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Quantitative Structure-Activity Relationship (QSAR) modeling is key in drug discovery, but classical methods face limitations when handling high-dimensional data and capturing complex molecular interactions. This research proposes enhancing…

Quantum Physics · Physics 2025-07-09 Alejandro Giraldo , Daniel Ruiz , Mariano Caruso , Guido Bellomo

Qualitative structure-activity relationship (QSAR) is important for drug discovery and offers valuable insights into the biological interactions of potential drug candidates. It has been demonstrated that QSAR can be accurately predicted by…

Quantum Physics · Physics 2025-01-24 Wei-Yin Chiang , Po-Yu Kao , Tzu-Lan Yeh , Ya-Chu Yang , Yen-Chu Lin , Alex Zhavoronkov

Quantum computing combined with machine learning (ML) is a highly promising research area, with numerous studies demonstrating that quantum machine learning (QML) is expected to solve scientific problems more effectively than classical ML.…

Quantum Physics · Physics 2025-07-18 Liang Zhang , Yin Xu , Mohan Wu , Liang Wang , Hua Xu

Quantitative structure-activity relationship (QSAR) is a computer modeling technique for identifying relationships between the structural properties of chemical compounds and biological activity. QSAR modeling is necessary for drug…

Machine Learning · Computer Science 2024-06-19 Rifkat Davronova , Fatima Adilovab

As quantum computers become increasingly practical, so does the prospect of using quantum computation to improve upon traditional algorithms. Kernel methods in machine learning is one area where such improvements could be realized in the…

Quantum Physics · Physics 2023-05-30 Ara Ghukasyan , Jack S. Baker , Oktay Goktas , Juan Carrasquilla , Santosh Kumar Radha

The meeting of artificial intelligence (AI) and quantum computing is already a reality; quantum machine learning (QML) promises the design of better regression models. In this work, we extend our previous studies of materials discovery…

Machine Learning (ML) for Ligand Based Virtual Screening (LB-VS) is an important in-silico tool for discovering new drugs in a faster and cost-effective manner, especially for emerging diseases such as COVID-19. In this paper, we propose a…

We investigate the learning of quantitative structure activity relationships (QSARs) as a case-study of meta-learning. This application area is of the highest societal importance, as it is a key step in the development of new medicines. The…

Artificial Intelligence · Computer Science 2017-09-13 Ivan Olier , Noureddin Sadawi , G. Richard Bickerton , Joaquin Vanschoren , Crina Grosan , Larisa Soldatova , Ross D. King

Identifying molecular properties, including side effects, is a critical yet time-consuming step in drug development. Failing to detect these side effects before regulatory submission can result in significant financial losses and production…

Machine Learning · Computer Science 2025-04-30 Collin Beaudoin , Swaroop Ghosh

Recently deep learning based quantitative structure-activity relationship (QSAR) models has shown surpassing performance than traditional methods for property prediction tasks in drug discovery. However, most DL based QSAR models are…

Biomolecules · Quantitative Biology 2023-04-25 Zhifeng Gao , Xiaohong Ji , Guojiang Zhao , Hongshuai Wang , Hang Zheng , Guolin Ke , Linfeng Zhang

Machine learning has been increasingly utilized in the field of biomedical research to accelerate the drug discovery process. In recent years, the emergence of quantum computing has been followed by extensive exploration of quantum machine…

In molecular research, the modelling and analysis of molecules through simulation is an important part that has a direct influence on medical development, material science and drug discovery. The processing power required to design protein…

Quantum Physics · Physics 2026-03-24 Prateek Jain , Param Pathak , Krishna Bhatia , Shalini Devendrababu , Srinjoy Ganguly

Classical machine learning, extensively utilized across diverse domains, faces limitations in speed, efficiency, parallelism, and processing of complex datasets. In contrast, quantum machine learning algorithms offer significant advantages,…

Quantum Physics · Physics 2024-06-05 Anand Babu , Saurabh G. Ghatnekar , Amit Saxena , Dipankar Mandal

We propose a quantum kernel learning (QKL) framework to address the inherent data sparsity issues often encountered in training large-scare acoustic models in low-resource scenarios. We project acoustic features based on…

Kernel methods play an important role in machine learning applications due to their conceptual simplicity and superior performance on numerous machine learning tasks. Expressivity of a machine learning model, referring to the ability of the…

Financial services is a prospect industry where unlocked near-term quantum utility could yield profitable potential, and, in particular, quantum machine learning algorithms could potentially benefit businesses by improving the quality of…

Quantum Machine Learning (QML) shows how it maintains certain significant advantages over machine learning methods. It now shows that hybrid quantum methods have great scope for deployment and optimisation, and hold promise for future…

Machine Learning · Computer Science 2023-01-03 Juan Kenyhy Hancco-Quispe , Jordan Piero Borda-Colque , Fred Torres-Cruz

Quantum Machine Learning (QML) continues to evolve, unlocking new opportunities for diverse applications. In this study, we investigate and evaluate the applicability of QML models for binary classification of genome sequence data by…

Machine Learning · Computer Science 2025-01-15 Navneet Singh , Shiva Raj Pokhrel

Quantum algorithms based on quantum kernel methods have been investigated previously [1]. A quantum advantage is derived from the fact that it is possible to construct a family of datasets for which, only quantum processing can recognise…

Quantum Physics · Physics 2024-05-08 Sanjeev Naguleswaran

Quantum machine learning (QML) has witnessed immense progress recently, with quantum support vector machines (QSVMs) emerging as a promising model. This paper focuses on the two existing QSVM methods: quantum kernel SVM (QK-SVM) and quantum…

Quantum Physics · Physics 2024-02-02 Nouhaila Innan , Muhammad Al-Zafar Khan , Biswaranjan Panda , Mohamed Bennai
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