary biosphere is limited by how its free-energy budget is partitioned between maintaining a habitable environment, driving metabolism, and processing heritable information. We derive an upper bound on net primary…
The functional computation of the human brain arises from the collective behaviour of the underlying neural network. The emerging technology enables the recording of population activity in neurons, and the theory of neural networks is…
Active inference is a process theory of the brain that states that all living organisms infer actions in order to minimize their (expected) free energy. However, current experiments are limited to predefined, often discrete, state spaces.…
The paper explores an approach to constructing energy landscapes of a formal neuron and multilayer artificial neural networks (ANNs). Their analysis makes it possible to determine the conceptual limitations of both classification ANNs…
Darwinian evolution tends to produce energy-efficient outcomes. On the other hand, energy limits computation, be it neural and probabilistic or digital and logical. Taking a particular energy-efficient viewpoint, we define neural…
The biological cell exhibits a fantastic range of behaviors, but ultimately these are governed by a handful of physical and chemical principles. Here we explore simple theory, known for decades and based on the simple thermodynamics of…
In a post-industrial society, the workplace is dominated primarily by Knowledge Work, which is achieved mostly through human cognitive processing, such as analysis, comprehension, evaluation, and decision-making. Many of these processes…
Intelligent behavior in life-like systems often arises from the ability to gather, process, and act on information. While active matter provides a framework for studying life-like dynamics, it typically omits internal information-processing…
Life relies on a sophisticated metabolic molecular machinery that turns over high-energy molecules to evolve complex macromolecules and assemblies. At the molecular origin of life, such machinery was absent, implying the need for simple yet…