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The field of drug discovery hinges on the accurate prediction of binding affinity between prospective drug molecules and target proteins, especially when such proteins directly influence disease progression. However, estimating binding…

Quantum-enhanced machine learning is a rapidly evolving field that aims to leverage the unique properties of quantum mechanics to enhance classical machine learning. However, the practical applicability of these methods remains an open…

Quantum Physics · Physics 2025-02-18 Diego Alvarez-Estevez

This study explores the performance of Quantum Support Vector Classifiers (QSVCs) and Quantum Neural Networks (QNNs) in comparison to classical models for machine learning tasks. By evaluating these models on the Iris and MNIST-PCA…

Quantum Physics · Physics 2025-12-04 Tomás Villalba-Ferreiro , Eduardo Mosqueira-Rey , Diego Alvarez-Estevez

The importance of analyzing nontrivial datasets when testing quantum machine learning (QML) models is becoming increasingly prominent in literature, yet a cohesive framework for understanding dataset characteristics remains elusive. In this…

Quantum Physics · Physics 2025-08-28 Alona Sakhnenko , Christian B. Mendl , Jeanette M. Lorenz

This work endeavors to juxtapose the efficacy of machine learning algorithms within classical and quantum computational paradigms. Particularly, by emphasizing on Support Vector Machines (SVM), we scrutinize the classification prowess of…

Machine Learning · Computer Science 2023-10-18 Davut Emre Tasar , Kutan Koruyan , Ceren Ocal Tasar

Machine learning and quantum computing are being progressively explored to shed light on possible computational approaches to deal with hitherto unsolvable problems. Classical methods for machine learning are ubiquitous in pattern…

Quantum Physics · Physics 2024-07-10 Papri Saha

Quantum machine learning (QML) investigates how quantum phenomena can be exploited in order to learn data in an alternative way, \textit{e.g.} by means of a quantum computer. While recent results evidence that QML models can potentially…

Quantum Physics · Physics 2024-07-10 Y. Cordero , S. Biswas , F. Vilariño , M. Bilkis

The application of quantum computation to accelerate machine learning algorithms is one of the most promising areas of research in quantum algorithms. In this paper, we explore the power of quantum learning algorithms in solving an…

Quantum Physics · Physics 2023-04-19 Yusen Wu , Bujiao Wu , Jingbo Wang , Xiao Yuan

In this paper, we explore the potential of quantum computing in enhancing malware detection through the application of Quantum Machine Learning (QML). Our main objective is to investigate the performance of the Quantum Support Vector…

Quantum Physics · Physics 2025-10-09 Eliška Krátká , Aurél Gábor Gábris

Hybrid quantum-classical machine learning offers a path to leverage noisy intermediate-scale quantum (NISQ) devices for drug discovery, but optimal model architectures remain unclear. We systematically optimize the quantum-classical bridge…

Machine Learning · Computer Science 2025-07-28 Andrew Smith , Erhan Guven

Quantum machine learning is considered one of the current research fields with immense potential. In recent years, Havl\'i\v{c}ek et al. [Nature 567, 209-212 (2019)] have proposed a quantum machine learning algorithm with quantum-enhanced…

Quantum Physics · Physics 2025-06-09 Chao Ding , Shi Wang , Yaonan Wang , Weibo Gao

Machine learning and quantum computing are two technologies that are causing a paradigm shift in the performance and behavior of certain algorithms, achieving previously unattainable results. Machine learning (kernel classification) has…

Quantum Physics · Physics 2020-04-28 Siddharth Sharma

The functional characterization of different neuronal types has been a longstanding and crucial challenge. With the advent of physical quantum computers, it has become possible to apply quantum machine learning algorithms to translate…

Quantum Physics · Physics 2025-02-11 Xavier Vasques , Hanhee Paik , Laura Cif

In drug discovery, in vitro and in vivo experiments reveal biochemical activities related to the efficacy and toxicity of compounds. The experimental data accumulate into massive, ever-evolving, and sparse datasets. Quantitative…

Machine Learning · Computer Science 2024-05-21 Bingjia Yang , Yunsie Chung , Archer Y. Yang , Bo Yuan , Xiang Yu

Quantum machine learning (QML) has emerged as an important area for Quantum applications, although useful QML applications would require many qubits. Therefore our paper is aimed at exploring the successful application of the Quantum…

Quantum Physics · Physics 2020-12-15 Jae-Eun Park , Brian Quanz , Steve Wood , Heather Higgins , Ray Harishankar

Quantum Machine Learning (QML) is considered one of the most promising applications of Quantum Computing in the Noisy Intermediate Scale Quantum (NISQ) era for the impact it is thought to have in the near future. Although promising…

Quantum Physics · Physics 2025-08-22 Valeria Repetto , Elia Giuseppe Ceroni , Giuseppe Buonaiuto , Romina D'Aurizio

Although recent advances in quantum machine learning (QML) offer significant potential for enhancing generative models, particularly in molecular design, a large array of classical approaches still face challenges in achieving high fidelity…

Machine Learning · Computer Science 2025-08-29 Afrar Jahin , Yi Pan , Yingfeng Wang , Tianming Liu , Wei Zhang

Quantum kernel methods (QKMs) have emerged as a prominent framework for supervised quantum machine learning. Unlike variational quantum algorithms, which rely on gradient-based optimisation and may suffer from issues such as barren…

Quantum Physics · Physics 2026-04-10 John Tanner , Chon-Fai Kam , Jingbo Wang

Quantum Kernels are projected to provide early-stage usefulness for quantum machine learning. However, highly sophisticated classical models are hard to surpass without losing interpretability, particularly when vast datasets can be…

Risk Management · Quantitative Finance 2024-04-04 Javier Mancilla , André Sequeira , Tomas Tagliani , Francisco Llaneza , Claudio Beiza

Quantum machine learning (QML) is rapidly transitioning from theoretical promise to practical relevance across data-intensive scientific domains. In this Review, we provide a structured overview of recent advances that bridge foundational…

Quantum Physics · Physics 2026-02-25 Vinit Singh , Amandeep Singh Bhatia , Mandeep Kaur Saggi , Manas Sajjan , Sabre Kais