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While the autonomous assembly of hard nanoparticles with different shapes has been studied extensively both in experiment and simulations, little is known about systems where particle shape can be dynamically altered. DNA origami…

Soft Condensed Matter · Physics 2025-09-30 Denis Dertli , Thomas Speck

Optical antennas have been extensively employed to manipulate the photophysical properties of single photon emitters. Coupling between an emitter and a given resonant mode of an optical antenna depends mainly on three parameters: spectral…

The diversity and heterogeneity of biomarkers has made the development of general methods for single-step quantification of analytes difficult. For individual biomarkers, electrochemical methods that detect a conformational change in an…

At the heart of the structured architecture and complex dynamics of biological systems are specific and timely interactions operated by biomolecules. In many instances, biomolecular agents are spatially confined to flexible lipid membranes…

Soft Condensed Matter · Physics 2020-01-08 Bortolo Mognetti , Pietro Cicuta , Lorenzo Di Michele

The recent development of modular origami structures has ushered in a new era for active metamaterials with multiple degrees of freedom (multi-DOF). Notably, no systematic inverse design approach for volumetric modular origami structures…

Materials Science · Physics 2022-12-13 Kai Xiao , Xiang Zhou , Jaehyung Ju

DNA nanotechnology allows for the realization of complex nanoarchitectures in which the spatial arrangements of different constituents and most functions can be enabled by DNA. When optically active components are integrated in such…

Biological Physics · Physics 2021-05-10 Pengfei Zhan , Steffen Both , Thomas Weiss , Na Liu

Intercalation of drug molecules into synthetic DNA nanostructures formed through self-assembled origami has been postulated as a valuable future method for targeted drug delivery. This is due to the excellent biocompatibility of synthetic…

Cell shape changes, essential for processes such as motility or division, are controlled by the actomyosin cortex that actively remodels biological membranes. Their mechanisms can be deciphered in___vitro using biomimetic reconstituted…

The DNA origami technique has empowered a new paradigm in plasmonics for manipulating light and matter at the nanoscale. This interdisciplinary field has witnessed vigorous growth, outlining a viable route to construct advanced plasmonic…

Applied Physics · Physics 2021-05-06 Chao Zhou , Ling Xin , Xiaoyang Duan , Maximilian J. Urban , Na Liu

Multivalent interactions between deformable mesoscopic units are ubiquitous in biology, where membrane macromolecules mediate the interactions between neighbouring living cells and between cells and solid substrates. Lately, analogous…

Biological Physics · Physics 2015-04-20 S. F. Shimobayashi , B. M. Mognetti , L. Parolini , D. Orsi , P. Cicuta , L. Di Michele

The optical nanocircuit concept provides a predictive framework analogous to an electric RLC circuit, where induced dipoles in plasmonic nanoparticle (NPs), ohmic losses in NPs, and dielectric gaps serve as inductors (L), capacitors (C),…

Lipid membranes regulate the flow of materials and information between cells and their organelles. Further, lipid composition and morphology can play a key role in regulating a variety of biological processes. For example, viral uptake,…

Biomolecules · Quantitative Biology 2009-05-12 Tristan Ursell , Rob Phillips

Artificial intelligence (AI) models remain an emerging strategy to accelerate materials design and development. We demonstrate that convolutional neural network (CNN) models can characterize DNA origami nanostructures employed in…

Chemical Physics · Physics 2025-03-17 Xingfei Wei , Qiankun Mo , Chi Chen , Mark Bathe , Rigoberto Hernandez

Controlling the flow of excitons between organic molecules holds immense promise for various applications, including energy conversion, spectroscopy, photocatalysis, sensing, and microscopy. DNA nanotechnology has shown promise in achieving…

Nanoparticles of plasmonic metals have significantly to the development of spectroscopic techniques, enabling strong confinement of electromagnetic fields at the nanoscale and corresponding signal amplification. However, to date, plasmonic…

Soft interfaces formed by lipid membranes are fundamental to living cells, synthetic cells, and membrane-based soft materials. However, a quantitative framework linking molecular organization with nonlinear interfacial mechanics remains…

Soft Condensed Matter · Physics 2026-01-27 Kazutoshi Masuda , Miho Yanagisawa

Molecular motor proteins form the basis of cellular dynamics. Recently, notable efforts have led to the creation of their DNA-based mimics, which can carry out complex nanoscale motion. However, such functional analogues have not yet been…

Biological Physics · Physics 2021-05-14 Kerstin Goepfrich , Maximilian J. Urban , Christoph Frey , Ilia Platzman , Joachim P. Spatz , Na Liu

Short DNA linkers are increasingly being exploited for driving specific self-assembly of Brownian objects. DNA-functionalised colloids can assemble into ordered or amorphous materials with tailored morphology. Recently, the same approach…

Soft Condensed Matter · Physics 2015-01-12 Lucia Parolini , Bortolo M. Mognetti , Jurij Kotar , Erika Eiser , Pietro Cicuta , Lorenzo Di Michele

DNA monolayers with inherent chirality play a pivotal role across various domains, including biosensors, DNA chips, and bioelectronics. Nonetheless, conventional DNA chiral monolayers, typically constructed from single-stranded DNA (ssDNA)…

Selective configuration control of plasmonic nanostructures using either top-down or bottom-up approaches has remained challenging in the field of active plasmonics. We demonstrate the realization of DNA-assembled reconfigurable plasmonic…

Optics · Physics 2021-05-04 Anton Kuzyk , Maximilian J. Urban , Andrea Idili , Francesco Ricci , Na Liu