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Control contraction metrics (CCMs) provide a framework to co-synthesize a controller and a corresponding contraction metric -- a positive-definite Riemannian metric under which a closed-loop system is guaranteed to be incrementally…

Machine Learning · Computer Science 2025-06-23 Minjae Cho , Hiroyasu Tsukamoto , Huy Trong Tran

Molecular dynamics simulations provide theoretical insight into the microscopic behavior of materials in condensed phase and, as a predictive tool, enable computational design of new compounds. However, because of the large temporal and…

Chemical Physics · Physics 2020-06-18 Wujie Wang , Rafael Gómez-Bombarelli

Continuous-time generative models for crystalline materials enable inverse materials design by learning to predict stable crystal structures, but incorporating explicit target properties into the generative process remains challenging.…

Machine Learning · Computer Science 2026-02-03 Philipp Hoellmer , Stefano Martiniani

Reinforcement Learning (RL) faces significant challenges in adaptive healthcare interventions, such as dementia care, where data is scarce, decisions require interpretability, and underlying patient-state dynamic are complex and causal in…

Robotics · Computer Science 2025-12-02 Wenzheng Zhao , Ran Zhang , Ruth Palan Lopez , Shu-Fen Wung , Fengpei Yuan

This paper proposes, implements, and evaluates a reinforcement learning (RL)-based computational framework for automatic mesh generation. Mesh generation plays a fundamental role in numerical simulations in the area of computer aided design…

Machine Learning · Computer Science 2024-06-07 Jie Pan , Jingwei Huang , Gengdong Cheng , Yong Zeng

Conversational recommender systems (CRS) enable the traditional recommender systems to explicitly acquire user preferences towards items and attributes through interactive conversations. Reinforcement learning (RL) is widely adopted to…

Information Retrieval · Computer Science 2021-05-21 Yang Deng , Yaliang Li , Fei Sun , Bolin Ding , Wai Lam

Reinforcement learning (RL) over text representations can be effective for finding high-value policies that can search over graphs. However, RL requires careful structuring of the search space and algorithm design to be effective in this…

Machine Learning · Computer Science 2023-10-05 Raj Ghugare , Santiago Miret , Adriana Hugessen , Mariano Phielipp , Glen Berseth

The Congestion Control (CC) module plays a critical role in the Transmission Control Protocol (TCP), ensuring the stability and efficiency of network data transmission. The CC approaches that are commonly used these days employ…

Networking and Internet Architecture · Computer Science 2025-09-15 Jinming Xing , Muhammad Shahzad

The development of multicomponent hydrogels has gained a lot of attention in the field of soft matter, as precise tuning of the chemical nature and colloidal properties of each component brings mechanical and functional benefits compared to…

Soft Condensed Matter · Physics 2025-09-15 Thuy-Linh Phi , Eero Kontturi , Niki Baccile

Conventional reinforcement learning (RL) algorithms exhibit broad generality in their theoretical formulation and high performance on several challenging domains when combined with powerful function approximation. However, developing RL…

Machine Learning · Computer Science 2023-11-07 Joseph Modayil , Zaheer Abbas

Recent work has shown the potential of graph neural networks to efficiently predict material properties, enabling high-throughput screening of materials. Training these models, however, often requires large quantities of labelled data,…

Machine Learning · Computer Science 2022-11-28 Teddy Koker , Keegan Quigley , Will Spaeth , Nathan C. Frey , Lin Li

Data-based discovery of effective, coarse-grained (CG) models of high-dimensional dynamical systems presents a unique challenge in computational physics and particularly in the context of multiscale problems. The present paper offers a…

Computational Physics · Physics 2020-08-26 Sebastian Kaltenbach , Phaedon-Stelios Koutsourelakis

Contrastive Reinforcement Learning (CRL) provides a promising framework for extracting useful structured representations from unlabeled interactions. By pulling together state-action pairs and their corresponding future states, while…

Robotics · Computer Science 2025-07-23 Arsh Tangri , Nichols Crawford Taylor , Haojie Huang , Robert Platt

This study introduces the Multi-Scale Weight-Based Pairwise Coarsening and Contrastive Learning (MPCCL) model, a novel approach for attributed graph clustering that effectively bridges critical gaps in existing methods, including long-range…

Machine Learning · Computer Science 2025-07-29 Binxiong Li , Yuefei Wang , Binyu Zhao , Heyang Gao , Benhan Yang , Quanzhou Luo , Xue Li , Xu Xiang , Yujie Liu , Huijie Tang

Coarse-graining is a powerful tool for extending the reach of dynamic models of proteins and other biological macromolecules. Topological coarse-graining, in which biomolecules or sets thereof are represented via graph structures, is a…

Biomolecules · Quantitative Biology 2021-09-15 Vy Duong , Elizabeth Diessner , Gianmarc Grazioli , Rachel W. Martin , Carter T. Butts

We introduce a general framework for constructing coarse-grained potential models without ad hoc approximations such as limiting the potential to two- and/or three-body contributions. The scheme, called Deep Coarse-Grained Potential…

Chemical Physics · Physics 2018-08-15 Linfeng Zhang , Jiequn Han , Han Wang , Roberto Car , Weinan E

Leading graph contrastive learning (GCL) methods perform graph augmentations in two fashions: (1) randomly corrupting the anchor graph, which could cause the loss of semantic information, or (2) using domain knowledge to maintain salient…

Machine Learning · Computer Science 2022-06-17 Sihang Li , Xiang Wang , An zhang , Yingxin Wu , Xiangnan He , Tat-Seng Chua

Sampling equilibrium molecular configurations from the Boltzmann distribution is a longstanding challenge. Boltzmann Generators (BGs) address this by combining exact-likelihood generative models with importance sampling, but practical…

Machine Learning · Computer Science 2026-05-29 Weilong Chen , Bojun Zhao , Jan Eckwert , Julija Zavadlav

Constrained Reinforcement Learning (CRL) addresses sequential decision-making problems where agents are required to achieve goals by maximizing the expected return while meeting domain-specific constraints. In this setting, policy-based…

Machine Learning · Computer Science 2025-06-09 Alessandro Montenegro , Leonardo Cesani , Marco Mussi , Matteo Papini , Alberto Maria Metelli

Coarse-grained (CG) molecular dynamics enables the study of biological processes at temporal and spatial scales that would be intractable at an atomistic resolution. However, accurately learning a CG force field remains a challenge. In this…

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