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Systematic identification of protein function is a key problem in current biology. Most traditional methods fail to identify functionally equivalent proteins if they lack similar sequences, structural data or extensive manual annotations.…

Genomics · Quantitative Biology 2016-03-08 Dan Ofer

Understanding research papers remains challenging for foundation models due to specialized scientific discourse and complex figures and tables, yet existing benchmarks offer limited fine-grained evaluation at scale. To address this gap, we…

Computation and Language · Computer Science 2026-05-01 Yelin Chen , Fanjin Zhang , Suping Sun , Yunhe Pang , Yuanchun Wang , Jian Song , Xiaoyan Li , Lei Hou , Shu Zhao , Jie Tang , Juanzi Li

Protein modeling is an increasingly popular area of machine learning research. Semi-supervised learning has emerged as an important paradigm in protein modeling due to the high cost of acquiring supervised protein labels, but the current…

Machine Learning · Computer Science 2019-06-20 Roshan Rao , Nicholas Bhattacharya , Neil Thomas , Yan Duan , Xi Chen , John Canny , Pieter Abbeel , Yun S. Song

The LLM Agent, equipped with a code interpreter, is capable of automatically solving real-world coding tasks, such as data analysis and image editing. However, existing benchmarks primarily focus on either simplistic tasks, such as…

Software Engineering · Computer Science 2024-08-06 Yaolun Zhang , Yinxu Pan , Yudong Wang , Jie Cai

The increasing adoption of data-driven decision-making in public health has established epidemic forecasting as a critical area of research. Recent advances in multivariate forecasting models better capture complex temporal dependencies…

Machine Learning · Computer Science 2026-05-13 Madhurima Panja , Danny D'Agostino , Huitao Li , Tanujit Chakraborty , Nan Liu

Large Language Models (LLMs) remain difficult to evaluate comprehensively, particularly for languages other than English, where high-quality data is often limited. Existing benchmarks and leaderboards are predominantly English-centric, with…

Reasoning is an essential capacity for large language models (LLMs) to address complex tasks, where the identification of process errors is vital for improving this ability. Recently, process-level reward models (PRMs) were proposed to…

Artificial Intelligence · Computer Science 2025-03-18 Zhaopan Xu , Pengfei Zhou , Jiaxin Ai , Wangbo Zhao , Kai Wang , Xiaojiang Peng , Wenqi Shao , Hongxun Yao , Kaipeng Zhang

The modeling of bio-molecular system across molecular scales remains a central challenge in scientific research. Large language models (LLMs) are increasingly applied to bio-molecular discovery, yet systematic evaluation across multi-scale…

Machine Learning · Computer Science 2026-04-07 Yaxin Xu , Yue Zhou , Tianyu Zhao , Fengwei An , Zhixiang Ren

The electrocardiogram (ECG) is a cost-effective, highly accessible and widely employed diagnostic tool. With the advent of Foundation Models (FMs), the field of AI-assisted ECG interpretation has begun to evolve, as they enable model reuse…

Artificial Intelligence · Computer Science 2026-01-30 Francesca Filice , Edoardo De Rose , Simone Bartucci , Francesco Calimeri , Simona Perri

Frontier model progress is often measured by academic benchmarks, which offer a limited view of performance in real-world professional contexts. Existing evaluations often fail to assess open-ended, economically consequential tasks in…

Large language models (LLMs) can often generate functionally correct code, but their ability to produce efficient implementations for performance-critical systems tasks remains limited. Existing code benchmarks mainly emphasize correctness…

Software Engineering · Computer Science 2026-05-18 Huihao Jing , Wenbin Hu , Haochen Shi , Hanyu Yang , Sirui Zhang , Shaojin Chen , Haoran Li , Yangqiu Song

Evaluating Large Language Models (LLMs) on repository-level feature implementation is a critical frontier in software engineering. However, establishing a benchmark that faithfully mirrors realistic development scenarios remains a…

Computation and Language · Computer Science 2026-02-19 Haorui Chen , Chengze Li , Jia Li

As Large Language Model (LLM) alignment evolves from simple completions to complex, highly sophisticated generation, Reward Models are increasingly shifting toward rubric-guided evaluation to mitigate surface-level biases. However, the…

Artificial Intelligence · Computer Science 2026-03-04 Qiyuan Zhang , Junyi Zhou , Yufei Wang , Fuyuan Lyu , Yidong Ming , Can Xu , Qingfeng Sun , Kai Zheng , Peng Kang , Xue Liu , Chen Ma

Rapid progress in aerodynamic shape optimization (ASO) has outpaced currently-available standardized evaluation frameworks. Fair comparison requires a unified benchmark spanning diverse shape classes, objective formulations, and…

Machine Learning · Computer Science 2026-05-21 Shaghayegh Fazliani , Krissh Chawla , Jack Guo , Yiren Shen , Matthias Ihme , Madeleine Udell

Recent developments in Japanese large language models (LLMs) primarily focus on general domains, with fewer advancements in Japanese biomedical LLMs. One obstacle is the absence of a comprehensive, large-scale benchmark for comparison.…

Computation and Language · Computer Science 2024-09-23 Junfeng Jiang , Jiahao Huang , Akiko Aizawa

Model merging provides a scalable alternative to multi-task training by combining specialized finetuned models through parameter arithmetic, enabling efficient deployment without the need for joint training or access to all task data. While…

Machine Learning · Computer Science 2025-10-21 Yifei He , Siqi Zeng , Yuzheng Hu , Rui Yang , Tong Zhang , Han Zhao

Mass spectrometry is the dominant technology in the field of proteomics, enabling high-throughput analysis of the protein content of complex biological samples. Due to the complexity of the instrumentation and resulting data, sophisticated…

Intellectual Property (IP) is a highly specialized domain that integrates technical and legal knowledge, making it inherently complex and knowledge-intensive. Recent advancements in LLMs have demonstrated their potential to handle…

Advancements in Multimodal Large Language Models (MLLMs) have significantly improved medical task performance, such as Visual Question Answering (VQA) and Report Generation (RG). However, the fairness of these models across diverse…

Computer Vision and Pattern Recognition · Computer Science 2024-10-03 Peiran Wu , Che Liu , Canyu Chen , Jun Li , Cosmin I. Bercea , Rossella Arcucci

Neuromorphic computing shows promise for advancing computing efficiency and capabilities of AI applications using brain-inspired principles. However, the neuromorphic research field currently lacks standardized benchmarks, making it…

Artificial Intelligence · Computer Science 2025-01-16 Jason Yik , Korneel Van den Berghe , Douwe den Blanken , Younes Bouhadjar , Maxime Fabre , Paul Hueber , Weijie Ke , Mina A Khoei , Denis Kleyko , Noah Pacik-Nelson , Alessandro Pierro , Philipp Stratmann , Pao-Sheng Vincent Sun , Guangzhi Tang , Shenqi Wang , Biyan Zhou , Soikat Hasan Ahmed , George Vathakkattil Joseph , Benedetto Leto , Aurora Micheli , Anurag Kumar Mishra , Gregor Lenz , Tao Sun , Zergham Ahmed , Mahmoud Akl , Brian Anderson , Andreas G. Andreou , Chiara Bartolozzi , Arindam Basu , Petrut Bogdan , Sander Bohte , Sonia Buckley , Gert Cauwenberghs , Elisabetta Chicca , Federico Corradi , Guido de Croon , Andreea Danielescu , Anurag Daram , Mike Davies , Yigit Demirag , Jason Eshraghian , Tobias Fischer , Jeremy Forest , Vittorio Fra , Steve Furber , P. Michael Furlong , William Gilpin , Aditya Gilra , Hector A. Gonzalez , Giacomo Indiveri , Siddharth Joshi , Vedant Karia , Lyes Khacef , James C. Knight , Laura Kriener , Rajkumar Kubendran , Dhireesha Kudithipudi , Shih-Chii Liu , Yao-Hong Liu , Haoyuan Ma , Rajit Manohar , Josep Maria Margarit-Taulé , Christian Mayr , Konstantinos Michmizos , Dylan R. Muir , Emre Neftci , Thomas Nowotny , Fabrizio Ottati , Ayca Ozcelikkale , Priyadarshini Panda , Jongkil Park , Melika Payvand , Christian Pehle , Mihai A. Petrovici , Christoph Posch , Alpha Renner , Yulia Sandamirskaya , Clemens JS Schaefer , André van Schaik , Johannes Schemmel , Samuel Schmidgall , Catherine Schuman , Jae-sun Seo , Sadique Sheik , Sumit Bam Shrestha , Manolis Sifalakis , Amos Sironi , Kenneth Stewart , Matthew Stewart , Terrence C. Stewart , Jonathan Timcheck , Nergis Tömen , Gianvito Urgese , Marian Verhelst , Craig M. Vineyard , Bernhard Vogginger , Amirreza Yousefzadeh , Fatima Tuz Zohora , Charlotte Frenkel , Vijay Janapa Reddi