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White matter hyperintensity (WMH) is commonly found in elder individuals and appears to be associated with brain diseases. U-net is a convolutional network that has been widely used for biomedical image segmentation. Recently, U-net has…

Computer Vision and Pattern Recognition · Computer Science 2018-07-30 Yue Zhang , Wanli Chen , Yifan Chen , Xiaoying Tang

Brain atrophy and white matter hyperintensity (WMH) are critical neuroimaging features for ascertaining brain injury in cerebrovascular disease and multiple sclerosis. Automated segmentation and quantification is desirable but existing…

Despite the undeniable progress in visual recognition tasks fueled by deep neural networks, there exists recent evidence showing that these models are poorly calibrated, resulting in over-confident predictions. The standard practices of…

Computer Vision and Pattern Recognition · Computer Science 2024-02-01 Balamurali Murugesan , Bingyuan Liu , Adrian Galdran , Ismail Ben Ayed , Jose Dolz

Labeling medical images is a major bottleneck in the field of medical imaging, as it requires domain-specific expertise, and it gets further complicated due to variability across different medical centers and different imaging devices. Such…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Sapna Sachan , Rakesh Kumar Sanodiya , Amulya Kumar Mahto

Fusing and balancing multi-modal inputs from novel sensors for dense prediction tasks, particularly semantic segmentation, is critically important yet remains a significant challenge. One major limitation is the tendency of multi-modal…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Xu Zheng , Yuanhuiyi Lyu , Lutao Jiang , Danda Pani Paudel , Luc Van Gool , Xuming Hu

Uncertainty quantification in automated image analysis is highly desired in many applications. Typically, machine learning models in classification or segmentation are only developed to provide binary answers; however, quantifying the…

This paper focuses on the uncertainty estimation for white matter lesions (WML) segmentation in magnetic resonance imaging (MRI). On one side, voxel-scale segmentation errors cause the erroneous delineation of the lesions; on the other…

Image and Video Processing · Electrical Eng. & Systems 2023-11-16 Nataliia Molchanova , Vatsal Raina , Andrey Malinin , Francesco La Rosa , Henning Muller , Mark Gales , Cristina Granziera , Mara Graziani , Meritxell Bach Cuadra

Distribution shifts pose significant challenges for model calibration and model selection tasks in the unsupervised domain adaptation problem -- a scenario where the goal is to perform well in a distribution shifted domain without labels.…

Machine Learning · Computer Science 2024-07-18 Taejong Joo , Diego Klabjan

Deep learning (DL) networks have recently been shown to outperform other segmentation methods on various public, medical-image challenge datasets [3,11,16], especially for large pathologies. However, in the context of diseases such as…

Computer Vision and Pattern Recognition · Computer Science 2018-10-18 Tanya Nair , Doina Precup , Douglas L. Arnold , Tal Arbel

Model calibration measures the agreement between the predicted probability estimates and the true correctness likelihood. Proper model calibration is vital for high-risk applications. Unfortunately, modern deep neural networks are poorly…

Image and Video Processing · Electrical Eng. & Systems 2022-09-14 Skylar E. Stolte , Kyle Volle , Aprinda Indahlastari , Alejandro Albizu , Adam J. Woods , Kevin Brink , Matthew Hale , Ruogu Fang

The need for training data can impede the adoption of novel imaging modalities for learning-based medical image analysis. Domain adaptation methods partially mitigate this problem by translating training data from a related source domain to…

Computer Vision and Pattern Recognition · Computer Science 2021-01-19 Eleni Chiou , Francesco Giganti , Shonit Punwani , Iasonas Kokkinos , Eleftheria Panagiotaki

Domain shift, the mismatch between training and testing data characteristics, causes significant degradation in the predictive performance in multi-source imaging scenarios. In medical imaging, the heterogeneity of population, scanners and…

Machine Learning · Computer Science 2021-12-21 Rongguang Wang , Pratik Chaudhari , Christos Davatzikos

Deep learning algorithms utilizing magnetic resonance (MR) images have demonstrated cutting-edge proficiency in autonomously segmenting multiple sclerosis (MS) lesions. Despite their achievements, these algorithms may struggle to extend…

Image and Video Processing · Electrical Eng. & Systems 2023-11-01 Jinwei Zhang , Lianrui Zuo , Blake E. Dewey , Samuel W. Remedios , Savannah P. Hays , Dzung L. Pham , Jerry L. Prince , Aaron Carass

Semantic segmentation is a critical step in automated image interpretation and analysis where pixels are classified into one or more predefined semantically meaningful classes. Deep learning approaches for semantic segmentation rely on…

Computer Vision and Pattern Recognition · Computer Science 2023-07-10 Tushar Kataria , Beatrice Knudsen , Shireen Elhabian

The domain shift in pathological segmentation is an important problem, where a network trained by a source domain (collected at a specific hospital) does not work well in the target domain (from different hospitals) due to the different…

Computer Vision and Pattern Recognition · Computer Science 2023-04-27 Xiaoqing Liu , Kengo Araki , Shota Harada , Akihiko Yoshizawa , Kazuhiro Terada , Mariyo Kurata , Naoki Nakajima , Hiroyuki Abe , Tetsuo Ushiku , Ryoma Bise

The insertion of deep learning in medical image analysis had lead to the development of state-of-the art strategies in several applications such a disease classification, as well as abnormality detection and segmentation. However, even the…

Image and Video Processing · Electrical Eng. & Systems 2022-02-24 Mauricio Orbes-Arteaga , Thomas Varsavsky , Lauge Sorensen , Mads Nielsen , Akshay Pai , Sebastien Ourselin , Marc Modat , M Jorge Cardoso

Automated segmentation of multiple sclerosis (MS) lesions using multicontrast magnetic resonance (MR) images improves efficiency and reproducibility compared to manual delineation, with deep learning (DL) methods achieving state-of-the-art…

Deep learning has shown remarkable progress in medical image semantic segmentation, yet its success heavily depends on large-scale expert annotations and consistent data distributions. In practice, annotations are scarce, and images are…

Computer Vision and Pattern Recognition · Computer Science 2026-01-26 Ba-Thinh Lam , Thanh-Huy Nguyen , Hoang-Thien Nguyen , Quang-Khai Bui-Tran , Nguyen Lan Vi Vu , Phat K. Huynh , Ulas Bagci , Min Xu

This paper presents a simple and effective generalization method for magnetic resonance imaging (MRI) segmentation when data is collected from multiple MRI scanning sites and as a consequence is affected by (site-)domain shifts. We propose…

Image and Video Processing · Electrical Eng. & Systems 2019-10-23 Shahab Aslani , Vittorio Murino , Michael Dayan , Roger Tam , Diego Sona , Ghassan Hamarneh