Microorganisms employ sophisticated mechanisms for intercellular communication and environmental sensing, with quorum sensing serving as a fundamental regulatory process. Dysregulation of quorum sensing has been implicated in various diseases. While most theoretical studies focus on mathematical modeling of quorum sensing dynamics, the communication-theoretic aspects remain less explored. In this study, we investigate the information processing capabilities of quorum sensing systems using a stochastic differential equation framework that links intracellular gene regulation to extracellular autoinducer dynamics. We quantify mutual information as a measure of signaling efficiency and information fidelity in two major bacterial phyla of the gut microbiota: Firmicutes and Bacteroidetes.
@article{arxiv.2509.25057,
title = {Information Transmission in Quorum Sensing for Gut Microbiome},
author = {O. Tansel Baydas and Efe Yatgin and Ozgur B. Akan},
journal= {arXiv preprint arXiv:2509.25057},
year = {2025}
}