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Fine-tuning Large Language Models (LLMs) is essential for adapting pre-trained models to downstream tasks. Yet traditional first-order optimizers such as Stochastic Gradient Descent (SGD) and Adam incur prohibitive memory and computational…

Molecule optimization is an important problem in chemical discovery and has been approached using many techniques, including generative modeling, reinforcement learning, genetic algorithms, and much more. Recent work has also applied…

Biomolecules · Quantitative Biology 2022-10-31 Elvin Lo , Pin-Yu Chen

This study investigates the spatial reasoning capabilities of vision-language models (VLMs) through Chain-of-Thought (CoT) prompting and reinforcement learning. We begin by evaluating the impact of different prompting strategies and find…

Computer Vision and Pattern Recognition · Computer Science 2025-07-21 Binbin Ji , Siddharth Agrawal , Qiance Tang , Yvonne Wu

Parameter-efficient fine-tuning (PEFT) that was initially developed for exploiting pre-trained large language models has recently emerged as an effective approach to perform transfer learning on computer vision tasks. However, the…

Computer Vision and Pattern Recognition · Computer Science 2024-01-23 Chenyu Lian , Hong-Yu Zhou , Yizhou Yu , Liansheng Wang

With the continuous growth in the number of parameters of transformer-based pretrained language models (PLMs), particularly the emergence of large language models (LLMs) with billions of parameters, many natural language processing (NLP)…

Computation and Language · Computer Science 2023-12-20 Lingling Xu , Haoran Xie , Si-Zhao Joe Qin , Xiaohui Tao , Fu Lee Wang

As foundation models continue to exponentially scale in size, efficient methods of adaptation become increasingly critical. Parameter-efficient fine-tuning (PEFT), a recent class of techniques that require only modifying a small percentage…

Computation and Language · Computer Science 2023-05-01 George Pu , Anirudh Jain , Jihan Yin , Russell Kaplan

Zeroth-order (ZO) optimization enables memory-efficient training of neural networks by estimating gradients via forward passes only, eliminating the need for backpropagation. However, the stochastic nature of gradient estimation…

Machine Learning · Computer Science 2026-03-24 Chen Zhang , Yuxin Cheng , Chenchen Ding , Shuqi Wang , Jingreng Lei , Runsheng Yu , Yik-Chung WU , Ngai Wong

Open-vocabulary semantic segmentation seeks to label each pixel in an image with arbitrary text descriptions. Vision-language foundation models, especially CLIP, have recently emerged as powerful tools for acquiring open-vocabulary…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Zelin Peng , Zhengqin Xu , Zhilin Zeng , Yaoming Wang , Wei Shen

Finetuning language models (LMs) is crucial for adapting the models to downstream data and tasks. However, full finetuning is usually costly. Existing work, such as parameter-efficient finetuning (PEFT), often focuses on \textit{how to…

Computation and Language · Computer Science 2025-06-03 Jian Gu , Aldeida Aleti , Chunyang Chen , Hongyu Zhang

Parameter-efficient fine-tuning (PEFT) methods have emerged as a practical solution for adapting large foundation models to downstream tasks, reducing computational and memory costs by updating only a small subset of parameters. Among them,…

Machine Learning · Computer Science 2025-12-30 Guoan Wan , Tianyu Chen , Fangzheng Feng , Haoyi Zhou , Runhua Xu

The confluence of Federated Learning (FL) and Large Language Models (LLMs) is ushering in a new era in privacy-preserving natural language processing. However, the intensive memory requirements for fine-tuning LLMs pose significant…

Machine Learning · Computer Science 2024-06-18 Zhenqing Ling , Daoyuan Chen , Liuyi Yao , Yaliang Li , Ying Shen

Vision-Language Models (VLMs) excel at high-level scene understanding but falter on fine-grained perception tasks requiring precise localization. This failure stems from a fundamental mismatch, as generating exact numerical coordinates is a…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Peng Liu , Haozhan Shen , Chunxin Fang , Zhicheng Sun , Jiajia Liao , Tiancheng Zhao

Vision-Language Model (VLM) have gained widespread adoption in Open-Vocabulary (OV) object detection and segmentation tasks. Despite they have shown promise on OV-related tasks, their effectiveness in conventional vision tasks has thus far…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Yongchao Feng , Yajie Liu , Shuai Yang , Wenrui Cai , Jinqing Zhang , Qiqi Zhan , Ziyue Huang , Hongxi Yan , Qiao Wan , Chenguang Liu , Junzhe Wang , Jiahui Lv , Ziqi Liu , Tengyuan Shi , Qingjie Liu , Yunhong Wang

Recent vision-language-action models (VLAs) build upon pretrained vision-language models and leverage diverse robot datasets to demonstrate strong task execution, language following ability, and semantic generalization. Despite these…

Robotics · Computer Science 2025-04-29 Moo Jin Kim , Chelsea Finn , Percy Liang

Large language models (LLMs) have shown remarkable abilities in diverse natural language processing (NLP) tasks. The LLMs generally undergo supervised fine-tuning (SFT) followed by preference alignment to be usable in downstream…

Computation and Language · Computer Science 2024-06-27 Shiva Kumar Pentyala , Zhichao Wang , Bin Bi , Kiran Ramnath , Xiang-Bo Mao , Regunathan Radhakrishnan , Sitaram Asur , Na , Cheng

Fine-tuning language models (LMs) has yielded success on diverse downstream tasks, but as LMs grow in size, backpropagation requires a prohibitively large amount of memory. Zeroth-order (ZO) methods can in principle estimate gradients using…

Machine Learning · Computer Science 2024-01-12 Sadhika Malladi , Tianyu Gao , Eshaan Nichani , Alex Damian , Jason D. Lee , Danqi Chen , Sanjeev Arora

Language Models (LLMs) are often quantized to lower precision to reduce the memory cost and latency in inference. However, quantization often degrades model performance, thus fine-tuning is required for various down-stream tasks.…

Machine Learning · Computer Science 2025-02-19 Jiajun Zhou , Yifan Yang , Kai Zhen , Ziyue Liu , Yequan Zhao , Ershad Banijamali , Athanasios Mouchtaris , Ngai Wong , Zheng Zhang

When personalized federated learning (FL) meets large foundation models, new challenges arise from various limitations in resources. In addition to typical limitations such as data, computation, and communication costs, access to the models…

Artificial Intelligence · Computer Science 2023-10-10 Wang Lu , Hao Yu , Jindong Wang , Damien Teney , Haohan Wang , Yiqiang Chen , Qiang Yang , Xing Xie , Xiangyang Ji

Large Language Models (LLMs) are composed of neurons that exhibit various behaviors and roles, which become increasingly diversified as models scale. Recent studies have revealed that not all neurons are active across different datasets,…

Computation and Language · Computer Science 2024-03-19 Haoyun Xu , Runzhe Zhan , Derek F. Wong , Lidia S. Chao

Large vision-language models (VLMs) fine-tuned on specialized visual instruction-following data have exhibited impressive language reasoning capabilities across various scenarios. However, this fine-tuning paradigm may not be able to…

Artificial Intelligence · Computer Science 2024-10-10 Yuexiang Zhai , Hao Bai , Zipeng Lin , Jiayi Pan , Shengbang Tong , Yifei Zhou , Alane Suhr , Saining Xie , Yann LeCun , Yi Ma , Sergey Levine