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Living cells encode and transmit information in the temporal dynamics of biochemical components. Gaining a detailed understanding of the input-output relationship in biological systems therefore requires quantitative measures that capture…

Molecular Networks · Quantitative Biology 2019-04-04 Lorenzo Duso , Christoph Zechner

We develop numerical and analytical approaches to calculate mutual information between complete paths of two molecular components embedded into a larger reaction network. In particular, we focus on a continuous-time Markov chain formalism,…

Molecular Networks · Quantitative Biology 2022-08-09 Anne-Lena Moor , Christoph Zechner

Microorganisms employ sophisticated mechanisms for intercellular communication and environmental sensing, with quorum sensing serving as a fundamental regulatory process. Dysregulation of quorum sensing has been implicated in various…

Emerging Technologies · Computer Science 2025-09-30 O. Tansel Baydas , Efe Yatgin , Ozgur B. Akan

We consider the information fiber optical channel modeled by the nonlinear Schrodinger equation with additive Gaussian noise. Using path-integral approach and perturbation theory for the small dimensionless parameter of the second…

Information Theory · Computer Science 2023-08-03 A. V. Reznichenko , V. O. Guba

Cells must continuously sense and respond to time-varying environmental stimuli. These signals are transmitted and processed by biochemical signalling networks. However, the biochemical reactions making up these networks are intrinsically…

Molecular Networks · Quantitative Biology 2015-05-18 Filipe Tostevin , Pieter Rein ten Wolde

Efficient information processing is crucial for both living organisms and engineered systems. The mutual information rate, a core concept of information theory, quantifies the amount of information shared between the trajectories of input…

Molecular Networks · Quantitative Biology 2025-09-01 Manuel Reinhardt , Age J. Tjalma , Anne-Lena Moor , Christoph Zechner , Pieter Rein ten Wolde

Cells are often considered input-output devices that maximize the transmission of information by converting extracellular stimuli (input) via signaling pathways (communication channel) to cell behavior (output). However, in biological…

Cell Behavior · Quantitative Biology 2019-11-04 Gabriele Micali , Robert G. Endres

Quantitatively predictive models of biomolecular circuits are important tools for the design of synthetic biology and molecular communication circuits. The information content of typical time-lapse single-cell data for the inference of…

Molecular Networks · Quantitative Biology 2021-01-11 Tim Prangemeier , Christian Wildner , Maleen Hanst , Heinz Koeppl

The information flow in a quantum system is a fundamental feature of its dynamics. An important class of dynamics are quantum cellular automata (QCA), systems with discrete updates invariant in time and space, for which an index theory has…

Quantum Physics · Physics 2024-02-02 Elisabeth Wagner , Ramil Nigmatullin , Alexei Gilchrist , Gavin K. Brennen

Identifying the origin of nonequilibrium characteristics in a generic interacting system having multiple degrees of freedom is a challenging task. In this context, information theoretic measures such as mutual information and related…

Statistical Mechanics · Physics 2025-07-24 Biswajit Das , Sreekanth K Manikandan , Ayan Banerjee

Mutual information is a widely-used information theoretic measure to quantify the amount of association between variables. It is used extensively in many applications such as image registration, diagnosis of failures in electrical machines,…

Computation · Statistics 2021-08-21 Luai Al-Labadi , Forough Fazeli-Asl , Zahra Saberi

In this paper, it is shown that the rank function of a matroid can be represented by a "mutual information function" if and only if the matroid is binary. The mutual information function considered is the one measuring the amount of…

Information Theory · Computer Science 2010-12-22 Emmanuel Abbe

Pinning down a precise understanding of information flow within physical interactions remains a central concern to fields like stochastic thermodynamics and quantum information science. In both spheres a careful accounting of bits (or…

Statistical Mechanics · Physics 2026-01-15 Miles Miller-Dickson , Christopher Rose

Information delivery via molecular signals is abundant in nature and potentially useful for industry sensing. Many propagation channels (e.g., tissue membranes and catalyst beds) contain porous medium materials and the impact this has on…

Information Theory · Computer Science 2020-04-24 Yuting Fang , Weisi Guo , Matteo Icardi , Adam Noel , Nan Yang

A framework for a quantum information theory is introduced that is based on the measure of quantum information associated with probability distribution predicted by quantum measuring of state. The entanglement between states of measured…

Quantum Physics · Physics 2007-05-23 Yi-Xin Chen

This paper compares and evaluates a set of non-parametric mutual information estimators with the goal of providing a novel toolset to progress in the analysis of the capacity of the nonlinear optical channel, which is currently an open…

Information Theory · Computer Science 2018-01-25 Tommaso Catuogno , Menelaos Ralli Camara , Marco Secondini

Biochemical networks can respond to temporal characteristics of time-varying signals. To understand how reliably biochemical networks can transmit information we must consider how an input signal as a function of time--the input…

Molecular Networks · Quantitative Biology 2015-05-13 Filipe Tostevin , Pieter Rein ten Wolde

Cells sense environmental signals and transmit information intracellularly through changes in the abundance of molecular components. Such molecular abundances can be measured in single cells and exhibit significant heterogeneity in clonal…

Quantitative Methods · Quantitative Biology 2024-09-27 Raymond Fan , Andreas Hilfinger

Data from spectrophotometers form vectors of a large number of exploitable variables. Building quantitative models using these variables most often requires using a smaller set of variables than the initial one. Indeed, a too large number…

Machine Learning · Computer Science 2007-09-26 Fabrice Rossi , Amaury Lendasse , Damien François , Vincent Wertz , Michel Verleysen

The asymptotic mutual information (MI) analysis for multiple-input multiple-output (MIMO) systems over double-scattering channels has achieved engaging results, but the convergence rates of the mean, variance, and the distribution of the MI…

Information Theory · Computer Science 2023-01-18 Xin Zhang , Shenghui Song
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