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Hsp70 molecular chaperones are abundant ATP-dependent nanomachines that actively reshape non-native, misfolded proteins and assist a wide variety of essential cellular processes. Here we combine complementary computational/theoretical…

Biomolecules · Quantitative Biology 2019-04-02 Salvatore Assenza , Alberto S. Sassi , Ruth Kellner , Ben Schuler , Paolo De Los Rios , Alessandro Barducci

Water molecules, confined in a carbon nanotube, were monitored using molecular dynamics simulation. Spontaneous directional transportation during a long timescale was observed in the symmetrical nanochannel by a ratchet-like mechanism. This…

Biological Physics · Physics 2008-03-21 Rongzheng Wan , Hangjun Lu , Jinyuan Li , Jingdong Bao , Jun Hu , Haiping Fang

The integration of the coupling effects of intrinsic wettability and surface charge in a nanochannel can cause non-intuitive behavior in the electrokinetic energy conversion processes. We demonstrate that in a nanofluidic device the energy…

Fluid Dynamics · Physics 2015-11-12 Chirodeep Bakli , Suman Chakraborty

Rotary motors play key roles in energy transduction, from macroscale windmills to nanoscale turbines such as ATP synthase in cells. Despite our capabilities to construct engines at many scales, developing functional synthetic turbines at…

Hybrid plasmonic devices involve a nanostructured metal supporting localized surface plasmons to amplify light-matter interaction, and a non-plasmonic material to functionalize charge excitations. Application-relevant epitaxial…

Biological nanomachines are nanometer-size macromolecular complexes that catalyze chemical reactions in the presence of substrate molecules. The catalytic functions carried out by such nanomachines in the cytoplasm, and biological membranes…

Soft Condensed Matter · Physics 2022-11-22 Yuto Hosaka , Shigeyuki Komura

As a core device of energy Internet, the energy router is deployed to manage energy flow between the renewable energy and electric grid. In this paper, a hierarchical structure of grid energy router is proposed to greatly facilitate…

Systems and Control · Electrical Eng. & Systems 2020-12-22 M. F. Chen , M. C. Xia , Q. F. Chen

Self-organization creates new order and shifts sub-boundaries while reorganizing energy and entropy within a control volume. This article examines pathway selection and tests whether maximizing the entropy generation rate can forecast…

Materials Science · Physics 2026-03-10 J. A. Sekhar

We present a self-contained engine, which is made of one or more two-level systems, each of which is coupled to a single bath, as well as to a common load composed of a particle on a tilted lattice. We show that the energy and the entropy…

Quantum Physics · Physics 2017-03-22 Colin Teo , Ulf Bissbort , Dario Poletti

Molecular dynamics simulations are often used to provide feedback in the design workflow of DNA nanostructures. However, even with coarse-grained models, convergence of distributions from unbiased simulation is slow, limiting applications…

Soft Condensed Matter · Physics 2022-03-16 W. T. Kaufhold , W. Pfeifer , C. E. Castro , L. Di Michele

We develop a dynamical theory of heat transfer between two nano systems. In particular, we consider the resonant heat transfer between two nanoparticles due to the coupling of localized surface modes having a finite spectral width. We model…

Mesoscale and Nanoscale Physics · Physics 2013-02-27 Svend-Age Biehs , Girish S. Agarwal

Soft nanosystems are electronic nanodevices, such as suspended carbon nanotubes or molecular junctions, whose transport properties are modulated by soft internal degrees of freedom, for example slow vibrational modes. In this review,…

Mesoscale and Nanoscale Physics · Physics 2016-03-24 A. Nocera , C. A. Perroni , V. Marigliano Ramaglia , V. Cataudella

Adiabatic techniques offer some of the most promising tools to achieve high-fidelity control of the centre-of-mass degree of freedom of single atoms. As their main requirement is to follow an eigenstate of the system, constraints on timing…

Quantum Physics · Physics 2013-12-23 T. Morgan , L. J. O'Riordan , N. Crowley , B. O'Sullivan , Th. Busch

Proteins are large and complex molecular machines. In order to perform their function, most of them need energy, e.g. either in the form of a photon, like in the case of the visual pigment rhodopsin, or through the breaking of a chemical…

Biomolecules · Quantitative Biology 2009-11-13 Francesco Piazza , Yves-Henri Sanejouand

ATPases cyclically convert chemical energy in the form of ATP gradients into directed motion inside cells. To function, ATPases rely on allosteric communication between at least two binding sites, an internal signaling mechanism that is not…

Molecular Networks · Quantitative Biology 2025-12-22 Tosan Omabegho

Due to the subtle balance of intermolecular interactions that govern structure-property relations, predicting the stability of crystal structures formed from molecular building blocks is a highly non-trivial scientific problem. A…

Chemical Physics · Physics 2022-12-26 Rose K. Cersonsky , Maria Pakhnova , Edgar A. Engel , Michele Ceriotti

Recent theoretical research on the fundamentals of statistical mechanics has led to a remarkable discovery [2-4]: with a locally nonchaotic energy barrier, a macroscopic system may produce useful work in a cycle by absorbing heat from a…

Soft Condensed Matter · Physics 2025-11-10 Yu Qiao , Meng Wang

In equilibrium self-assembly, microscopic building blocks spontaneously self-organize into stable structures as dictated by their interaction potentials, which limits the accessible structural features to those that correspond to global…

Soft Condensed Matter · Physics 2026-04-17 Pepijn G. Moerman , Chenghung Chou , Thomas E. Videbæk , W. Benjamin Rogers , Rebecca Schulman

Despite all the advances achieved in the field of tumor-biology research, in most cases conventional therapies including chemotherapy are still the leading choices. The main disadvantage of these treatments, in addition to the low…

Tissues and Organs · Quantitative Biology 2024-01-25 Paola Sanchez-Moreno , Juan Luis Ortega-Vinuesa , Jose Manuel Peula-Garcia , Juan Antonio Marchal , Houria Boulaiz

A conceptual model for targeted particle delivery is proposed using controlled vortex ring reconnection. Entrained particles can be efficiently transported within the core of the vortex ring which is propelled via self-induction. A pair of…

Fluid Dynamics · Physics 2024-06-19 Joseph Mouallem , Joshua Wawryk , Hamid Daryan , Zhao Pan , Jean-Pierre Hickey
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