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Latent space-based facial attribute editing methods have gained popularity in applications such as digital entertainment, virtual avatar creation, and human-computer interaction systems due to their potential for efficient and flexible…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Bo Liu , Xuan Cui , Run Zeng , Wei Duan , Chongwen Liu , Jinrui Qian , Lianggui Tang , Hongping Gan

The deep learning revolution has strongly impacted low-level image processing tasks such as style/domain transfer, enhancement/restoration, and visual quality assessments. Despite often being treated separately, the aforementioned tasks…

Image and Video Processing · Electrical Eng. & Systems 2025-08-26 Abhinau K. Venkataramanan , Cosmin Stejerean , Ioannis Katsavounidis , Hassene Tmar , Alan C. Bovik

In the realm of image generation, creating customized images from visual prompt with additional textual instruction emerges as a promising endeavor. However, existing methods, both tuning-based and tuning-free, struggle with interpreting…

Computer Vision and Pattern Recognition · Computer Science 2024-10-29 Jing He , Haodong Li , Yongzhe Hu , Guibao Shen , Yingjie Cai , Weichao Qiu , Ying-Cong Chen

Ensuring fairness across demographic groups in medical diagnosis is essential for equitable healthcare, particularly under distribution shifts caused by variations in imaging equipment and clinical practice. Vision-language models (VLMs)…

Computer Vision and Pattern Recognition · Computer Science 2025-08-27 Yuexuan Xia , Benteng Ma , Jiang He , Zhiyong Wang , Qi Dou , Yong Xia

Understanding the dynamic nature of protein structures is essential for comprehending their biological functions. While significant progress has been made in predicting static folded structures, modeling protein motions on microsecond to…

Molecular property prediction constitutes a cornerstone of drug discovery and materials science, necessitating models capable of disentangling complex structure-property relationships across diverse molecular modalities. Existing approaches…

Machine Learning · Computer Science 2026-03-24 Long Xu , Junping Guo , Jianbo Zhao , Jianbo Lu , Yuzhong Peng

Representation learning and \emph{de novo} generation of proteins are pivotal computational biology tasks. Whilst natural language processing (NLP) techniques have proven highly effective for protein sequence modelling, structure modelling…

Quantitative Methods · Quantitative Biology 2025-01-08 Benoit Gaujac , Jérémie Donà , Liviu Copoiu , Timothy Atkinson , Thomas Pierrot , Thomas D. Barrett

Confounding bias is a crucial problem when applying machine learning to practice, especially in clinical practice. We consider the problem of learning representations independent to multiple biases. In literature, this is mostly solved by…

Computer Vision and Pattern Recognition · Computer Science 2021-06-30 Xianjing Liu , Bo Li , Esther Bron , Wiro Niessen , Eppo Wolvius , Gennady Roshchupkin

We propose an image-to-image translation framework for facial attribute editing with disentangled interpretable latent directions. Facial attribute editing task faces the challenges of targeted attribute editing with controllable strength…

Computer Vision and Pattern Recognition · Computer Science 2025-04-01 Yusuf Dalva , Hamza Pehlivan , Cansu Moran , Öykü Irmak Hatipoğlu , Ayşegül Dündar

Many real-world datasets can be divided into groups according to certain salient features (e.g. grouping images by subject, grouping text by font, etc.). Often, machine learning tasks require that these features be represented separately…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-02-16 Dan Andrei Iliescu , Aliaksei Mikhailiuk , Damon Wischik , Rafal Mantiuk

Large pretrained language models have transformed natural language processing, and their adaptation to protein sequences -- viewed as strings of amino acid characters -- has advanced protein analysis. However, the distinct properties of…

Other Quantitative Biology · Quantitative Biology 2025-10-14 Sheikh Azizul Hakim , Kowshic Roy , M Saifur Rahman

Targeting to understand the underlying explainable factors behind observations and modeling the conditional generation process on these factors, we connect disentangled representation learning to Diffusion Probabilistic Models (DPMs) to…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Tao Yang , Yuwang Wang , Yan Lv , Nanning Zheng

Proteins are shaped by gradual evolution under biophysical and functional constraints. Protein language models learn rich evolutionary constraints from large-scale sequences, and discrete diffusion-based protein language models~(\eg, DPLMs)…

Machine Learning · Computer Science 2026-05-14 Xinyou Wang , Liang Hong , Jiasheng Ye , Zaixiang Zheng , Yu Li , Shujian Huang , Quanquan Gu

Estimating individual-level treatment effect from observational data is a fundamental problem in causal inference and has attracted increasing attention in the fields of education, healthcare, and public policy.In this work, we concentrate…

Machine Learning · Computer Science 2025-07-10 Hui Meng , Keping Yang , Xuyu Peng , Bo Zheng

The popular frameworks for self-supervised learning of speech representations have largely focused on frame-level masked prediction of speech regions. While this has shown promising downstream task performance for speech recognition and…

Computation and Language · Computer Science 2025-07-22 Varun Krishna , Sriram Ganapathy

Recent advances in de novo protein binder design have enabled increasing experimental validation, yet reported in silico metrics remain difficult to interpret or compare across studies due to non-standardized evaluation protocols. We…

Quantitative Methods · Quantitative Biology 2026-05-25 Cong Liu , Milong Ren , Jiaqi Guan , Chengyue Gong , Jinyuan Sun , Xinshi Chen , Wenzhi Xiao

Text-driven image synthesis has made significant advancements with the development of diffusion models, transforming how visual content is generated from text prompts. Despite these advances, text-driven image editing, a key area in…

Computer Vision and Pattern Recognition · Computer Science 2025-05-06 Mingzhen Huang , Jialing Cai , Shan Jia , Vishnu Suresh Lokhande , Siwei Lyu

Text-driven multi-object image editing which aims to precisely modify multiple objects within an image based on text descriptions, has recently attracted considerable interest. Existing works primarily follow the localize-editing paradigm,…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Fengyi Fu , Mengqi Huang , Lei Zhang , Zhendong Mao

Deep learning has transformed protein design, enabling accurate structure prediction, sequence optimization, and de novo protein generation. Advances in single-chain protein structure prediction via AlphaFold2, RoseTTAFold, ESMFold, and…

Machine Learning · Computer Science 2025-02-27 Gregory W. Kyro , Tianyin Qiu , Victor S. Batista

Proteins are essential macromolecules defined by their amino acid sequences, which determine their three-dimensional structures and, consequently, their functions in all living organisms. Therefore, generative protein modeling necessitates…

Machine Learning · Computer Science 2024-10-18 Xinyou Wang , Zaixiang Zheng , Fei Ye , Dongyu Xue , Shujian Huang , Quanquan Gu
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